NR546 week 3 test your knowledge quiz
While _________ is a defining characteristic of some psychotic disorders, ANS-psychosis may
also have a psychotic component. Two dones and a rone, or ANS, bind more strongly to the
5HT 2A receptor than to the D2 receptor or equally to both receptors. - less sedative and less
likely to make you gain weight, but they are more likely to cause hyperprolactinemia and EPS. 2
pips and a rip—ANS-pips—have a lower risk of metabolic side effects and weight gain, bind to
D2 receptors more effectively than 5HT-2A, and they may cause EPS. -rips has a low risk of
metabolic disorders and binds to both D2 and 5HT-2A receptors in equal amounts. The
Abnormal Involuntary Movement Scale (AIMS) - ANS is a tool used to monitor tardive
dyskinesia and involuntary movements in antipsychotic patients. -it is recommended and best
practice to document the AIMS at least once every six months for patients taking antipsychotic
or dopamine blockers. Adding 5HT2A antagonists: - ANS- Enhance D2 blockade's antipsychotic
efficacy and reduce its side effects - ANS--cardiac concerns: QT prolongation, torsades de
pointes, and sudden cardiac death are additional adverse effects of excessive D2 receptor
blockade (D2 antagonist actions). -blood dyscrasias (neutropenia, leukopenia, and
agranulocytosis)
-aspiration and dysmotility of the esophagus -a higher chance of falling akathisia, also known
as ANS, is an inner restlessness that leads to repetitive motions like rocking and tapping
fingers. Alex is a returning client who reports leaking fluid from his nipples. The most likely
cause of these undesirable side effects is which of the following: ANS-Risperidone due to
hyperprolactinemia, galactorrhea is the most likely condition. The neurotransmitter systems
ANS-dopamine, serotonin, and glutamate are connected to all forms of psychosis. Logia is a
form of ANS communication breakdown. - speech insecurity anhedonia - ANS-a diminished
ability to experience pleasure
ANS, or antipsychotics, are mostly used to treat schizophrenia and other psychotic disorders.
-also used as adjunctive medications to treat depression and other conditions that resist
antidepressants. -not curative
-reduce symptoms and improve quality of life Prescriptions for antipsychotics are based on
their: - ANS--pharmacological properties -profiles of side effects -adverse effects based on the
particular symptoms and requirements of each individual throughout their lifetime D2 receptor
blocker-caused abnormal motor symptoms are collectively referred to as ANS-extrapyramidal
symptsom (EPS). -motor effects caused by D2 antagonists area of the brain thought to be
responsible for the positive symptoms of schizophrenia is the ____________. one of the
neuronal pathways known to be affected here is the ___________ from the _____________
and the _____________. - ANS-limbic system, mesolimbic pathway, ventral tegmental area
(VTA), nucleus accumbens
aripiprazole (Abilify) - ANS-Indication: FDA approved for schizophrenia ages 13 and older
Risk:
Low metabolic risk
Low risk for weight gain
, Orthostatic hypotension is rare. asenapine (Saphris) - ANS-Indication: FDA approved for
schizophrenia ages 10 and older
Special Notes: Available as a transdermal and sublingual patch Risk:
Low risk to the metabolism lack of interest in social interactions is known as asociality (ANS).
avolition - ANS--lack of motivation
-reduced ability to complete everyday tasks
The ANS-based Barnes Akathisia Rating Scale (BARS) bradykinesia - ANS-Slowness of
movement
brexpiprazole (Rexulti) - ANS-Indication: FDA approved for schizophrenia
Special Notes: Known for its cognitive benefits Risk:
Low risk to the metabolism cariprazine (Vraylar) - ANS-Indication: schizophrenia treatment that
has been approved by the FDA Risk:
Low metabolic risk
Carla is a 35-year-old woman that is currently taking olanzapine for her diagnosed
schizophrenia. In the past six months, she has put on 30 pounds and now has a waist
circumference of 37 inches. She requests a change in medications. Which of the following
drugs has a lower risk of weight gain? ANS-aripiprazole and quetiapine -associated with the
lowest risk weight gain.
caused by persistent inhibition of D2 receptors in the nigrostriatal dopamine pathway - ANS-TD
-tx: interventions that lower dopamine neurotransmission, inhibiting the vesicular monoamine
transporter type 2 (VMAT2) lowers the "go" signals - deuterated tetrabenazine
(deutetrabenazine), Valbenazine (most selective and potent) ,
Clients are more likely to experience side effects when changing from a medication in one
___________ to a medication in another ____________ - ANS-subcategory, subcategory
(for instance, pine to finished) clozapine (Clozaril) - ANS-Indication: Approved for
treatment-resistant schizophrenia and chronic suicidal behavior in schizophrenia or
schizoaffective disorder
Not recommended in cases of acute schizophrenia presentation. Special Notes: When used,
the Absolute Neutrophil Count (ANC) must be greater than 1500/mm3, and WBC, granulocyte,
and neutrophil counts must be monitored initially and weekly. Risk:
High metabolic risk
most likely to gain weight. Low EPS risk.
