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Introduction to Genetic Analysis
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Anthony J.F. Griffiths, John Doebley, Catherine Peichel, and David A. Wassarman
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12th Edition
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,Table of Contents
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Chapter 01 The Genetics Revolution
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Chapter 02 Single Gene Inheritance
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Chapter 03 Independent Assortment of Genes
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Chapter 04 Mapping Eukaryote Chromosomes by Recombination
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Chapter 05 Gene Interaction
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Chapter 06 The Genetics of Bacteria and Their Viruses
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Chapter 07 DNA Structure and Replication
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Chapter 08 RNA Transcription Processing and Decay
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Chapter 09 Proteins and Their Synthesis
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Chapter 10 Gene Isolation and Manipulation
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Chapter 11 Regulation of Gene Expression in Bacteria and Their Viruses
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Chapter 12 Regulation of Gene Expression in Eukaryotes
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Chapter 13 The Genetic Control of Development
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Chapter 14 Genomes and Genomics
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Chapter 15 DNA Damage Repair and Recombination
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Chapter 16 The Dynamic Genome Transposable Elements
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Chapter 17 Large Scale Chromosomal Changes
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Chapter 18 Population Genetics
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Chapter 19 The Inheritance of Complex Traits
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Chapter 20 Evolution of Genes and Traits
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, Test Bank - Introduction to Genetic Analysis, 12th Edition (Griffiths, 2021)
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Chapter 01: The Genetics Revolution
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1. The early 1900s was an important period for genetics due to which of the following major events?
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a. the rediscovery of Gregor Mendel's scientific findings
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b. Watson and Crick solving the structure of DNA x x x x x x x
c. Walter Sutton and Theodore Boveri hypothesizing that chromosomes are the hereditary elements
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d. the rediscovery of Gregor Mendel's scientific findings and Walter Sutton and Theodore Boveri
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hypothesizing that chromosomes are the hereditary elements
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e. All of the answer options are correct.
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ANSWER: e x
2. A sample of normal double-stranded DNA was found to have a guanine content of 18%. What is the expected
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proportion of adenine?
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a. 9%
b. 32%
c. 36%
d. 68%
e. 82%
ANSWER: b x
3. In one strand of DNA, the nucleotide sequence is 5'-ATGC-3'. The complementary sequence in the other
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strand must be
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a. 3'-ATGC-5'.
b. 3'-TACG-5'.
c. 5'-ATCG-3'.
d. 5'-CGTA-3'.
e. 5'-TACG-3'.
ANSWER: b x
4. How many different DNA molecules that are eight-nucleotide-pairs long are theoretically possible?
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a. 24
b. 32
c. 64
d. 256
e. 65,536
ANSWER: e x
5. Which of the following is/are TRUE about genes?
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a. Genes are located on chromosomes. x x x x
b. Genes come in variants known as alleles.
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c. Genes usually encode protein products.
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d. All of the answer options are correct.
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e. None of the answer options is correct.
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ANSWER: d x
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, Test Bank - Introduction to Genetic Analysis, 12th Edition (Griffiths, 2021)
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6. Wild cats (Felis silvestris) and common mice (Mus musculus) are diploid. In wild cats, 2n = 38, while in
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common mice, 2n = 40. Based on this information, we can conclude that wild-cat cells have
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a. less DNA than common-mouse cells.
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b. smaller genomes than common-mouse cells. x x x x
c. fewer DNA molecules than common-mouse cells.
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d. fewer genes than common-mouse cells. x x x x
e. fewer sets of chromosomes than common-mouse cells.
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ANSWER: c x
7. Which of the following is a component of DNA?
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a. alanine
b. arginine
c. cysteine
d. guanine
e. tyrosine
ANSWER: d x
8. Which of the following is/are TRUE of the DNA structure solved by Watson and Crick?
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a. It is a double-helical structure.
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b. Sugar–phosphate backbone is always toward the outside of the DNA. x x x x x x x x x
c. There are two hydrogen bonds between A and T and three hydrogen bonds between C and G.
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d. There are four types of nitrogenous bases.
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e. All of the answer options are correct.
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ANSWER: e x
9. Which of the following is a CORRECT representation of the central dogma?
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a. RNA → DNA → protein x x x x
b. protein → DNA → RNA x x x x
c. DNA → RNA → protein x x x x
d. DNA → protein → DNA x x x x
e. None of the answer options is correct.
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ANSWER: c x
10. You have come across a dog (named Cindy) that does not have a tail. Interestingly, all the puppies produced
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by this dog don't have a tail. If the lack of tail is caused by a genetic mutation, where has this mutation most
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likely taken place?
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a. in Cindy's gametes
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b. in the cells that should normally have given rise to Cindy's tail
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c. in the cells that should normally have given rise to Cindy's and her puppies' tails
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d. in all of Cindy's cells (including her gametes)
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e. in a gamete of one of Cindy's parents
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ANSWER: a x
11. Which of the following features makes a species suitable as a model organism?
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