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Systemic Lupus Erythematosus (SLE) Exam 2025 – Complete Questions with Verified Correct Answers and Detailed Rationales

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This document provides the latest Systemic Lupus Erythematosus (SLE) Exam 2025 with actual exam questions, verified correct answers, and detailed rationales. It covers essential nursing interventions, clinical signs, laboratory findings, patient education, and pharmacologic management of SLE. Topics include early symptoms such as butterfly rash, complications like lupus nephritis and pericarditis, priority nursing care for immune deficiencies, psychosocial considerations, and high-yield laboratory markers such as Anti-Smith antibodies. This is a complete professor-verified and graded A+ resource designed for exam preparation.

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Systemic lupus,
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Uploaded on
August 25, 2025
Number of pages
85
Written in
2025/2026
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SYSTEMIC LUPUS ERYTHEMATOSUS EXAM /SLE EXAM LATEST
2025 ACTUAL EXAM WITH COMPLETE QUESTIONS AND CORRECT
DETAILED ANSWERS (100% VERIFIED ANSWERS) |ALREADY
GRADED A+| ||PROFESSOR VERIFIED|| ||BRANDNEW!!!||

What nursing intervention is most appropriate for a client reporting chest
pain and fatigue related to SLE?

A. Administer epinephrine.

B. Monitor for arrhythmias and fever.

C. Restrict all physical activity.

D. Place the client in a Trendelenburg position. - ANSWER-B. Monitor for
arrhythmias and fever.

Rationale:

Chest pain and fatigue can indicate pericarditis or myocarditis;
monitoring for associated symptoms is crucial.



A client is suspected of having systemic lupus erythematous. The nurse
monitors the client, knowing that which of the following is one of the initial
characteristic sign of systemic lupus erythematous?

1. Weight gain

2. Subnormal temperature

3. Elevated red blood cell count

,2|Page


4. Rash on the face across the bridge of the nose and on the cheeks -
ANSWER-Answer: 4

Rationale: Skin lesions or rash on the face across the bridge of the
nose and on the cheeks is an initial characteristic sign of systemic
lupus erythematosus (SLE). Fever and weight loss may also occur.
Anemia is most likely to occur later in SLE.



The nurse is assisting in planning care for a client with a diagnosis of
immune deficiency. The nurse would incorporate which of the following as
a priority in the plan of care?

1. Protecting the client from infection

2. Providing emotional support to decrease fear

3. Encouraging discussion about lifestyle changes

4. Identifying factors that decreased the immune function - ANSWER-
Answer: 1

Rationale: The client with immune deficiency has inadequate or
absent immune bodies and is at risk for infection. The priority nursing
intervention would be to protect the client from infection. Options 2, 3,
and 4 may be components of care but are not the priority.



The nurse is assigned to care for a client with systemic lupus
erythematosus (SLE). The nurse plans care knowing that this disorder is:

1. A local rash that occurs as a result of allergy

,3|Page


2. A disease caused by overexposure to sunlight

3. An inflammatory disease of collagen contained in connective tissue

4. A disease caused by the continuous release of histamine in the body -
ANSWER-Answer: 3

Rationale: SLE is an inflammatory disease of collagen contained in
connective tissue. Options 1, 2, and 4 are not associated with this
disease.



The nurse is assigned to care for a client admitted to the hospital with a
diagnosis of systemic lupus erythematosus (SLE). The nurse reviews the
health care provider's prescriptions. Which of the following medications
would the nurse expect to be prescribed?

1. Antibiotic

2. Antidiarrheal

3. Corticosteroid

4. Opioid analgesic - ANSWER-Answer: 3

Rationale: Treatment of SLE is based on the systems involved and
symptoms. Treatment normally consists of anti-inflammatory drugs,
corticosteroids, and immunosuppressants. The incorrect options are
not standard components of medication therapy for this disorder.



A nurse is collecting data on a client who complains of fatigue, weakness,
malaise, muscle pain, joint pain at multiple sites, anorexia, and

, 4|Page


photosensitivity. Systematic lupus erythematosus (SLE) is suspected. The
nurse further checks for which of the following that is also indicative of the
presence of SLE?

1. Emboli

2. Ascites

3. Two hemoglobin S genes

4. Butterfly rash on cheeks and bridge of nose - ANSWER-Answer: 4

Rationale: SLE is a chronic inflammatory disease that affects multiple
body systems. A butterfly rash on the cheeks and on the bridge of the
nose is a classic sign of SLE. Option 3 is found in sickle cell anemia.
Options 1 and 2 may be found in many conditions but are not
associated with SLE.



Which client is at the highest risk for systemic lupus erythematous (SLE)?

1. An Asian male

2. A white female

3. An African-American male

4. An African-American female - ANSWER-

Answer: 4

Rationale: SLE affects females more commonly than males. It is more
common in African-American females than in white females.

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