1|Page
,Chapter 1: An Introduction to Physiology
1. A patient presents with dehydration. Which body system plays a key role in regulating
water balance in the body?
a) Nervous system
b) Endocrine system
c) Urinary system
d) Cardiovascular system
Answer:
c) Urinary system
Rationale:
The urinary system, particularly the kidneys, plays a vital role in regulating water balance
by filtering blood and eliminating excess fluids and waste. The kidneys respond to
hormones that help maintain fluid balance.
NCLEX Focus: Physiological Adaptation - Fluid and Electrolyte Imbalance
2. During a physical examination, the nurse checks the patient’s reflexes. This assessment
primarily involves which body system?
a) Respiratory system
b) Muscular system
c) Nervous system
d) Endocrine system
Answer:
c) Nervous system
Rationale:
The nervous system is responsible for controlling reflex actions through the interaction
between sensory and motor neurons. Reflex testing helps evaluate the function of the
nervous system.
NCLEX Focus: Physiological Integrity - Neurosensory System
3. A patient with high blood pressure is being treated with medications that affect heart rate
and blood vessel dilation. These medications are primarily targeting which system?
a) Digestive system
b) Cardiovascular system
c) Endocrine system
d) Respiratory system
Answer:
b) Cardiovascular system
Rationale:
The cardiovascular system controls blood pressure through heart rate and blood vessel
resistance. Medications for hypertension target the heart and blood vessels to reduce
pressure.
NCLEX Focus: Pharmacological Therapies - Cardiovascular System
4. Which process is an example of positive feedback that a nurse may observe during labor
and delivery?
a) Blood clotting
b) Uterine contractions
2|Page
, c) Thermoregulation
d) Regulation of blood glucose
Answer:
b) Uterine contractions
Rationale:
Positive feedback amplifies a response to achieve a specific outcome. During labor,
uterine contractions increase in intensity and frequency until childbirth occurs, a classic
example of positive feedback.
NCLEX Focus: Health Promotion and Maintenance - Reproductive System
5. A nurse explains to a patient that normal body temperature is maintained through which
feedback mechanism?
a) Positive feedback
b) Negative feedback
c) Hormonal regulation
d) Immune response
Answer:
b) Negative feedback
Rationale:
Negative feedback mechanisms regulate body temperature by initiating responses to cool
down or heat up the body when deviations from normal temperature occur.
NCLEX Focus: Physiological Adaptation - Thermoregulation
6. A patient undergoing surgery is at risk for impaired oxygen delivery to tissues. Which
organ system is primarily responsible for transporting oxygen in the body?
a) Respiratory system
b) Cardiovascular system
c) Endocrine system
d) Digestive system
Answer:
b) Cardiovascular system
Rationale:
The cardiovascular system, through blood circulation, transports oxygen from the lungs
to tissues. Red blood cells carry oxygen, which is essential for cellular function.
NCLEX Focus: Physiological Integrity - Oxygenation
7. During an infection, which system is most responsible for defending the body against
pathogens?
a) Cardiovascular system
b) Integumentary system
c) Lymphatic system
d) Nervous system
Answer:
c) Lymphatic system
Rationale:
The lymphatic system plays a central role in immune defense, filtering pathogens and
producing immune cells like lymphocytes that help fight infections.
NCLEX Focus: Physiological Integrity - Immune System
3|Page
, 8. A nurse is caring for a patient who is losing heat rapidly due to hypothermia. Which
process will the body most likely use to attempt to restore normal temperature?
a) Positive feedback
b) Negative feedback
c) Immune response
d) Hormonal secretion
Answer:
b) Negative feedback
Rationale:
Negative feedback mechanisms will work to increase body temperature through shivering
and constricting blood vessels to conserve heat.
NCLEX Focus: Physiological Adaptation - Thermoregulation
9. After a meal, the body begins the process of breaking down carbohydrates for energy.
Which life process is this?
a) Metabolism
b) Growth
c) Differentiation
d) Reproduction
Answer:
a) Metabolism
Rationale:
Metabolism includes the chemical processes involved in breaking down food molecules
to produce energy. This is crucial for all body activities.
NCLEX Focus: Physiological Integrity - Metabolism
10. A patient with diabetes is unable to regulate blood glucose levels effectively. This patient
has an impairment in which process?
a) Growth
b) Homeostasis
c) Reproduction
d) Movement
Answer:
b) Homeostasis
Rationale:
Homeostasis refers to the body's ability to maintain stable internal conditions, such as
blood glucose levels, through feedback mechanisms. In diabetes, this regulation is
impaired.
