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Exam (elaborations)

2025 HESI RN Pharmacology Exam Version 3 (V3) – 3 Set Exams with NGN Style Qs & Case Studies (2025/2026)

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This resource contains three full sets of the HESI RN Pharmacology Exam Version 3, with a total of over 100 verified multiple-choice and NGN-style questions. Each exam integrates case-based scenarios, clinical judgment exercises, and expert rationales, covering key pharmacologic principles across drug classes including antihypertensives, antidiabetics, antibiotics, CNS agents, and more. The questions follow the 2025 NCLEX-RN blueprint and Next Generation NCLEX (NGN) formatting to help students improve clinical reasoning and exam performance.

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HESI RN
PHARMACOLOGY
V3 EXAM
(3 Set Exams)
(NGN style Qs & Case studies)
Actual Qs & Ans to Pass the
Exam

This hesi test contains:
 passing score Guarantee
 Each Exam has 55 Ques and Ans
 Format Set of Multiple-choice
 questions with incorporating Next
Generation NCLEX (NGN) and Case
studies questions
 Expert-Verified Explanations &
Solutions

, Contents
HESI RN PHARMACOLOGY V3 EXAM..................2
SET 1................................................................................. 2
HESI RN PHARMACOLOGY V3 EXAM................41
SET 2............................................................................... 41
HESI RN PHARMACOLOGY V3 EXAM................78
SET 3............................................................................... 78

,HESI RN PHARMACOLOGY V3 EXAM

SET 1
───────────────────────────────────────────────
───────
1) CASE STUDY (NGN-Style Question)
───────────────────────────────────────────────
─────────
Q1. A 54-year-old client with hypertension (HTN) and type 2 diabetes
mellitus (T2DM) is preparing to take the first dose of captopril. His daily
medications include spironolactone 25 mg/day, metformin 500 mg twice a
day, and insulin glargine 25 units daily. The nurse outlines several
instructions:

, • Instruction 1: Increase the insulin glargine dose by 3 units on the morning
of the first dose.
• Instruction 2: Limit fluids for several days before the first dose.
• Instruction 3: Lie down if blood pressure drops quickly after the first dose.
• Instruction 4: Monitor blood pressure for several hours after the first dose.
• Instruction 5: Hold spironolactone for 3 days prior to the first dose.


Question: For each nursing instruction below, indicate if it is Indicated
(safe/appropriate) or Contraindicated (unsafe/inappropriate) for a client
starting captopril.


A. 1 and 2 are Indicated; 3, 4, 5 are Contraindicated
B. 1, 2, 5 are Contraindicated; 3, 4 are Indicated
C. 1, 4 are Indicated; 2, 3, 5 are Contraindicated
D. 3, 5 are Indicated; 1, 2, 4 are Contraindicated


ANSWER: B (Instructions #1, #2, #5 = Contraindicated; Instructions #3,
#4 = Indicated)


Expert-Verified Explanation:
• Instruction 1 (increasing insulin without proven need) is contraindicated.
• Instruction 2 (limiting fluids pre–first-dose ACE inhibitor) is
contraindicated: risk of dehydration and severe hypotension.

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