NBME CBSE ACTUAL TEST QUESTIONS AND ANSWERS 2024/2025(Quiz bank with all the correct answers)(usmle step 1)Medical examination

s TEST QUESTIONS AND ANSWERS 2024/2025(Quiz bank with all the correct answers)(usmle step
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s 1)Medical examination s




NBME CBSE ACTUAL
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Decreased Osteoclast Activity s s



62 year old woman - osteoporosis – a
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s bisphosphonate is prescribed. The s s s



expected beneficial effect of the drug is s s s s s s



s due to which of the following?
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Cohot Study of elderly women – relative
s s s s s s Statistically Significant Overall Increase Risk
s s s s



s risk ratio for hip fractures among those
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who exercise regularly is 1.2 (95%
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confidence interval of 1.1 to 1.8). Which of
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the following is the conclusion about the
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effect of exercise on the risk of hip
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fracture?

52 year old man goes to ER with chest pain
s s s s s s s s s Increased nitric oxide concentration
s s s



s radiating to his jaw while shoveling snow. s s s s s s



Pulse is 80/min and blood pressure is
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130/70. The most immediate treatments s s s



mechanism of action?
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24 year old woman – spilled hot grease on
s s s s s s s s a. Vascular Endothelial Growth Factor
s s s s



her left leg while working at a fast-food
s s s s s s s s VEGF – stimulates angiogenesiss.
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s restaurant. Exam of leg shows 7cm pink, s s s s s s TYPE III Collagen = Blood Vessels – early wound
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s soft, granular, edematous wound. The
s s s s repair
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formation of this tissue was most likely s s s s s s



caused by increased activity of which?
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27 year old man- MVC – skull x-ray shows a
s s s s s s s s s a. Adenylyl Cyclase
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linear, nondepressed basal skull fracture –
s s s s s s Adenylate Cyclase – ATP – CAMP --
s s s s s s



increased serum osm and decreased urin
s s s s s s PROTEKINASE A -- Ca s s s



osm. Following desmopressin urine osm
s s s s s v2
increases. Desmopressin’s effect is due to s s s s s



the activation of which of the following?
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A 10 month old boy – 4 day history of fever
s s s s s s s s s s Mediation of Cell Entry via a fusion protein
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and cough. He attends day care center.
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Chest exam shows intercostal retractions
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s along with bilateral, diffuse wheezes and
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expiratory rhonchi. The infectious agent
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s most likely has which of the following
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properties?




https://quizlet.com/547918595/nbme-new-tests-flash-cards/ 1/12

, A 17 year old girl in ED – 15 minutes after
s s s s s s s s s s B2- Agonist
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being stung by a bee. Mild light
s s s s s s s



s headedness but no difficulty swallowing- s s s s



Bilateral wheezing - Which is most s s s s s



appropriate pharmacotherapy for this s s s



patient?
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14 year old boy - 2 day history of sore throat
s s s s s s s s s s Infectious Mononucleosis
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and feverthat peaks in late
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afternoon. 1 week of fatigue. He recentaly s s s s s s



s had sex with one partner. Physical exam
s s s s s s



s show cervical lymphadenopathy and
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pharyngeal erythema with a creamy s s s s



s exudate. DX? s




57 year old man – radiation therapy for
s s s s s s s G1
s squamous cell carcinoma of the lung. s s s s s



s Despite therapy, tumor increases in size s s s s s



and he dies 6 months later.The
s s s s s s s



progressive tumor growth is due to a s s s s s s



s defect in cell cycle arrest in which of the
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following phases of cell cycle?
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28 year old – lived in sub-Saharan Africa –
s s s s s s s s Schistosomiasis
until he came to the US. Temp of 100.4 –
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imaging shows bilateral hydroureter and s s s s



s hydronephrosis. Biopsy shows marked s s s



fibrosis and scattered granulomas. DX?
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A couple with a family history of a-
s s s s s s s 50%
s thalassemia. Woman has one gene s s s s



deletion and man has two gene deletion. If s s s s s s s



s the two gene is trans – what percentage of
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s offspring will have a two gene deletion? s s s s s s




previously healthy 40 year brought to s s s s s Thrombotic Thrombocytopenia Purpura
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emergency department by her husband – 2 s s s s s s



s day history of fever, lethargy, confusion. PE
s s s s s s



shows scattered petechiae and
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ecchymoses over the lower extremities – s s s s s



s 3+ polychromasia and 3+ schistocytes and
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Low platelets Dx?
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16 year old boy – is admitted to the ER
s s s s s s s s s Hemopneumpothorax under tension
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s because of a knife wound to the left side of s s s s s s s s s



s his chest.AnX-ray of the chest shows an
s s s s s s s s



air-fluid level in the left side of the chest, s s s s s s s s



s partial collapse of the left lung, and the
s s s s s s s



elevation of the stomach bubble. The
s s s s s s



mediastinum is midline. DX? s s s




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