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B1 - ANSWER:Thiamin
thiamin dietary sources - ANSWER:pork, whole grains, enriched grains, legumes
B1 coenzyme - ANSWER:Thiamin diphosphate ThDP
Thiamin RDA - ANSWER:1.1-1.2 mg/day
Thiamin deficiency - ANSWER:Beriberi, PDH deficiency, maple syrup urine
B2 - ANSWER:Riboflavin
B2 coenzyme - ANSWER:FAD and FMN
Riboflavin RDA - ANSWER:Men: 1.3 mg/day
,Women: 1.1 mg/day
Riboflavin deficiency - ANSWER:ariboflavinosis - cracks and redness of the lips
and corners of the mouth, swelling of the mouth and sore throat
Impacts lipid metabolism
riboflavin dietary sources - ANSWER:milk/milk products, enriched grains, meat,
leafy greens
Riboflavin redox reduction 4 rxn - ANSWER:
1. Oxidative decarboxylation of pyruvate and alpha KG
2. Succinate dehydrogenase
3. Acyl co A dehydrogenase
4. L amino to imino by FMN
Riboflavin also used for - ANSWER:DNA replication and repair
- synthesis of PLP
Synthesis of 5 methyl THF
B3 - ANSWER:Niacin
, The three niacin vitamers - ANSWER:Nicotinic acid: treat dyslipidemia by
inhibiting lipolysis
Nicotinamide: treat harnup disease: Bo transporter of tryptophan
Nicotinamide riboside
Niacin coenzyme - ANSWER:NAD and NADP(h)
Niacin RDA - ANSWER:14-16 mg/day
Niacin UL - ANSWER:Adults: 35 mg/day prevent niacin flush
Niacin deficiency - ANSWER:pellagra: dermatitis, diarrhea, dementia, death
Niacin diet - ANSWER:Plant and animal
NAD other things - ANSWER:- Used as substrate for rxn linked to DNA repair
(PARP)
- life extension (sitruins)
B7 - ANSWER:Biotin
RDA for biotin - ANSWER:30 ug/day