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Exam (elaborations)

Understanding Pathophysiology – 7th Edition, Huether & McCance – Complete Test Bank with NCLEX-Style Questions and Rationales

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This comprehensive test bank is based on Understanding Pathophysiology (7th Edition) by Sue E. Huether and Kathryn L. McCance. It contains NCLEX-style multiple-choice questions and answers with rationales, organized by body systems and disease mechanisms. Key topics include cellular function, inflammation, immunity, genetic disorders, cancer biology, and pathophysiologic processes across all organ systems. Ideal for nursing and allied health students preparing for exams or mastering complex concepts in pathophysiology.

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Institution
Pathophysiology
Course
Pathophysiology











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Institution
Pathophysiology
Course
Pathophysiology

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Uploaded on
July 8, 2025
Number of pages
885
Written in
2024/2025
Type
Exam (elaborations)
Contains
Questions & answers

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Test Bank Understanding Pathophysiology 7th Edition




Chapter 01: Cellular Biology

Test Bank Page 1

, Test Bank Understanding Pathophysiology 7th Edition
Huether & McCance: Understanding Pathophysiology, 7th Edition



MULTIPLE CHOICES


1. A student is observing a cell under the microscope. It is observed to have supercoiled DNAwi
P




th histones. Which of the following would also be observed by the student?
a. A single circular chromosome
b. A nucleus
c. Free-floating nuclear material
d. No organelles

ANS: B
The cell described is a eukaryotic cell, so it has histones and a supercoiled DNA within itsnu
P




cleus; thus, the nucleus should be observed. A single circular chromosome called a prokary
ote contains free-floating nuclear material but has no organelles.


REF: p. 2


2. A nurse is instructing the staff about cellular functions. Which cellular function is the nurse de
scribing when an isolated cell absorbs oxygen and uses it to transform nutrients to energy?
a. Metabolic absorption
b. Communication
c. Secretion
d. Respiration

ANS: D




Test Bank Page 2

, Test Bank Understanding Pathophysiology 7th Edition
The cell’s ability to absorb oxygen is referred to as respiration while its communication abilityin
volves maintenance of a steady dynamic state, metabolic absorption provides nutrition, and secr
P P




etion allows for the synthesizing of new substances.
P




REF: p. 2


3. A eukaryotic cell is undergoing DNA replication. In which region of the cell would most ofth
e genetic information be contained?
P




a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm

ANS: C
The region of the cell that contains genetic material, including a large amount of ribonucleicac
P




id, most of the DNA, and DNA-
P




binding proteins, is the nucleolus, which is located withinthe cell’s nucleus. Mitochondria is a
ssociated with cellular respiration, while ribosomes are involved with protein manufacturing.
Cytoplasm is a fluid filling that is a component of the cell.
P




REF: p. 2

4. Which of the following can remove proteins attached to the cell’s bilayer by dissolving thela
P




yer itself?
a. Peripheral membrane proteins
b. Integral membrane proteins
c. Glycoproteins
d. Cell adhesion molecules

ANS: B
Proteins directly attached to the membrane bilayer can be removed by the action of integralme
P P




mbrane proteins that dissolve the bilayer. Peripheral membrane proteins reside at the surface
while cell adhesion molecules are on the outside of the membrane. Glycoprotein marks cells a
nd does not float.


REF: p. 7


5. Which of the following can bind to plasma membrane receptors?
P




Test Bank Page 3

, Test Bank Understanding Pathophysiology 7th Edition
a. Oxygen
b. Ribosomes
c. Amphipathic lipids
d. Ligands

ANS: D
Ligands are the only specific molecules that can bind with receptors on the cell membrane.
P




REF: p. 9


6. A nurse is reviewing a report from a patient with metastatic cancer. What alternation in theex
P P




tracellular matrix would s uNppUoRrtSthIeNdG
ia T
gnBo.
si C
s o f Mmetastatic cancer?
P




a. Decreased fibronectinP



b. Increased collagen
c. Decreased elastin P



d. Increased glycoproteins
P




ANS: A
Only a reduced amount of fibronectin is found in some types of cancerous cells, allowingth
em to travel or metastasize.


REF: p. 10


7. Which form of cell communication is used to relate to other cells in direct physical contact?
P



a. Cell junction
b. Gap junction
c. Desmosome
d. Tight junction
P




ANS: A
Cell junctions hold cells together and permit molecules to pass from cell to cell.
Gap junctions allow for cellular communication between cells. Neither desmosomes nor tightju
P




nctions are associated with cellular communication.


REF: p. 11




Test Bank Page 4

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