HESI Pharmacology Exam Practice 2025 (NCLEX PN) 2 VERSIONS ACTUAL EXAM COMPLETE 300 QUESTIONS// DETAILED VERIFIED ANSWERS AND RATIONALES

HESI Pharmacology Exam Practice 20
AW AW AW AW




25 (NCLEX PN) 2 VERSIONS ACTUAL
AW AW AW AW AW AW




EXAM COMPLETE 300 QUESTIONS//
AW AW AW AW




DETAILED VERIFIED ANSWERS AND
AW AW AW AW




RATIONALES
1)AWAAWnurseAWisAWcaringAWforAWaAWclientAWwithAWhyperparathyroidismAWandAWnotesAWthatAWt
heAWclient'sAWserumAWcalciumAWlevelAWisAW13AWmg/dL.AWWhichAWmedicationAWshouldAWtheA
WnurseAWprepareAWtoAWadministerAWasAWprescribedAWtoAWtheAWclient?

1. CalciumAWchloride
2. CalciumAWgluconate
3. CalcitoninAW(Miacalcin)
4. LargeAWdosesAWofAWvitaminAWDAW-
AW3.AWCalcitoninAW(Miacalcin)AWRationale:

TheAWnormalAWserumAWcalciumAWlevelAWisAW8.6AWtoAW10.0AWmg/dL.AWThisAWclientAWisAWexperien
cingAWhypercalcemia.AWCalciumAWgluconateAWandAWcalciumAWchlorideAWareAWmedicationsAWu
sedAWforAWtheAWtreatmentAWofAWtetany,AWwhichAWoccursAWasAWaAWresultAWofAWacuteAWhypocalce
mia.AWInAWhypercalcemia,AWlargeAWdosesAWofAWvitaminAWDAWneedAWtoAWbeAWavoided.AWCalcitoni
n,AWaAWthyroidAWhormone,AWdecreasesAWtheAWplasmaAWcalciumAWlevelAWbyAWinhibitingAWboneAWr
esorptionAWandAWloweringAWtheAWserumAWcalciumAWconcentration.

2.) OralAWironAWsupplementsAWareAWprescribedAWforAWaAW6-year-
oldAWchildAWwithAWironAWdeficiencyAWanemia.AWTheAWnurseAWinstructsAWtheAWmotherAWtoAW
administerAWtheAWironAWwithAWwhichAWbestAWfoodAWitem?
1. Milk
2. Water
3. AppleAWjuice
4. OrangeAWjuiceAW-
AW4.AWOrangeAWjuiceAWRationale:

VitaminAWCAWincreasesAWtheAWabsorptionAWofAWironAWbyAWtheAWbody.AWTheAWmotherAWshouldAWb
eAWinstructedAWtoAWadministerAWtheAWmedicationAWwithAWaAWcitrusAWfruitAWorAWaAWjuiceAWthatAWisA
WhighAWinAWvitaminAWC.AWMilkAWmayAWaffectAWabsorption AWofAWtheAWiron.AWWaterAWwillAWnotAWassi

stAWinAWabsorption.AWOrangeAWjuiceAWcontainsAWaAWgreaterAWamountAWofAWvitaminAWCAWthanAWa
ppleAWjuice.

3.) SalicylicAWacidAWisAWprescribedAWforAWaAWclientAWwithAWaAWdiagnosisAWofAWpsoriasis.AWThe
AWnurseAWmonitorsAWtheAWclient,AWknowingAWthatAWwhichAWofAWthe AWfollowingAWwouldAWindicat

eAWtheAWpresenceAWofAWsystemicAWtoxicityAWfromAWthisAWmedication?
1. Tinnitus
2. Diarrhea

, 3. Constipation
4. DecreasedAWrespirationsAW-
AW1.AWTinnitusAWRationale:

SalicylicAWacidAWisAWabsorbedAWreadilyAWthroughAWtheAWskin,AWandAWsystemicAWtoxicityAW(salicy
lism)AWcanAWresult.AWSymptomsAWincludeAWtinnitus,AWdizziness,AWhyperpnea,AWandAWpsycholo
gicalAWdisturbances.AWConstipationAWandAWdiarrheaAWareAWnotAWassociatedAWwithAWsalicylism
.

