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Exam (elaborations)

ATI NCLEX Pharmacology Assessment 1 (2025) – 300+ Practice Questions & Detailed Rationales

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Prepare for the ATI NCLEX Pharmacology Assessment with this comprehensive guide featuring 300+ actual exam questions and detailed rationales. Covers medication administration, adverse effects, lab values, patient teaching, and priority nursing actions. Ideal for nursing students and NCLEX candidates. Boost your confidence and test-taking skills – download now!

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ATI NCLEX Pharmacology Assessment 1
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ATI NCLEX Pharmacology Assessment 1











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Institution
ATI NCLEX Pharmacology Assessment 1
Course
ATI NCLEX Pharmacology Assessment 1

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Uploaded on
August 28, 2025
Number of pages
47
Written in
2025/2026
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Exam (elaborations)
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Questions & answers

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ATI NCLEX Pharmacology Assessment 1




A nurse is administering methotrexate to a client who has
lymphosarcoma. The nurse should encourage the client to
maintain an adequate fluid intake to prevent which of the
following adverse effects of the medication


A. Kidney damage
B. Alopecia
C. Thrombocytopenia
D. Dermatitis - . . ANSWER ✓✓ A
The pt needs 2,000-3,000 mL of fluids per day to promote
medication excretion and prevent kidney damage


A nurse is assessing a client for pain who is 4 hr postoperative
following surgery and still experiencing the effects of anesthesia.
Which of the following findings should the nurse identify as an
indication that the client might be experiencing pain and requires
pain medication


A. Reduced blood glucose
B. Pupil constriction

,2|Page


C. Diaphoresis
D. Facial flushing - . . ANSWER ✓✓ C
A client in pain can be come diaphroetic in an attempt to keep the
body temperature under control during stress


--
A, blood glucose can increase in a client who has pain as the
body attempts to make more energy available


B, pupils can dilate in a client who has pain to help improve
vision


D, a client in pain can become pale as the body shifts blood to the
central circulation and away from the peripheral circulation


A nurse is assessing a client who has Alzheimer's disease and is
taking oral rivastigmine. Which of the following findings indicates
the client is experiencing an adverse effect of the medication


A. Diarrhea
B. Tachycardia
C. Dry skin
D. Weight gain - . . ANSWER ✓✓ A

,3|Page


Diarrhea is an adverse effect of this med d/t the peripheral
cholinergic effect of the med


--
B, the med is a cholinesterase inhibitor, which causes
cholinergic actions such as bradycardia, AV block, and cardiac
arrest


C,the med is a cholinesterase inhibitor, which causes cholinergic
actions such a diaphroesis


D, the med is a cholinesterase inhibitor, which causes
cholinergic actions such as anorexia, nausea, vomiting, diarrhea,
and abdominal pain which can lead to weight loss


A nurse is assessing a client who has been taking simvastatin
and has alanine aminotransferase (ALT) and aspartate
aminotransferase (AST) elevations. Which of the following
findings is the nurse's priority assessment


A. Knowledge of the medication's adverse effects
B. Dietary intake of grapefruit
C. Changes in exercise routine
D. Recent weight gain - . . ANSWER ✓✓ B

, 4|Page


The greatest risk to this client is injury from liver damage due to
elevated simvastatin levels, finding out that the pt drinks
grapefruit juice is priority. Grapefruit juice inhibits the drug
metabolizing enzyme and hepatic enzyme. The result is
increased blood levels of stimvastatin and the potential for
serious adverse effects, such as elevated liver enzymes and
rhabdomyolysis (Potentially fatal disintegration of muscle tissue)


A nurse is assessing a client who has chronic pain disorder and
is requesting pain medication. Which of the following findings
should the nurse identify as the most reliable indicator of the
client's pain


A. The client's behavior
B. Changes in the client's vital signs
C. The client's facial expression
D. The client's verbal report - . . ANSWER ✓✓ D


The nurse should ask the client about the location, quality, and
intensity of the pain


A nurse is assessing a client who has preeclampsia and is
receiving magnesium sulfate IV therapy. A nurse should identify
which of the following findings as an indication that the client is
having a therapeutic response

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