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CEN Respiratory Questions 2025/2026 – 100+ Exam-Based Q&A with Rationales | Pneumonia, Pulmonary Edema, Emphysema, Asthma, ABG, Ventilation, CO₂ Tension, Bronchodilators & Oxygenation

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This advanced emergency nursing resource delivers over 100 respiratory-focused CEN questions and correct answers, tailored for the Certified Emergency Nurse (CEN) exam 2025/2026. Each question comes with a clear, clinical rationale grounded in pathophysiology, evidence-based practice, and emergency protocols, ensuring comprehensive mastery of respiratory care concepts. Topics include: Acute & Chronic Pulmonary Conditions: Pneumonia, emphysema, pulmonary embolism, asthma exacerbations, bronchitis, and pulmonary edema Emergency Assessment & Intervention: Tripod positioning, barrel chest, peak expiratory flow rate, auscultation findings (crackles, vesicular sounds, wheezes) Oxygenation & Ventilation Physiology: Negative pressure mechanics, diffusion vs. perfusion, surfactant function, CO₂ shifts on the oxygen dissociation curve Respiratory Medications: Albuterol, prednisone, magnesium sulfate, theophylline, racemic epinephrine, ipratropium, heliox, morphine sulfate, low-molecular-weight heparin Respiratory Diagnostics & Prioritization: ABGs, capnography (ETCO₂), peak flow, auscultation placement, pneumonia core measures, pneumothorax signs Special Cases: Pediatric airway emergencies, carbon monoxide poisoning, aspiration, chronic bronchitis complications, asthma triggers This document is designed for advanced practice, exam preparation, and clinical reinforcement. It’s ideal for reviewing the full scope of respiratory emergencies that appear on the CEN exam and aligns closely with BCEN guidelines. Recommended for: Courses: Emergency Nursing, Respiratory Pathophysiology, Pulmonary Emergencies, Advanced Medical-Surgical Nursing Programs: BCEN CEN Certification Prep, Emergency Department Orientation, Critical Care Residency Users: CEN exam candidates, emergency nurses, nurse educators, advanced nursing students, EMS professionals entering hospital care Keywords: CEN 2025, respiratory emergencies, pulmonary embolism, pneumonia symptoms, ABG interpretation, peak flow rate, emphysema, asthma attack treatment, bronchial sounds, vesicular breath sounds, oxygen dissociation curve, CO2 tension, pulmonary edema, CPAP, diuretics, ETCO2, capnography, magnesium sulfate, racemic epinephrine, bronchodilator medications

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CEN RESPIRATORY QUESTIONS
2025/2026 EXAM QUESTIONS AND
ANSWERS | 100% PASS



Which respiratory emergency presents with fever, cough, pleuritic chest pain, and

crackles that do not clear with coughing?

Asthma, pulmonary edema, chronic bronchitis OR Pneumonia - 🧠ANSWER

✔✔Pneumonia


Pneumonia presents with fever, cough, pleuritic chest pain, and lung sounds (such

as crackles) that do not usually clear with coughing..

Which respiratory emergency causes permanent abnormal enlargement of the air

spaces?

Asthma, pulmonary edema, emphysema, pulmonary embolus - 🧠ANSWER

✔✔Emphysema


Patients with emphysema have a permanent, abnormal enlargement of air spaces.

,Asthma, pulmonary edema, and pulmonary embolus do not result in permanent

alveolar changes.

A woman, age 53, presents to the emergency department with shortness of breath.

Which other finding should make you suspect that pulmonary embolism is the

cause?


Tachypnea, productive cough, calf pain, pleuritic chest pain - 🧠ANSWER ✔✔Calf

pain for the past week




Most pulmonary emboli originate in the deep veins of the legs, which could cause

prolonged calf pain.




Tachypnea, productive cough, and pleuritic chest pain are common, nonspecific

signs and symptoms of many respiratory conditions.

A man, age 72, presents to the emergency department with respiratory distress. He

arrived with portable oxygen from home and is now sitting in a tripod position.

Your assessment reveals a barrel chest. Which respiratory condition should you

suspect?

, Pulmonary embolism, asthma, emphysema, acute bronchitis - 🧠ANSWER

✔✔Emphysema




Barrel chest, home oxygen therapy, and the use of the tripod position are classic

presentations in a patient with emphysema. Pulmonary embolism, asthma, and

acute bronchitis are not associated with these findings.

Which statement best defines ventilation?

Ventilation is the

1. mechanical flow of air into and out of the lungs.

2. mechanical perfusion of air into and out of the lungs

3. mechanical respiration of air into and out of the lungs

4. mechanical diffusion of air into and out of the lungs - 🧠ANSWER

✔✔Ventilation is the mechanical flow of air into and out of the lungs.




Negative intrathoracic pressure causes a vacuum effect, pulling air into the lungs

during inspiration. During expiration, the negative pressure decreases and air is


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