4.) TheAWcampAWnurseAWasksAWtheAWchildrenAWpreparingAWtoAWswimAWinAWtheAWlakeAWifAWtheyAW
haveAWappliedAWsunscreen.AWTheAWnurseAWremindsAWtheAWchildrenAWthatAWchemicalAWsunscr
eensAWareAWmostAWeffectiveAWwhenAWapplied:
1. ImmediatelyAWbeforeAWswimming
2. 15AWminutesAWbeforeAWexposureAWtoAWtheAWsun
3. ImmediatelyAWbeforeAWexposureAWtoAWtheAWsun
4. AtAWleastAW30AWminutesAWbeforeAWexposureAWtoAWtheAWsunAW-
AW4.AWAtAWleastAW30AWminutesAWbeforeAWexposureAWtoAWtheAWsun

Rationale:
SunscreensAWareAWmostAWeffectiveAWwhenAWappliedAWatAWleastAW30AWminutesAWbeforeAWexpos
ureAWtoAWtheAWsunAWsoAWthatAWtheyAWcanAWpenetrateAWtheAWskin.AWAllAWsunscreensAWshouldAWbe
AWreappliedAWafterAWswimming AWorAWsweating.




5.) MafenideAWacetateAW(Sulfamylon)AWisAWprescribedAWforAWtheAWclientAWwithAWaAWburnAWinju
ry.AWWhenAWapplyingAWtheAWmedication,AWtheAWclientAWcomplainsAWofAWlocalAWdiscomfortAWan
dAWburning.AWWhichAWofAWtheAWfollowingAWisAWtheAWmostAWappropriateAWnursingAWaction?
1. NotifyingAWtheAWregisteredAWnurse
2. DiscontinuingAWtheAWmedication
3. InformingAWtheAWclientAWthatAWthisAWisAWnormal
4. ApplyingAWaAWthinnerAWfilmAWthanAWprescribedAWtoAWtheAWburnAWsiteAW-
AW3.AWInformingAWtheAWclientAWthatAWthisAWisAWnormal

Rationale:
MafenideAWacetateAWisAWbacteriostaticAWforAWgram-negativeAWandAWgram-
positiveAWorganismsAWandA W isAWusedAWtoAWtreatAWburnsAWtoAWreduceAWbacteriaAWpresentAWinAW
avascularAWtissues.AWTheAWclientAWshouldAWbeAWinformedAWthatAWtheAWmedicationAWwillAWcaus
eAWlocalAWdiscomfortAWandAWburningAWandAWthatAWthisAWisAWaAWnormalAWreaction;AWthereforeAWo
ptionsAW1,AW2,AWandAW4AWareAWincorrect

6.) TheAWburnAWclientAWisAWreceivingAWtreatmentsAWofAWtopicalAWmafenideAWacetateAW(Sulfa
mylon)AWtoAWtheAWsiteAWofAWinjury.AWTheAWnurseAWmonitorsAWtheAWclient,AWknowingAWthatAWw
hichAWofAWtheAWfollowingAWindicatesAWthatAWaAWsystemicAWeffectAWhasAWoccurred?
1. Hyperventilation
2. ElevatedAWbloodAWpressure
3. LocalAWpainAWatAWtheAWburnAWsite
4. LocalAWrashAWatAWtheAWburnAWsiteAW-
AW1.Hyperventilation AWRationale:

MafenideAWacetateAWisAWaAWcarbonicAWanhydraseAWinhibitorAWandAWcanAWsuppressAWrenalAWex
cretionAWofAWacid,AWtherebyAWcausingAWacidosis.AWClientsAWreceivingAWthisAWtreatmentAWshoul
dAWbeAWmonitoredAWforAWsignsAWofAWanAWacid-
baseAWimbalanceAW(hyperventilation).AWIfAWthisAWoccurs,AWtheAWmedicationAWshouldAWbeAWdisc
ontinuedAWforAW1AWtoAW2AWdays.AWOptionsAW3AWandAW4AWdescribeAWlocalAWratherAWthanAWsystemi
c

,effects.AWAnAWelevatedAWbloodAWpressureAWmayAWbeAWexpectedAWfromAWtheAWpainAWthatAWoccu
rsAWwithAWaAWburnAWinjury.

