,Table of Content sq sq
Chapter 01: Cellular Biology...................................................................................................................................... 4
sq sq sq
Chapter 02: Genes and Genetic Diseases ................................................................................................................ 13
sq sq sq sq sq
Chapter 03: Epigenetics and Disease ....................................................................................................................... 23
sq sq sq sq
U SN T O .................................................................................................................................................................... 23
sq sq
Chapter 04: Altered Cellular and Tissue Biology ................................................................................................... 27
sq sq sq sq sq sq
Huether & McCance: Understanding Pathophysiology, 6th Edition ....................................................................... 39
sq sq sq sq sq sq
Chapter 06: Innate Immunity: Inflammation and Wound Healing Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................... 48
sq sq
Chapter 07: Adaptive Immunity ............................................................................................................................... 60
sq sq sq
Chapter 08: Infection and Defects in Mechanisms of Defense Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................... 66
sq sq
SINGTB.COM ............................................................................................................................................................... 74
Chapter 09: Stress and Disease ................................................................................................................................ 76
sq sq sq sq
Chapter 10: Biology, Clinical Manifestations, and Treatment of Cancer Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................... 81
sq sq
Chapter 11: Cancer Epidemiology ........................................................................................................................... 87
sq sq sq
Chapter 12: Cancer in Children ............................................................................................................................... 91
sq sq sq sq
Chapter 13: Structure and Function of theNeurologic System Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition ................................................................................................................................... 94
sq sq
Chapter 14: Pain, Temperature, Sleep, and Sensory Function Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................. 105
sq sq
Chapter 15: Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function ......................... 116
sq sq sq sq sq sq sq sq sq sq
Chapter 16: Disorders of theCentral and Peripheral Nervous Systems and theNeuromuscular Junction ........... 126
sq sq sq sq sq sq sq sq sq sq sq
Chapter 17: Alterations of Neurologic Function in Children Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition ................................................................................................................................. 138
sq sq
Chapter 18: Mechanisms of Hormonal Regulation ............................................................................................... 147
sq sq sq sq sq
Chapter 19: Alterations of Hormonal Regulation .................................................................................................. 156
sq sq sq sq sq
Chapter 20: Structure and Function of the Hematologic System Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................. 169
sq sq
Chapter 21: Alterations of Hematologic Function ................................................................................................. 176
sq sq sq sq sq
INGTB.COM ............................................................................................................................................................... 177
Chapter 22: Alterations of Hematologic Function in Children Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition ................................................................................................................................. 192
sq sq
Chapter 23: Structure and Function of the Cardiovascular and Lymphatic Systems Huether & McCance:
sq sq sq sq sq sq sq sq sq sq sq sq sq sq
Understanding Pathophysiology, 6th Edition ......................................................................................................... 200
sq sq sq
Chapter 24: Alterations of Cardiovascular Function ............................................................................................. 210
sq sq sq sq sq
U SN T O .................................................................................................................................................................. 210
sq sq
SINGTB.COM ............................................................................................................................................................. 223
U SN T O .................................................................................................................................................................. 226
sq sq
U SN T O .................................................................................................................................................................. 228
sq sq
Chapter 25: Alterations of Cardiovascular Function in Children Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................. 229
sq sq
SNT
sq sq s q s q O ................................................................................................................................................................... 232
Chapter 26: Structure and Function of the Pulmonary System Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................. 236
