PlusBay.Plus
,TEST BANK FOR
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Immunology and Serology in Laboratory Medicine, 7th Edition by Mary Louise Turgeon
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Chapter 1-27
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Chapter 01: Highlights of the Innate and Adaptive Immune Systems
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MULTIPLE CHOICE mf
1. The ―father‖ of immunology is generally considered t o be
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a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: B m f
Louis Pasteur is generally considered to be the ―father of immunology.‖
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DIF: Cognitive Level: I mf mf
2. An early form of immunization was practiced by the
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a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans. mf
ANS: C m f
Beginning about 1000 AD, the Chinese practiced a form of immunization by inhaling dried po
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wders derived from the crusts of smallpox lesions.
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DIF: Cognitive Level: I mf mf
3. A specific function of the immune system is to
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a. recognize self from nonself. mf mf mf
b. defend the body against nonself. mf mf mf mf
c. amplify specific functions. mf mf
d. Both A and B. mf mf mf
ANS: D m f
The function of the immune system is to recognize self from nonself and defend the body agai
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nst nonself. Such a system is necessary for survival. The immune system also has nonspecific
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effector mechanisms that usually amplify the specific functions. Nonspecific components of t
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he immune system include mononuclear phagocytes, polymorphonuclear leukocytes, and solu
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ble factors (e.g., complement).
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DIF: Cognitive Level: I mf mf
4. An undesirable consequence of immunity is
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a. natural resistance. mf
b. acquired resistance to infectious diseases. mf mf mf mf
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, c. an autoimmune disorder.
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d. recovery from infectious disease. mf mf mf
ANS: C m f
The desirable consequences of immunity include natural resistance, recovery, and acquired re
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sistance to infectious diseases. A deficiency or dysfunction of the immune system can cause m
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any disorders. Undesirable consequences of immunity include allergy, rejection of a transplan
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ted organ, or an autoimmune disorder.
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DIF: Cognitive Level: I mf mf
5. The immune system has various distinctive characteristics except;
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a. specificity.
b. memory.
c. mobility.
d. noncooperation among different cells. mf mf mf
ANS: D m f
The immune system is composed of a large, complex set of widely distributed elements, with
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the distinctive characteristics of specificity, memory, mobility, replicability, and cooperation a
mf mf mf mf mf mf mf mf mf mf
mong different cells or cellular products. Specificity and memory are characteristics of lymph
mf mf mf mf mf mf mf mf mf mf mf mf
ocytes in the immune system. Nonspecific elements of the immune system demonstrate mobili
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ty. In addition, specific and nonspecific cellular components of the immune system can replica
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te. Cooperation is required for optimal functioning, and interaction involves specific cellular e
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lements, cell products, and nonlymphoid elements.
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DIF: Cognitive Level: I mf mf
6. Hematopoiesis occurs in the yolk sac during the mf mf mf mf mf mf mf
a. immediate hours after conception mf mf mf
b. second month of gestation. mf mf mf
c. second trimester of gestation. mf mf mf
d. periods of severe anemia in children. mf mf mf mf mf
ANS: A m f
The sites of blood cell development, or hematopoiesis, follow a definite sequence in the embr
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yo and fetus. Hematopoiesis occurs in the yolk sac during the second month of gestation.
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DIF: Cognitive Level: II mf mf
7. The sequence of blood cell development in the embryo and fetus is
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a. yolk sac, liver-spleen, bone marrow.
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b. yolk sac, bone marrow, liver/spleen.
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c. liver-spleen, yolk sac, bone marrow. mf mf mf mf
d. bone marrow, liver-spleen, yolk sac.
mf mf mf mf
ANS: A m f
PlusBay.Plus
, The first blood cells are primitive red blood cells (erythroblasts; RBCs) formed in the islets o
mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf
f the yolk sac during the first 2 to 8 weeks of life. Gradually, the liver and spleen replace the
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yolk sac as the sites of blood cell development. By the second month of gestation, the liver
mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf
becomes the major site of hematopoiesis, and granular types of leukocytes have made their i
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nitial appearance. The liver and spleen predominate from about 2 to 5 months of fetal life. In
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the fourth month of gestation, bone marrow begins to produce blood cells. After the fifth fet
mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf
al month, bone marrow begins to assume its ultimate role as the primary site of hematopoies
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is.
DIF: Cognitive Level: II mf mf
8. The primary function of mature neutrophils is
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a. to reduce inflammation. mf mf
b. to lyse parasites in the circulatory system.
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c. antigen recognition. mf
d. phagocytosis.