7.) IsotretinoinAWisAWprescribedAWforAWaAWclientAWwithAWsevereAWacne.AWBeforeAWtheAWadmini
strationAWofAWthisAWmedication,AWtheAWnurseAWanticipatesAWthatAWwhichAWlaboratoryAWtestAW
willAWbeAWprescribed?
1. PlateletAWcount
2. TriglycerideAWlevel
3. CompleteAWbloodAWcount
4. WhiteAWbloodAWcellAWcountAW-
AW2.AWTriglyceride AWlevelAWRationale:

IsotretinoinAWcanAWelevateAWtriglycerideAWlevels.AWBloodAWtriglycerideAWlevelsAWshouldAWbeAWm
easuredAWbeforeAWtreatmentAWandAWperiodicallyAWthereafterAWuntilAWtheAWeffectAWonAWtheAWtrigl
yceridesAWhasAWbeenAWevaluated.AWOptionsAW1,AW3,AWandAW4AWdoAWnotAWneedAWtoAWbeAWmonitor
edAWspecificallyAWduringAWthisAWtreatment.

8.) AAWclientAWwithAWsevereAWacneAWisAWseenAWinAWtheAWclinicAWandAWtheAWhealthAWcareAWpr
oviderAW(HCP)AWprescribesAWisotretinoin.AWTheAWnurseAWreviewsAWtheAWclient'sAWmedicat
ionAWrecordAWandAWwouldAWcontactAWtheAW(HCP)AWifAWtheAWclientAWisAWtakingAWwhichAWmed
ication?
1. VitaminAWA
2. DigoxinAW(Lanoxin)
3. FurosemideAW(Lasix)
4. PhenytoinAW(Dilantin)AW-
AW1.AWVitaminAWAAWRationale:

IsotretinoinAWisAWaAWmetaboliteAWofAWvitaminAWAAWandAWcanAWproduceAWgeneralizedAWintensific
ationAWofAWisotretinoinAWtoxicity.AWBecauseAWofAWtheAWpotentialAWforAWincreasedAWtoxicity,AWvita
minAWAAWsupplementsAWshouldAWbeAWdiscontinuedAWbeforeAWisotretinoinAWtherapy.AWOptionsA
W2,AW3,AWandAW4AWareAWnotAWcontraindicatedAWwithAWtheAWuseAWofAWisotretinoin.




9.) TheAWnurseAWisAWapplyingAWaAWtopicalAWcorticosteroidAWtoAWaAWclientAWwithAWeczema.AWThe
AWnurseAWwouldAWmonitorAWforAWtheAWpotentialAWforAWincreasedAWsystemicAWabsorptionAWofAWth

eAWmedicationAWifAWtheAWmedicationAWwereAWbeingAWappliedAWtoAWwhichAWofAWtheAWfollowingAWb
odyAWareas?
1. Back
2. Axilla
3. SolesAWofAWtheAWfeet
4. PalmsAWofAWtheAWhandsAW-
AW2.AWAxillaAWRationale:

TopicalAWcorticosteroidsAWcanAWbeAWabsorbedAWintoAWtheAWsystemicAWcirculation.AWAbsorptio
nAWisAWhigherAWfromAWregionsAWwhereAWtheAWskinAWisAWespeciallyAWpermeableAW(scalp,AWaxilla,A
Wface,AWeyelids,AWneck,AWperineum,AWgenitalia),AWandAWlowerAWfromAWregionsAWinAWwhichAWper

meabilityAWisAWpoorAW(back,AWpalms,AWsoles).

10.) TheAWclinicAWnurseAWisAWperformingAWanAWadmissionAWassessmentAWonAWaAWclient.AW
TheAWnurseAWnotesAWthatAWtheAWclientAWisAWtakingAWazelaicAWacidAW(Azelex).AWBecauseAW
ofAWtheAWmedicationAWprescription,AWtheAWnurseAWwouldAWsuspectAWthatAWtheAWclientAWisAW
beingAWtreatedAWfor:
1. Acne
2. Eczema

, 3. HairAWloss
4. HerpesAWsimplexAW-
AW1.AWAcneAWRationale:

AzelaicAWacidAWisAWaAWtopicalAWmedicationAWusedAWtoAWtreatAWmildAWtoAWmoderateAWacne.AWThe
AWacidAWappearsAWtoAWworkAWbyAWsuppressingAWtheAWgrowthAWofAWPropionibacterium AWacnesAW

andAWdecreasingAWtheAWproliferationAWofAWkeratinocytes.AWOptionsAW2,AW3,AWandAW4AWareAWinco
rrect.