NCLEX Focus: Physiological Adaptation - Endocrine System
11. A patient experiences a sudden drop in blood pressure. What immediate feedback
mechanism does the body use to stabilize blood pressure?
a) Positive feedback
b) Negative feedback
c) Neutral feedback
d) Metabolic feedback
Answer:
b) Negative feedback
Rationale:
4|Page
,Chapter 1: An Introduction to Physiology
1. A patient presents with dehydration. Which body system plays a key role in regulating
water balance in the body?
a) Nervous system
b) Endocrine system
c) Urinary system
d) Cardiovascular system
Answer:
c) Urinary system
Rationale:
The urinary system, particularly the kidneys, plays a vital role in regulating water balance
by filtering blood and eliminating excess fluids and waste. The kidneys respond to
hormones that help maintain fluid balance.
NCLEX Focus: Physiological Adaptation - Fluid and Electrolyte Imbalance
2. During a physical examination, the nurse checks the patient’s reflexes. This assessment
primarily involves which body system?
a) Respiratory system
b) Muscular system
c) Nervous system
d) Endocrine system
Answer:
c) Nervous system
Rationale:
The nervous system is responsible for controlling reflex actions through the interaction
between sensory and motor neurons. Reflex testing helps evaluate the function of the
nervous system.
NCLEX Focus: Physiological Integrity - Neurosensory System
3. A patient with high blood pressure is being treated with medications that affect heart rate
and blood vessel dilation. These medications are primarily targeting which system?
a) Digestive system
b) Cardiovascular system
c) Endocrine system
d) Respiratory system
Answer:
b) Cardiovascular system
Rationale:
The cardiovascular system controls blood pressure through heart rate and blood vessel
resistance. Medications for hypertension target the heart and blood vessels to reduce
pressure.
NCLEX Focus: Pharmacological Therapies - Cardiovascular System
4. Which process is an example of positive feedback that a nurse may observe during labor
and delivery?
a) Blood clotting
b) Uterine contractions
2|Page
, c) Thermoregulation
d) Regulation of blood glucose
Answer:
b) Uterine contractions
Rationale:
Positive feedback amplifies a response to achieve a specific outcome. During labor,
uterine contractions increase in intensity and frequency until childbirth occurs, a classic
example of positive feedback.
NCLEX Focus: Health Promotion and Maintenance - Reproductive System
5. A nurse explains to a patient that normal body temperature is maintained through which
feedback mechanism?
a) Positive feedback
b) Negative feedback
c) Hormonal regulation
d) Immune response
Answer:
b) Negative feedback
Rationale:
Negative feedback mechanisms regulate body temperature by initiating responses to cool
down or heat up the body when deviations from normal temperature occur.
NCLEX Focus: Physiological Adaptation - Thermoregulation
6. A patient undergoing surgery is at risk for impaired oxygen delivery to tissues. Which
organ system is primarily responsible for transporting oxygen in the body?
a) Respiratory system
b) Cardiovascular system
c) Endocrine system
d) Digestive system
Answer:
b) Cardiovascular system
Rationale:
The cardiovascular system, through blood circulation, transports oxygen from the lungs
to tissues. Red blood cells carry oxygen, which is essential for cellular function.
NCLEX Focus: Physiological Integrity - Oxygenation
7. During an infection, which system is most responsible for defending the body against
pathogens?
a) Cardiovascular system
b) Integumentary system
c) Lymphatic system
d) Nervous system
Answer:
c) Lymphatic system
Rationale:
The lymphatic system plays a central role in immune defense, filtering pathogens and
producing immune cells like lymphocytes that help fight infections.
NCLEX Focus: Physiological Integrity - Immune System
3|Page
, 8. A nurse is caring for a patient who is losing heat rapidly due to hypothermia. Which
process will the body most likely use to attempt to restore normal temperature?
a) Positive feedback
b) Negative feedback
c) Immune response
d) Hormonal secretion
Answer:
b) Negative feedback
Rationale:
Negative feedback mechanisms will work to increase body temperature through shivering
and constricting blood vessels to conserve heat.
NCLEX Focus: Physiological Adaptation - Thermoregulation
9. After a meal, the body begins the process of breaking down carbohydrates for energy.
Which life process is this?
a) Metabolism
b) Growth
c) Differentiation
d) Reproduction
Answer:
a) Metabolism
Rationale:
Metabolism includes the chemical processes involved in breaking down food molecules
to produce energy. This is crucial for all body activities.
NCLEX Focus: Physiological Integrity - Metabolism
10. A patient with diabetes is unable to regulate blood glucose levels effectively. This patient
has an impairment in which process?
a) Growth
b) Homeostasis
c) Reproduction
d) Movement
Answer:
b) Homeostasis
Rationale:
Homeostasis refers to the body's ability to maintain stable internal conditions, such as
blood glucose levels, through feedback mechanisms. In diabetes, this regulation is
impaired.
NCLEX Focus: Physiological Adaptation - Endocrine System
11. A patient experiences a sudden drop in blood pressure. What immediate feedback
mechanism does the body use to stabilize blood pressure?
a) Positive feedback
b) Negative feedback
c) Neutral feedback
d) Metabolic feedback
Answer:
b) Negative feedback
Rationale:
4|Page
