ATI Pharmacology Made Easy 4.0 ~ The Neurological System (Part 1) Exam Questions And Answers 2025/2025

ATI Pharmacology Made Easy 4.0 ~ The Neurological System (Part 1) Exam Questions And Answers 2025/2025 A nurse is teaching a client who has Alzheimer's disease and their caregiver about memantine. Which of the following instructions should the nurse include? A. Increase fluid intake to improve renal excretion. B. Report memory loss or confusion. C. Watch for signs of liver impairment, such as jaundice and abdominal pain. D. Avoid taking over-the-counter antacids. - Correct Answer D. Avoid taking over-the-counter antacids. Rationale: A. It is not necessary to increase fluids. Memantine is essentially unchanged when it is excreted in the urine. Therefore, it is not necessary to increase fluids because fluid intake does not affect this process. B. Clients who have Alzheimer's disease already have and will continue to have memory loss and confusion. The drug can help slow the progressive decline, but will not eliminate the disease's manifestations. C. Memantine should not result in liver impairment, although it should be used cautiously with clients who have severe liver impairment. D. Antacids that contain sodium bicarbonate increase urine alkalinity and can decrease drug excretion, ultimately leading to toxicity.