11.) TheAWhealthAWcareAWproviderAWhasAWprescribedAWsilverAWsulfadiazineAW(Silvadene)AWforAW
theAWclientAWwithAWaAWpartial-thicknessAWburn,AWwhichAWhasAWculturedAWpositiveAWforAWgram-
negativeAWbacteria.
TheAWnurseAWisAWreinforcingAWinformationAWtoAWtheAWclientAWaboutAWtheAWmedication.AWWhichAW
statementAWmadeAWbyAWtheAWclientAWindicatesAWaAWlackAWofAWunderstandingAWaboutAWtheAWtrea
tments?
1. "TheAWmedicationAWisAWanAWantibacterial."
2. "TheAWmedicationAWwillAWhelpAWhealAWtheAWburn."
3. "TheAWmedicationAWwillAWpermanentlyAWstainAWmyAWskin."
4. "TheAWmedicationAWshouldAWbeAWappliedAWdirectlyAWtoAWtheAWwound."AW-
AW3.AW"TheAWmedicationAWwillAWpermanentlyAWstainAWmyAWskin."

Rationale:
SilverAWsulfadiazineAW(Silvadene)AWisAWanAWantibacterialAWthatAWhasAWaAWbroadAWspectrumAWo
fAWactivityAWagainstAWgram-negativeAWbacteria,AWgram-
positiveAWbacteria,AWandAWyeast.AWItAWisAWappliedAWdirectlyAWtoAWtheAWwoundAWtoAWassistAWinAWh
ealing.AWItAWdoesAWnotAWstainAWtheAWskin.

12.) AAWnurseAWisAWcaringAWforAWaAWclientAWwhoAWisAWreceivingAWanAWintravenousAW(IV)AWinfusio
nAWofAWanAWantineoplasticAWmedication.AWDuringAWtheAWinfusion,AWtheAWclientAWcomplainsAWofA
WpainAWatAWtheAWinsertionAWsite.AWDuringAWanAWinspection AWofAWtheAWsite,AWthe AWnurseAWnotesAWr

ednessAWandAWswellingAWandAWthatAWtheAWrateAWofAWinfusionAWofAWtheAWmedicationAWhasAWslow
ed.AWTheAWnurseAWshouldAWtakeAWwhichAWappropriateAWaction?
1. NotifyAWtheAWregisteredAWnurse.
2. AdministerAWpainAWmedicationAWtoAWreduceAWtheAWdiscomfort.
3. ApplyAWiceAWandAWmaintainAWtheAWinfusionAWrate,AWasAWprescribed.
4. ElevateAWtheAWextremityAWofAWtheAWIVAWsite,AWandAWslowAWtheAWinfusion.AW-
AW1.AWNotifyAWtheAWregisteredAWnurse.

Rationale:
WhenAWantineoplasticAWmedicationsAW(ChemotheraputicAWAgents)AWareAWadministeredAWvia
AWIV,AWgreatAWcareAWmustAWbeAWtakenAWtoAWpreventAWtheAWmedicationAWfromAWescaping AWintoA

WtheAWtissuesAWsurrounding AWtheAWinjectionAWsite,AWbecause AWpain,AWtissueAWdamage,AWandAW

necrosisAWcanAWresult.AWTheAWnurseAWmonitorsAWforAWsignsAWofAWextravasation,AWsuchAWasAWr
ednessAWorAWswellingAWatAWtheAWinsertionAWsiteAWandAWaAWdecreasedAWinfusionAWrate.AWIfAWextr
avasationAWoccurs,AWtheAWregisteredAWnurseAWneedsAWtoAWbeAWnotified;AWheAWorAWsheAWwillAWt
henAWcontactAWtheAWhealthAWcareAWprovider.

13.) TheAWclientAWwithAWsquamousAWcellAWcarcinomaAWofAWtheAWlarynxAWisAWreceivingAWbleom
ycinAWintravenously.AWTheAWnurseAWcaringAWforAWtheAWclientAWanticipatesAWthatAWwhichAWdiagn
osticAWstudyAWwillAWbeAWprescribed?
1. Echocardiography
2. Electrocardiography
3. CervicalAWradiography
4. PulmonaryAWfunctionAWstudiesAW-AW4.AWPulmonaryAWfunctionAWstudies