sq sq
Chapter 27: Alterations of Pulmonary Function .................................................................................................... 245
sq sq sq sq sq
, Chapter 28: Alterations of Pulmonary Function in Children Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition ................................................................................................................................. 257
sq sq
Chapter 29: Structure and Function of the Renal and Urologic Systems Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition ................................................................................................................................. 265
sq sq
Chapter 30: Alterations of Renal and Urinary Tract Function Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition ................................................................................................................................. 273
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Chapter 31: Alterations of Renal and Urinary Tract Function in Children Huether & McCance:
sq sq sq sq sq sq sq sq sq sq sq sq sq sq
Understanding Pathophysiology, 6th Edition ........................................................................................................ 280
sq sq sq
Chapter 32: Structure and Function of the Reproductive Systems Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................. 286
sq sq
Chapter 33: Alterations of the Female Reproductive System Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition ................................................................................................................................. 295
sq sq
Chapter 34: Alterations of the Male Reproductive System .................................................................................. 300
sq sq sq sq sq sq sq
Chapter 35: Structure and Function of the Digestive System Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition ................................................................................................................................. 305
sq sq
Chapter 36: Alterations of Digestive Function ...................................................................................................... 312
sq sq sq sq sq
Chapter 37: Alterations of Digestive Function in Children .................................................................................. 325
sq sq sq sq sq sq sq
Chapter 38: Structure and Function of the Musculoskeletal System Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................. 334
sq sq
U SN T O .................................................................................................................................................................. 337
sq sq
Chapter 39: Alterations of Musculoskeletal Function ........................................................................................... 342
sq sq sq sq sq
Chapter 40: Alterations of Musculoskeletal Function in Children Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................. 352
sq sq
U SN T O .................................................................................................................................................................. 354
sq sq
Chapter 41: Structure, Function, and Disorders of the Integument Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................. 357
sq sq
Chapter 42: Alterations of the Integument in Children ........................................................................................ 366
sq sq sq sq sq sq sq
, Chapter 01: Cellular Biology
sq sq sq
Huether & McCance: Understanding Pathophysiology, 7th Edition
sq sq sq sq sq sq
MULTIPLE CHOICE sq
1. A student is observing a cell under the microscope. It is observed to have supercoiled
sq sq sq sq sq sq sq sq sq sq sq sq sq sq sq
DNA with histones. Which of the following would also be observed by the student?
sq sq sq sq sq sq sq sq sq sq sq sq sq
a. A single circular chromosome
sq sq sq
b. A nucleus sq
c. Free-floating nuclear material sq sq
d. No organelles sq
ANS: s q B
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within
sq sq sq sq sq sq sq sq sq sq sq sq sq sq sq sq
its nucleus; thus, the nucleus should be observed. A single circular chromosome called a
sq sq sq sq sq sq sq sq sq sq sq sq sq sq
prokaryote contains free-floating nuclear material but has no organelles.
sq sq sq sq sq sq sq sq
REF: p. 2 sq sq
2. A nurse is instructing the staff about cellular functions. Which cellular function is the
sq sq sq sq sq sq sq sq sq sq sq sq sq sq
nurse describing when an isolated cell absorbs oxygen and uses it to transform nutrients
sq sq sq sq sq sq sq sq sq sq sq sq sq sq
to energy?
sq
a. Metabolic absorption sq
b. Communication
c. Secretion
d. Respiration
ANS: D sq
The cell’s ability to absorb oxygen is referred to as respiration while its communication ability
sq sq sq sq sq sq sq sq sq sq sq sq sq sq sq
involves maintenance of a steady dynamic state, metabolic absorption provides nutrition, and
sq sq sq sq sq sq sq sq sq sq sq sq
secretion allows for the synthesizing of new substances.
sq sq sq sq sq sq sq
REF: p. 2 sq sq
3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would
sq sq sq sq sq sq sq sq sq sq sq sq sq sq
most of the genetic information be contained?
sq sq sq sq sq sq
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm sq
ANS: C sq
The region of the cell that contains genetic material, including a large amount of
sq sq sq sq sq sq sq sq sq sq sq sq sq sq
ribonucleic acid, most of the DNA, and DNA-binding proteins, is the nucleolus, which is
sq sq sq sq sq sq sq sq sq sq sq sq sq sq
located within the cell’s nucleus. Mitochondria is associated with cellular respiration,
sq sq sq sq sq sq sq sq sq sq sq
while ribosomes are involved with protein manufacturing. Cytoplasm is a fluid filling
sq sq sq sq sq sq sq sq sq sq sq sq
that is a component of the cell.