ANS: D m f
Various phagocytic cells continually circulate throughout the blood, lymph, gastrointestinal s
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ystem, and respiratory tract. When trauma occurs, the neutrophils arrive at the site of injury a
mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf
nd can be found in the initial exudate in less than 1 hour. Monocytes are slower in moving to t
mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf
he inflammatory site. Macrophages resident in the tissues of the body are already in place to
mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf
deal with an intruding agent. Additional macrophages from the bone marrow and other tissues
mf mf mf mf mf mf mf mf mf mf mf mf mf mf
can be released in severe infections.
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DIF: Cognitive Level: II mf mf
9. Primary granules, or azurophilic granules, in neutrophils contain
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a. lysozyme.
b. myeloperoxidase.
c. lactoferrin.
d. Both A and B. mf mf mf
ANS: D m f
Granules in the phagocyte cytosol contain degradatory enzymes of three types
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1. Primary, or azurophilic, granules containing enzymes (e.g., lysozyme, mf mf mf mf mf mf mf
myeloperoxidase) mf
2. Secondary, or specific, granules containing substances such as lactoferrin. mf mf mf mf mf mf mf mf
3. Tertiary granules containing substances such as caspases mf mf mf mf mf mf
DIF: Cognitive Level: I mf mf
10. The origin of a condition when eosinophils are increased in the circulating blood is associate
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d with:
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a. fungus
b. parasitic amoeba mf
c. allergic reactions mf
d. bacteria
ANS: C m f
PlusBay.Plus
,TEST BANK FOR
mf mf
Immunology and Serology in Laboratory Medicine, 7th Edition by Mary Louise Turgeon
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Chapter 1-27
mf
Chapter 01: Highlights of the Innate and Adaptive Immune Systems
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MULTIPLE CHOICE mf
1. The ―father‖ of immunology is generally considered t o be
mf mf mf mf mf mf mf mf
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: B m f
Louis Pasteur is generally considered to be the ―father of immunology.‖
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DIF: Cognitive Level: I mf mf
2. An early form of immunization was practiced by the
mf mf mf mf mf mf mf mf
a. Romans.
b. Greeks.
c. Chinese.
d. Native Americans. mf
ANS: C m f
Beginning about 1000 AD, the Chinese practiced a form of immunization by inhaling dried po
mf mf mf mf mf mf mf mf mf mf mf mf mf mf
wders derived from the crusts of smallpox lesions.
mf mf mf mf mf mf mf
DIF: Cognitive Level: I mf mf
3. A specific function of the immune system is to
mf mf mf mf mf mf mf mf
a. recognize self from nonself. mf mf mf
b. defend the body against nonself. mf mf mf mf
c. amplify specific functions. mf mf
d. Both A and B. mf mf mf
ANS: D m f
The function of the immune system is to recognize self from nonself and defend the body agai
mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf
nst nonself. Such a system is necessary for survival. The immune system also has nonspecific
mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf
effector mechanisms that usually amplify the specific functions. Nonspecific components of t
mf mf mf mf mf mf mf mf mf mf mf
he immune system include mononuclear phagocytes, polymorphonuclear leukocytes, and solu
mf mf mf mf mf mf mf mf mf
ble factors (e.g., complement).
mf mf mf
DIF: Cognitive Level: I mf mf
4. An undesirable consequence of immunity is
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a. natural resistance. mf
b. acquired resistance to infectious diseases. mf mf mf mf
PlusBay.Plus
, c. an autoimmune disorder.
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d. recovery from infectious disease. mf mf mf
ANS: C m f
The desirable consequences of immunity include natural resistance, recovery, and acquired re
mf mf mf mf mf mf mf mf mf mf mf
sistance to infectious diseases. A deficiency or dysfunction of the immune system can cause m
mf mf mf mf mf mf mf mf mf mf mf mf mf mf
any disorders. Undesirable consequences of immunity include allergy, rejection of a transplan
mf mf mf mf mf mf mf mf mf mf mf
ted organ, or an autoimmune disorder.
mf mf mf mf mf
DIF: Cognitive Level: I mf mf
5. The immune system has various distinctive characteristics except;
mf mf mf mf mf mf mf
a. specificity.
b. memory.
c. mobility.
