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APEA 3P Exam Test Bank 2025/2026 | 150 Questions & Detailed Rationales | HealthStudyPro | Patho, Pharm, Physical Assessment

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APEA 3P Exam Test Bank 2025/2026 – This comprehensive study resource contains 150 high-yield questions with verified answers and detailed rationales across the essential “3P” topics: Pathophysiology, Pharmacology, and Physical Assessment. Perfect for NP students preparing for the APEA 3P Predictor Exam, board certification (AANP/ANCC), or core advanced practice nursing courses. Topics Covered: Advanced Pathophysiology (Cardiac, Neuro, Endocrine, Renal, GI, Heme) Pharmacology (Mechanisms, Adverse Effects, Drug Classes) Physical Assessment (Head-to-Toe, Pediatrics, Geriatrics, Clinical Signs) Supports popular NP textbooks: Seidel’s Guide to Physical Examination (Ball) Understanding Pathophysiology (Huether & McCance) Pharmacology for Primary Care Providers (Edmunds & Mayhew)

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APEA 3P Exam Test Bank 2025/2026 | 150 Questions &

Detailed Rationales | HealthStudyPro | Patho, Pharm,

Physical Assessment



✅ Question 001

A patient presents with left-sided facial droop, inability to close the left eye, and no forehead

sparing. Which cranial nerve is most likely affected?


A. Trigeminal nerve (CN V)

B. Facial nerve (CN VII)

C. Oculomotor nerve (CN III)

D. Glossopharyngeal nerve (CN IX)


Correct Answer: B

Rationale: The facial nerve (CN VII) controls facial muscle movement. A complete left-sided

facial droop including the forehead suggests a peripheral CN VII palsy (e.g., Bell's palsy).

,✅ Question 002

Which medication is contraindicated in a patient taking lisinopril and presenting with bilateral

lower extremity swelling?


A. Furosemide

B. Losartan

C. Amlodipine

D. Hydrochlorothiazide


Correct Answer: C

Rationale: Amlodipine, a calcium channel blocker, commonly causes peripheral edema. Using it

with an ACE inhibitor like lisinopril may worsen edema.




✅ Question 003

A 70-year-old male presents with new onset hematuria, flank pain, and a palpable abdominal

mass. Which diagnosis should be ruled out first?


A. Nephrolithiasis

B. Urinary tract infection

C. Renal cell carcinoma

D. Bladder cancer

,Correct Answer: C

Rationale: Classic triad of renal cell carcinoma includes hematuria, flank pain, and palpable

mass. This should be ruled out urgently.




✅ Question 004

Which of the following insulin types has the fastest onset of action?


A. Regular insulin

B. NPH insulin

C. Lispro (Humalog)

D. Glargine (Lantus)


Correct Answer: C

Rationale: Lispro is a rapid-acting insulin with onset within 15 minutes, making it the fastest

among options listed.




✅ Question 005

You suspect appendicitis in a 24-year-old male. Which physical exam finding supports your

diagnosis?


A. Murphy's sign

B. McBurney’s point tenderness

, C. Grey Turner’s sign

D. Cullen's sign


Correct Answer: B

Rationale: McBurney’s point tenderness (1/3 distance from anterior superior iliac spine to

umbilicus) is classic for appendicitis.




✅ Question 006

Which drug class is first-line for treating generalized anxiety disorder (GAD)?


A. Benzodiazepines

B. SSRIs

C. SNRIs

D. Beta-blockers


Correct Answer: B

Rationale: SSRIs are first-line for GAD due to efficacy and safety in long-term use.

Benzodiazepines are not first-line due to dependence risk.




✅ Question 007

What is the primary function of the loop of Henle in the nephron?
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2 weeks ago

2 weeks ago

Thank you very much

6 months ago

Excellent 3P test bank! Clear rationales, updated questions, and great coverage of patho, pharm, and assessment. Helped me pass!

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