LEHNE’S PHARMACOTHERAPEUTICS FOR ADVANCED PRACTICE
NURSES AND PHYSICIAN ASSISTANTS
LAURA D. ROSENTHAL, AND JACQUELINE ROSENJACK
BURCHUM
2nd43Edition
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,Table43of43Contents
Unit430143Introduction 1
Unit430243Basic43Principles43of43Pharmacology 6
Unit430343Drug43Therapy43Across43the43Life43Span 15
Unit430443Peripheral43Nervous43System43Drugs 22
Unit430543Central43Nervous43System43Drugs 31
Unit430643Drugs43for43Pain 38
Unit430743Psychotherapeutic43Drugs 43
Unit430843Substance43Use43Disorders 51
Unit430943Drugs43That43Affect43the43Heart,43Blood43Vessels,43Blood,43and43Blood43Volume 59
Unit431043Drugs43for43Endocrine43Disorders 68
Unit431143Women’s43Health 73
Unit431243Men’s43Health 78
Unit431343Antiinflammatory,43Antiallergic,43and43Immunologic43Drugs 83
Unit431443Drugs43for43Bone43and43Joint43Disorders 91
Unit431543Respiratory43Tract43Drugs 97
Unit431643Gastrointestinal43Drugs 102
Unit431743Nutrition43and43Complimentary43Therapies 110
Unit431843Therapy43of43Infectious43and43Parasitic43Diseases 116
Unit431943Cancer43Therapy 140
Unit432043Drugs43for43Eyes,43Ears,43and43Skin 145
Unit432143Drugs43Therapy43in43Acute43Care 152
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,Test43Bank43-
43Lehne’s43Pharmacotherapeutics43for43Advanced43Practice43Nurses43&43Physician43Assistants,432e43(Rosenthal,432
021) Unit4301:43Introduction
Rosenthal:43Lehne's43Pharmacotherapeutics43for43Advanced43Practice43Nurses43and43Ph
ysician43Assistants,432nd43Edition
MULTIPLE43CHOICE
1. A43patient43diagnosed43with43chronic43pain43calls43to43request43an43oxycodone43(Oxyco
ntin)43refill.43Which43action43should43the43prescriber43take43initially?
a. Fax43the43renewal43order43to43the43pharmacy.
b. Arrange43to43schedule43an43appointment43with43the43patient.
c. Verify43the43patient’s43adherence43to43the43prescribed43drug43regimen.
d. Determine43the43patient’s43current43medication43dosage43and43pain43level.
ANS:4 3 B
Schedule43II43medications43are43not43eligible43for43refills,43and43prescriptions43must43be43han
dwritten.43It43is43important43to43verify43the43patient’s43adherence43to43the43drug43regimen43a
nd43determine43the43current43dosage43of43medication43and43pain43level;43however,43this43ca
n43be43accomplished43by43scheduling43an43appointment43and43evaluating43the43patient43in43
person.
2. A43metered-
dose43albuterol43inhaler43is43prescribed43for43asthma43management.43The43patient43reports43
feeling43jittery43sometimes43when43taking43the43medication,43and43does43not43feel43that43the
43medication43is43always43effective.43Which43action43will43the43provider43take43to43best43
minimize43patient43risks43and43maximize43medication43effectiveness?
a. Ask43the43patient43to43demonstrate43use43of43the43inhaler43and43assess43effectiveness.
b. Assess43the43patient’s43exposure43to43first-43and43second-hand43tobacco43smoke.
c. Auscultate43the43patient's43l43un43W
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in43other43relevant43vital43signs.
d. Decrease43the43dosage43to43reduce43side43effects.
ANS:4 3 C
Assessing43and43evaluating43lung43sounds43as43well43as43other43vital43signs43helps43determi
ne43the43patient's43physical43response43to43the43medication43and43allows43comparison43to43th
e43patient's43baseline43vital43signs.43Asking43the43patient43to43demonstrate43inhaler43use43hel
ps43to43evaluate43the43patient’s43ability43to43administer43the43medication43properly43and43is43
part43of43an43effective43evaluation,43but43is43not43a43priority43intervention43based43on43the43p
atient’s43current43report.43Assessing43tobacco43smoke43exposure43helps43determine43whethe
r43nondrug43therapies,43such43as43smoke43avoidance,43can43be43used43as43an43adjunct43to43dru
g43therapy,43but43does43not43relate43to43the43patient’s43current43problem.43Rewriting43the43pr
escription43to43decrease43the43dosage43may43address43the43degree43of43jitteriness43experienc
ed,
but43does43not43address43the43patient’s43concern43that43the43drug43is43not43always43effective.