d. noncooperation among different cells. mf mf mf
ANS: D m f
The immune system is composed of a large, complex set of widely distributed elements, with
mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf
the distinctive characteristics of specificity, memory, mobility, replicability, and cooperation a
mf mf mf mf mf mf mf mf mf mf
mong different cells or cellular products. Specificity and memory are characteristics of lymph
mf mf mf mf mf mf mf mf mf mf mf mf
ocytes in the immune system. Nonspecific elements of the immune system demonstrate mobili
mf mf mf mf mf mf mf mf mf mf mf mf
ty. In addition, specific and nonspecific cellular components of the immune system can replica
mf mf mf mf mf mf mf mf mf mf mf mf mf
te. Cooperation is required for optimal functioning, and interaction involves specific cellular e
mf mf mf mf mf mf mf mf mf mf mf mf
lements, cell products, and nonlymphoid elements.
mf mf mf mf mf
DIF: Cognitive Level: I mf mf
6. Hematopoiesis occurs in the yolk sac during the mf mf mf mf mf mf mf
a. immediate hours after conception mf mf mf
b. second month of gestation. mf mf mf
c. second trimester of gestation. mf mf mf
d. periods of severe anemia in children. mf mf mf mf mf
ANS: A m f
The sites of blood cell development, or hematopoiesis, follow a definite sequence in the embr
mf mf mf mf mf mf mf mf mf mf mf mf mf mf
yo and fetus. Hematopoiesis occurs in the yolk sac during the second month of gestation.
mf mf mf mf mf mf mf mf mf mf mf mf mf mf
DIF: Cognitive Level: II mf mf
7. The sequence of blood cell development in the embryo and fetus is
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a. yolk sac, liver-spleen, bone marrow.
mf mf mf mf
b. yolk sac, bone marrow, liver/spleen.
mf mf mf mf
c. liver-spleen, yolk sac, bone marrow. mf mf mf mf
d. bone marrow, liver-spleen, yolk sac.
mf mf mf mf
ANS: A m f
PlusBay.Plus
, The first blood cells are primitive red blood cells (erythroblasts; RBCs) formed in the islets o
mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf
f the yolk sac during the first 2 to 8 weeks of life. Gradually, the liver and spleen replace the
mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf
yolk sac as the sites of blood cell development. By the second month of gestation, the liver
mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf
becomes the major site of hematopoiesis, and granular types of leukocytes have made their i
mf mf mf mf mf mf mf mf mf mf mf mf mf mf
nitial appearance. The liver and spleen predominate from about 2 to 5 months of fetal life. In
mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf
the fourth month of gestation, bone marrow begins to produce blood cells. After the fifth fet
mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf
al month, bone marrow begins to assume its ultimate role as the primary site of hematopoies
mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf
is.
DIF: Cognitive Level: II mf mf
8. The primary function of mature neutrophils is
mf mf mf mf mf mf
a. to reduce inflammation. mf mf
b. to lyse parasites in the circulatory system.
mf mf mf mf mf mf
c. antigen recognition. mf
d. phagocytosis.
ANS: D m f
Various phagocytic cells continually circulate throughout the blood, lymph, gastrointestinal s
mf mf mf mf mf mf mf mf mf mf
ystem, and respiratory tract. When trauma occurs, the neutrophils arrive at the site of injury a
mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf
nd can be found in the initial exudate in less than 1 hour. Monocytes are slower in moving to t
mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf
he inflammatory site. Macrophages resident in the tissues of the body are already in place to
mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf mf
deal with an intruding agent. Additional macrophages from the bone marrow and other tissues
mf mf mf mf mf mf mf mf mf mf mf mf mf mf
can be released in severe infections.
mf mf mf mf mf
DIF: Cognitive Level: II mf mf
9. Primary granules, or azurophilic granules, in neutrophils contain
mf mf mf mf mf mf mf
a. lysozyme.
b. myeloperoxidase.
c. lactoferrin.
d. Both A and B. mf mf mf
ANS: D m f
Granules in the phagocyte cytosol contain degradatory enzymes of three types
mf mf mf mf mf mf mf mf mf mf
1. Primary, or azurophilic, granules containing enzymes (e.g., lysozyme, mf mf mf mf mf mf mf
myeloperoxidase) mf
2. Secondary, or specific, granules containing substances such as lactoferrin. mf mf mf mf mf mf mf mf
3. Tertiary granules containing substances such as caspases mf mf mf mf mf mf
DIF: Cognitive Level: I mf mf
10. The origin of a condition when eosinophils are increased in the circulating blood is associate
mf mf mf mf mf mf mf mf mf mf mf mf mf mf
d with:
mf
a. fungus
b. parasitic amoeba mf
c. allergic reactions mf
d. bacteria
ANS: C m f
PlusBay.Plus