sq sq sq sq sq sq
REF: p. 2 sq sq
Chapter 01: Cellular Biology...................................................................................................................................... 4
sq sq sq
Chapter 02: Genes and Genetic Diseases ................................................................................................................ 13
sq sq sq sq sq
Chapter 03: Epigenetics and Disease ....................................................................................................................... 23
sq sq sq sq
U SN T O .................................................................................................................................................................... 23
sq sq
Chapter 04: Altered Cellular and Tissue Biology ................................................................................................... 27
sq sq sq sq sq sq
Huether & McCance: Understanding Pathophysiology, 6th Edition ....................................................................... 39
sq sq sq sq sq sq
Chapter 06: Innate Immunity: Inflammation and Wound Healing Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................... 48
sq sq
Chapter 07: Adaptive Immunity ............................................................................................................................... 60
sq sq sq
Chapter 08: Infection and Defects in Mechanisms of Defense Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................... 66
sq sq
SINGTB.COM ............................................................................................................................................................... 74
Chapter 09: Stress and Disease ................................................................................................................................ 76
sq sq sq sq
Chapter 10: Biology, Clinical Manifestations, and Treatment of Cancer Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................... 81
sq sq
Chapter 11: Cancer Epidemiology ........................................................................................................................... 87
sq sq sq
Chapter 12: Cancer in Children ............................................................................................................................... 91
sq sq sq sq
Chapter 13: Structure and Function of theNeurologic System Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition ................................................................................................................................... 94
sq sq
Chapter 14: Pain, Temperature, Sleep, and Sensory Function Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................. 105
sq sq
Chapter 15: Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function ......................... 116
sq sq sq sq sq sq sq sq sq sq
Chapter 16: Disorders of theCentral and Peripheral Nervous Systems and theNeuromuscular Junction ........... 126
sq sq sq sq sq sq sq sq sq sq sq
Chapter 17: Alterations of Neurologic Function in Children Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition ................................................................................................................................. 138
sq sq
Chapter 18: Mechanisms of Hormonal Regulation ............................................................................................... 147
sq sq sq sq sq
Chapter 19: Alterations of Hormonal Regulation .................................................................................................. 156
sq sq sq sq sq
Chapter 20: Structure and Function of the Hematologic System Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................. 169
sq sq
Chapter 21: Alterations of Hematologic Function ................................................................................................. 176
sq sq sq sq sq
INGTB.COM ............................................................................................................................................................... 177
Chapter 22: Alterations of Hematologic Function in Children Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition ................................................................................................................................. 192
sq sq
Chapter 23: Structure and Function of the Cardiovascular and Lymphatic Systems Huether & McCance:
sq sq sq sq sq sq sq sq sq sq sq sq sq sq
Understanding Pathophysiology, 6th Edition ......................................................................................................... 200
sq sq sq
Chapter 24: Alterations of Cardiovascular Function ............................................................................................. 210
sq sq sq sq sq
U SN T O .................................................................................................................................................................. 210
sq sq
SINGTB.COM ............................................................................................................................................................. 223
U SN T O .................................................................................................................................................................. 226
sq sq
U SN T O .................................................................................................................................................................. 228
sq sq
Chapter 25: Alterations of Cardiovascular Function in Children Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................. 229
sq sq
SNT
sq sq s q s q O ................................................................................................................................................................... 232
Chapter 26: Structure and Function of the Pulmonary System Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................. 236
sq sq
