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n by Amy Karch Chapter 1-59 | Complete Guide 2025/26
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Focus on Nursing Pharmacology (9th Edition by Karch)
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Chapter 01 - Introduction to Drugs nm nm nm nm nm
A nurse working in radiology administers iodine to a patient who is having a computed tomography (C
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T) scan. The nurse working on the oncology unit administers chemotherapy to patients who hav
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e cancer. At the Public Health Department, a nurse administers a measles-mumps-
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rubella (MMR) vaccine to a 14-month- nm nm nm nm nm
old child as a routine immunization. Which branch of pharmacology best describes the actions o
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f all three nurses?
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Pharmacoeconomics nm
Pharmacotherapeutics n
m Pharmacodynamics P nm
harmacokinetics Ans n m
: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are involved with clinical p
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harmacology or pharmacotherapeutics, which is a branch of pharmacology that deals with the uses o
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f drugs to treat, prevent, and diagnose disease. The radiology nurse is administering a drug to help
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diagnose a disease. The oncology nurse is administering a drug to help treat a disease.
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Pharmacoeconomics includes any costs involved in drug therapy. Pharmacodynamics involves how a nm nm nm nm nm nm nm nm nm nm nm
drug affects the body and pharmacokinetics is how the body acts on the body.
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A physician has ordered intramuscular (IM) injections of morphine, a narcotic, every 4 hours as needed
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for pain in a motor vehicle accident victim. The nurse is aware this drug has a high abuse pote
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ntial.
Under what category would morphine be classified?
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Schedule I S nm nm
chedule II S nm nm
chedule III n m nm
Schedule IV nm n
m Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II drugs because of severe dependence
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Focus on Nursing Pharmacology (9th Edition by Karch)
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liability. Schedule I drugs have high abuse potential and no accepted medical use. Schedule III dr
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ugs have a lesser abuse potential than II and an accepted medical use. Schedule IV drugs have l
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ow abuse potential and limited dependence liability.
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When involved in phase III drug evaluation studies, what responsibilities would the nurse hav
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e? Working with animals who are given experimental drugs
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Choosing appropriate patients to be involved in the drug study Mo
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nitoring and observing patients closely for adverse effects Conducti
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ng research to determine effectiveness of the drug Ans: C
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Feedback:
Phase III studies involve use of a drug in a vast clinical population in which patients are asked to r
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ecord any symptoms they experience while taking the drugs. Nurses may be responsible for helping
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collect and analyze the information to be shared with the Food and Drug Administration (FDA) bu
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t would not conduct research independently because nurses do not prescribe medications. Use of an
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imals in drug testing is done in the preclinical trials. Select patients who are involved in phase II st
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udies to participate in studies where the participants have the disease the drug is intended to treat.
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These patients are monitored closely for drug action and adverse effects. Phase I studies involve hea
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lthy human volunteers who are usually paid for their participation. Nurses may observe for adverse
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effects and toxicity. nm nm
What concept is considered when generic drugs are substituted for brand name drugs? Bioavai
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lability
Critical concentration nm
nm Distribution
Half-
life Ans: A
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Feedback:
Bioavailability is the portion of a dose of a drug that reaches the systemic circulation and is availab
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le to act on body cells. Binders used in a generic drug may not be the same as those used in the b
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rand name drug. Therefore, the way the body breaks down and uses the drug may differ, which m
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ay eliminate a generic drug substitution. Critical concentration is the amount of a drug that is need
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ed to cause a therapeutic effect and should not differ between generic and brand name medications
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. Distribution is the phase of pharmacokinetics, which involves the movement of a drug to the bod
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y’s tissues and is the
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same in generic and brand name drugs. A drug’s half-
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life is the time it takes for the amount of drug to decrease to half the peak level, which should not
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change when substituting a generic medication.
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A nurse is assessing the patient’s home medication use. After listening to the patient list current medica
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tions, the nurse asks what priority question?
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Do you take any generic medications?
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Are any of these medications orphan drugs?
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Are these medications safe to take during pregnancy?
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Do you take any over-the-counter medications?
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Ans: D
Feedback:
It is important for the nurse to specifically question use of over-the-
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counter medications because patients may not consider them important. The patient is unlikely to kn
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ow the meaning of orphan drugs unless they too are health care providers. Safety during pregnancy,
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use of a generic medication, or classification of orphan drugs are things the patient would be unab
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le to answer but could be found in reference books if the nurse wishes to research them.
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After completing a course on pharmacology for nurses, what will the nurse know? Ever
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ything necessary for safe and effective medication administration
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Current pharmacologic therapy; the nurse will not require ongoing education for 5 year
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s. General drug information; the nurse can consult a drug guide for specific drug inform
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ation. The drug actions that are associated with each classification of medication Ans:
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C
Feedback:
After completing a pharmacology course nurses will have general drug information needed for safe
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and effective medication administration but will need to consult a drug guide for specific drug infor
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mation before administering any medication. Pharmacology is constantly changing, with new drugs
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entering the market and new uses for existing drugs identified. Continuing education in pharmacol
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ogy is essential to safe practice. Nurses tend to become familiar with the medications they administ
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er most often, but there will always be a need to research new drugs and also those the nurse is not
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familiar with because no nurse knows all medications.
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