Warning from the black box: may result in severe neutropenia Contraindicated in liver disease
and hepatic failure
not the first choice for schizophrenia treatment Commonly prescribed antipsychotic medications
for treatment of positive schizophrenic symptoms - ANS-lowest to highest potency
-chlorpromazine (low)
-mesoridazine (low)
-thioridazine (low)
-thiothixene (a medicine) -fluphenazine (a medicine) -haloperidol (high)
Diagnoses Requiring Psychosis -- ANS -- Schizophrenia -Substance-induced psychotic
disorders
-A disorder with schizophrenia - Disorder with schizophrenia -Delusional disorder
-Brief psychotic disorder
While _________ is a defining characteristic of some psychotic disorders, ANS-psychosis may
also have a psychotic component. Two dones and a rone, or ANS, bind more strongly to the
5HT 2A receptor than to the D2 receptor or equally to both receptors. - less sedative and less
likely to make you gain weight, but they are more likely to cause hyperprolactinemia and EPS. 2
pips and a rip—ANS-pips—have a lower risk of metabolic side effects and weight gain, bind to
D2 receptors more effectively than 5HT-2A, and they may cause EPS. -rips has a low risk of
metabolic disorders and binds to both D2 and 5HT-2A receptors in equal amounts. The
Abnormal Involuntary Movement Scale (AIMS) - ANS is a tool used to monitor tardive
dyskinesia and involuntary movements in antipsychotic patients. -it is recommended and best
practice to document the AIMS at least once every six months for patients taking antipsychotic
or dopamine blockers. Adding 5HT2A antagonists: - ANS- Enhance D2 blockade's antipsychotic
efficacy and reduce its side effects - ANS--cardiac concerns: QT prolongation, torsades de
pointes, and sudden cardiac death are additional adverse effects of excessive D2 receptor
blockade (D2 antagonist actions). -blood dyscrasias (neutropenia, leukopenia, and
agranulocytosis)
-aspiration and dysmotility of the esophagus -a higher chance of falling akathisia, also known
as ANS, is an inner restlessness that leads to repetitive motions like rocking and tapping
fingers. Alex is a returning client who reports leaking fluid from his nipples. The most likely
cause of these undesirable side effects is which of the following: ANS-Risperidone due to
hyperprolactinemia, galactorrhea is the most likely condition. The neurotransmitter systems
ANS-dopamine, serotonin, and glutamate are connected to all forms of psychosis. Logia is a
form of ANS communication breakdown. - speech insecurity anhedonia - ANS-a diminished
ability to experience pleasure
ANS, or antipsychotics, are mostly used to treat schizophrenia and other psychotic disorders.
-also used as adjunctive medications to treat depression and other conditions that resist
antidepressants. -not curative
-reduce symptoms and improve quality of life Prescriptions for antipsychotics are based on
their: - ANS--pharmacological properties -profiles of side effects -adverse effects based on the
particular symptoms and requirements of each individual throughout their lifetime D2 receptor
blocker-caused abnormal motor symptoms are collectively referred to as ANS-extrapyramidal
symptsom (EPS). -motor effects caused by D2 antagonists area of the brain thought to be
responsible for the positive symptoms of schizophrenia is the ____________. one of the
neuronal pathways known to be affected here is the ___________ from the _____________
and the _____________. - ANS-limbic system, mesolimbic pathway, ventral tegmental area
(VTA), nucleus accumbens
aripiprazole (Abilify) - ANS-Indication: FDA approved for schizophrenia ages 13 and older
Risk:
Low metabolic risk
Low risk for weight gain
, Orthostatic hypotension is rare. asenapine (Saphris) - ANS-Indication: FDA approved for
schizophrenia ages 10 and older
Special Notes: Available as a transdermal and sublingual patch Risk:
Low risk to the metabolism lack of interest in social interactions is known as asociality (ANS).
avolition - ANS--lack of motivation
-reduced ability to complete everyday tasks
The ANS-based Barnes Akathisia Rating Scale (BARS) bradykinesia - ANS-Slowness of
movement
brexpiprazole (Rexulti) - ANS-Indication: FDA approved for schizophrenia
Special Notes: Known for its cognitive benefits Risk:
Low risk to the metabolism cariprazine (Vraylar) - ANS-Indication: schizophrenia treatment that
has been approved by the FDA Risk:
Low metabolic risk
Carla is a 35-year-old woman that is currently taking olanzapine for her diagnosed
schizophrenia. In the past six months, she has put on 30 pounds and now has a waist
circumference of 37 inches. She requests a change in medications. Which of the following
drugs has a lower risk of weight gain? ANS-aripiprazole and quetiapine -associated with the
lowest risk weight gain.
caused by persistent inhibition of D2 receptors in the nigrostriatal dopamine pathway - ANS-TD
-tx: interventions that lower dopamine neurotransmission, inhibiting the vesicular monoamine
transporter type 2 (VMAT2) lowers the "go" signals - deuterated tetrabenazine
(deutetrabenazine), Valbenazine (most selective and potent) ,
Clients are more likely to experience side effects when changing from a medication in one
___________ to a medication in another ____________ - ANS-subcategory, subcategory
(for instance, pine to finished) clozapine (Clozaril) - ANS-Indication: Approved for
treatment-resistant schizophrenia and chronic suicidal behavior in schizophrenia or
schizoaffective disorder
Not recommended in cases of acute schizophrenia presentation. Special Notes: When used,
the Absolute Neutrophil Count (ANC) must be greater than 1500/mm3, and WBC, granulocyte,
and neutrophil counts must be monitored initially and weekly. Risk:
High metabolic risk
most likely to gain weight. Low EPS risk.
Warning from the black box: may result in severe neutropenia Contraindicated in liver disease
and hepatic failure
not the first choice for schizophrenia treatment Commonly prescribed antipsychotic medications
for treatment of positive schizophrenic symptoms - ANS-lowest to highest potency
-chlorpromazine (low)
-mesoridazine (low)
-thioridazine (low)
-thiothixene (a medicine) -fluphenazine (a medicine) -haloperidol (high)
Diagnoses Requiring Psychosis -- ANS -- Schizophrenia -Substance-induced psychotic
disorders
-A disorder with schizophrenia - Disorder with schizophrenia -Delusional disorder
-Brief psychotic disorder