Chapter 27: Alterations of Pulmonary Function .................................................................................................... 245
sq sq sq sq sq
, Chapter 28: Alterations of Pulmonary Function in Children Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition ................................................................................................................................. 257
sq sq
Chapter 29: Structure and Function of the Renal and Urologic Systems Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition ................................................................................................................................. 265
sq sq
Chapter 30: Alterations of Renal and Urinary Tract Function Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition ................................................................................................................................. 273
sq sq
Chapter 31: Alterations of Renal and Urinary Tract Function in Children Huether & McCance:
sq sq sq sq sq sq sq sq sq sq sq sq sq sq
Understanding Pathophysiology, 6th Edition ........................................................................................................ 280
sq sq sq
Chapter 32: Structure and Function of the Reproductive Systems Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................. 286
sq sq
Chapter 33: Alterations of the Female Reproductive System Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition ................................................................................................................................. 295
sq sq
Chapter 34: Alterations of the Male Reproductive System .................................................................................. 300
sq sq sq sq sq sq sq
Chapter 35: Structure and Function of the Digestive System Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition ................................................................................................................................. 305
sq sq
Chapter 36: Alterations of Digestive Function ...................................................................................................... 312
sq sq sq sq sq
Chapter 37: Alterations of Digestive Function in Children .................................................................................. 325
sq sq sq sq sq sq sq
Chapter 38: Structure and Function of the Musculoskeletal System Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................. 334
sq sq
U SN T O .................................................................................................................................................................. 337
sq sq
Chapter 39: Alterations of Musculoskeletal Function ........................................................................................... 342
sq sq sq sq sq
Chapter 40: Alterations of Musculoskeletal Function in Children Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................. 352
sq sq
U SN T O .................................................................................................................................................................. 354
sq sq
Chapter 41: Structure, Function, and Disorders of the Integument Huether & McCance: Understanding
sq sq sq sq sq sq sq sq sq sq sq sq sq
Pathophysiology, 6th Edition .................................................................................................................................. 357
sq sq
Chapter 42: Alterations of the Integument in Children ........................................................................................ 366
sq sq sq sq sq sq sq
, Chapter 01: Cellular Biology
sq sq sq
Huether & McCance: Understanding Pathophysiology, 7th Edition
sq sq sq sq sq sq
MULTIPLE CHOICE sq
1. A student is observing a cell under the microscope. It is observed to have supercoiled
sq sq sq sq sq sq sq sq sq sq sq sq sq sq sq
DNA with histones. Which of the following would also be observed by the student?
sq sq sq sq sq sq sq sq sq sq sq sq sq
a. A single circular chromosome
sq sq sq
b. A nucleus sq
c. Free-floating nuclear material sq sq
d. No organelles sq
ANS: s q B
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within
sq sq sq sq sq sq sq sq sq sq sq sq sq sq sq sq
its nucleus; thus, the nucleus should be observed. A single circular chromosome called a
sq sq sq sq sq sq sq sq sq sq sq sq sq sq
prokaryote contains free-floating nuclear material but has no organelles.
sq sq sq sq sq sq sq sq
REF: p. 2 sq sq
2. A nurse is instructing the staff about cellular functions. Which cellular function is the
sq sq sq sq sq sq sq sq sq sq sq sq sq sq
nurse describing when an isolated cell absorbs oxygen and uses it to transform nutrients
sq sq sq sq sq sq sq sq sq sq sq sq sq sq
to energy?
sq
a. Metabolic absorption sq
b. Communication
c. Secretion
d. Respiration
ANS: D sq
The cell’s ability to absorb oxygen is referred to as respiration while its communication ability
sq sq sq sq sq sq sq sq sq sq sq sq sq sq sq
involves maintenance of a steady dynamic state, metabolic absorption provides nutrition, and
sq sq sq sq sq sq sq sq sq sq sq sq
secretion allows for the synthesizing of new substances.
sq sq sq sq sq sq sq
REF: p. 2 sq sq
3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would
sq sq sq sq sq sq sq sq sq sq sq sq sq sq
most of the genetic information be contained?
sq sq sq sq sq sq
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm sq
ANS: C sq
The region of the cell that contains genetic material, including a large amount of
sq sq sq sq sq sq sq sq sq sq sq sq sq sq
ribonucleic acid, most of the DNA, and DNA-binding proteins, is the nucleolus, which is
sq sq sq sq sq sq sq sq sq sq sq sq sq sq
located within the cell’s nucleus. Mitochondria is associated with cellular respiration,
sq sq sq sq sq sq sq sq sq sq sq
while ribosomes are involved with protein manufacturing. Cytoplasm is a fluid filling
sq sq sq sq sq sq sq sq sq sq sq sq
that is a component of the cell.
sq sq sq sq sq sq
REF: p. 2 sq sq
