NBME CBSE QUESTIONS AND CORRECT DETAILED ANSWERS WITH RATIONALES (VERIFIED ANSWERS

NBME CBSE QUESTIONS AND

CORRECT DETAILED ANSWERS

WITH RATIONALES (VERIFIED

ANSWERS)
Quiz Type II pneumocytes

ANS: surfactant (*lecithin*)

Proliferate after injury

Type I progenitors

*Neonatal Respiratory Distress Syndrome*



Quiz Polio live v killed vaccine



ANS: Killed = Salk = IgG



Live = Sabin = IgG + IgA

- can be shed in feces



Quiz Neonatal Respiratory Distress:

Etiology + Tx

,ANS: Maternal DM (*high insulin*)

or C-section (*low cortisol*)

TX: *dexamethasone* before birth



Quiz Lung maturity determined with



ANS: Amniocentesis of Phospholipids (*type II pneumocytes)

L >> S



Quiz Type I pneumocytes



ANS: Squamous gas diffusion



Quiz Elastase in lungs



ANS: macrophage: *lysosomes*

PMN: *azuronphilic granules*



Quiz Elastin stretches and recoils due to



ANS: Lysine interchain crosslinks



Quiz air pressure and

intrapleural pressure at FRC

,ANS: Air pressure = 0

Intrapleural pressure = -5



Quiz Pulm Vasc Resistance is lowest during



ANS: Exhale of Tidal Volume



Quiz Lung Compliance is decreased by



ANS: LHF, pulmonary edema,

pulmonary fibrosis



Quiz Lung Compliance is increased by



ANS: emphysema, age



Quiz Obesity affects ERV and FRC



ANS: DECREASE

ERV & FRC



Quiz Blood flow/min (pulmonary v systemic)



ANS: pulmonary = systemic

, Quiz Anatomic pulmonary shunting



ANS: Bronchial circulation causes

*decreased PO2 in LA/LV*

than in pulmonary capillaries



Quiz More ventilation is at the



ANS: BASE



Quiz O2-Hgb dissociation LEFT shift



ANS: basic, cold, low 2,3 BPG

low pO2 (compensatory erythrocytosis)



Quiz O2-Hgb dissociation RIGHT shift



ANS: low pH, high 2,3BPG, high T

HOT, ACIDIC



Quiz CO2 transport to lungs



ANS: *carbonic anhydrase*

Cl shift

*Haldane*: CO2 released to lung