3. A43patient43is43prescribed43metronidazole43for43bacterial43vaginosis.43Which43patient43histo
ry43finding43would43be43most43concerning43to43the43provider?
a. The43patient43had43a43recent43yeast43infection.
b. There43is43a43family43history43of43cervical43cancer.
c. The43patient43drinks43two43glasses43of43wine43every43night.
d. The43patient43is43unemploy
ed.43ANS:4 3 C
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43Lehne’s43Pharmacotherapeutics43for43Advanced43Practice43Nurses43&43Physician43Assistants,432e43(Rosenthal,432
021) Patients43taking43metronidazole43should43be43educated43not43to43drink43alcohol43to43prevent
43a43disulfiram-
like43reaction.43It43would43be43concerning43that43the43patient43drinks43wine43daily.43History
43of43a43yeast43infection43may43indicate43increased43risk43for43recurrence43with43administrat
ion43of43an43antimicrobial.43A43family43history43of43cervical43cancer43is43not43related43to43a
dministration43of43metronidazole.43Unemployment43can43indicate43lack43of43insurance43cove
rage,43which43may43limit43the43patient’s43ability43to43purchase43medications;43however,43ge
neric43metronidazole43is43one43of43the43less43expensive43medications.
4. The43provider43prepares43a43patient43with43newly43diagnosed43type43143diabetes43for43hospita
l43discharge.43Which43action43by43the43provider43will43best43support43the43patient’s43ability4
3to43effectively43manage43medication43therapy?
a. Asking43the43patient43to43demonstrate43how43to43measure43and43administer43insulin
b. Discussing43methods43of43storing43insulin43and43discarding43syringes
c. Giving43information43about43how43diet43and43exercise43affect43insulin43requirements
d. Teaching43the43patient43about43the43long-term43consequences43of43poor43diabetes43control
ANS:4 3 A
Because43insulin43must43be43given43correctly43to43control43symptoms43and43prevent43an43ove
rdose,43it43is43most43important43for43the43patient43to43know43how43to43measure43and43admini
ster43it.43Asking43for43a43demonstration43of43technique43is43the43best43way43to43determine43w
hether43the43patient43has43understood43the43teaching.43The43other43teaching43points43are43im
portant43as43well,43but43they43are43not43as43critical.
5. A43patient43reports43that43a43medication43prescribed43for43recurrent43migraine43headache
s43is43not43working.43Which43action43is43the43prescriber’s43priority43when43addressing43th
e43patient's43concern?
a. Ask43the43patient43about43the43number43and43frequency43of43tablets43taken.
b. Assess43the43patient’s43headache43pain43on43a43scale43from43143to4310.
c. Prescribe43a43new43medicationWfW
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mWanSagement.
d. Suggest43biofeedback43as43an43adjunct43to43drug43therapy.
ANS:4 3 A
When43evaluating43the43effectiveness43of43a43drug,43it43is43important43to43determine43how4
3often43the43patient43is43using43the43drug.43Asking43the43patient43to43identify43how43many43t
ablets43are43taken43and43how43often43helps43the43provider43determine43effective43dosages43
and43adherence43to43the43medication43regimen.43The43patient43has43already43stated43that43th
e43medication43is43not43working;43the43actual43level43of43pain43may43determine43the43degre
e43to43which43it43is43not43working,43but43it43does43not43help43the43provider43to43determine43
why43it43is43not43working.43The43assessment43process43should43gather43as43much43informati
on43about43compliance,43symptoms,43and43drug43effectiveness43as43possible43before43enact
ing43a43change43in43treatment.43Biofeedback43may43be43an43effective43adjunct43to43treatment
,43but43it43should43not43be43recommended43without43complete43information43about43drug43e
ffectiveness.
6. The43drug43manual43states43that43older43adult43patients43are43at43increased43risk43for43hepat
otoxicity.43Which43action43is43most43important43when43prescribing43this43medication43to43an
4380-year-old43patient?
a. Obtaining43baseline43liver43function43studies
b. Ensuring43that43the43drug43is43taken43in43the43correct43dose43at43the43correct43time
c. Discontinuing43the43order;43the43drug43is43contraindicated43for43this43patient
d. Giving43the43medication43intravenously43to43avoid43first43pass43met
abolism43ANS:4 3 A
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