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Exam (elaborations)

NR507 Midterm Edapt Review (Weeks 1–3) – Chamberlain University – 2024/2025 – Questions with 100% Accurate Answers

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This document provides a complete review of Edapt questions and 100% accurate answers from Weeks 1 to 3 of the NR507 Advanced Pathophysiology course at Chamberlain University. Covered topics include cellular injury and adaptation, immune and inflammatory responses, and early endocrine system foundations. It’s the perfect resource for midterm exam preparation and mastering foundational pathophysiology concepts.

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2024/2025
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NR507 MIDTERM EDAPT REVIEW (WEEKS 1-3)
QUESTIONS WITH 100% ACCURATE ANSWERS
Choose the interstitial lung diseases that are the most diagnosed:

Lupus
Radiation pneumonitis
Pneumoconioses
Acute interstitial pneumonia
Hypersensitivity Pneumonitis
Desquamative interstitial pneumonia - Accurate answers Radiation pneumonitis
Pneumoconioses
Hypersensitivity Pneumonitis

Hives (urticaria) are an example of a: - Accurate answers Type 1 hypersensitivity reaction.

Anaphylaxis is a
___________
hypersensitivity reaction. - Accurate answers type 1

Allergic contact dermatitis is an example of
________________
hypersensitivity reaction. - Accurate answers type 4

Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: - Accurate answers IgG or IgM.

Which of the following are considered the "first responders" of the innate immune system? - Accurate
answers Neutrophils.

Type I (Mechanism, Example, Pathology) - Accurate answers IgE action on mast cells Hay fever
Mast cell degranulation results in an inflammatory response

Type II (Mechanism, Example, Pathology) - Accurate answers Tissue-specific destruction or
impairment because of:
Antibody binding followed by lysis via complement
Antibody binding followed by macrophage phagocytosis
Antibody binding followed by neutrophil destruction
Antibody-dependent cell (NK)-mediated cytotoxicity, or
Antireceptor antibodies
1-ABO incompatibility
5-Graves' disease
1-Complement damages RBC membrane and cells lyse
5-Autoantibodies specific for thyroid tissue impair receptor for TSH

,Type III (Mechanism, Example, Pathology) - Accurate answers Antigen-Antibody complex deposited
in tissues Raynaud's phenomenon Complex deposited in small peripheral vessels in cool temperatures
leading to vasoconstriction and blocked circulation

Type IV (Mechanism, Example, Pathology) - Accurate answers Cytotoxic T cell-mediated Contact
dermatitis (e.g., poison ivy) T cells attack tissue directly (no antibody)

Damage occurs with ABO incompatibility because: - Accurate answers Complement damages RBC
membrane causing cell lysis.

Which of the following is the underlying pathology for hay fever? - Accurate answers Mast cell
degranulation.

The diagnosis for an individual who presents to the office with sudden swollen lips and eyes, shortness
of breath and throat tightness after a bee sting is: - Accurate answers Anaphylaxis.

Which of the following assessment findings would be expected in a patient who presents with urticaria?
- Accurate answers Eosinophilia.

An example of a secondary immunodeficiency is: - Accurate answers Pneumocystis Carinii.

__________ is a predominant cause of secondary immune deficiencies worldwide. - Accurate answers
Malnutrition

An example of a primary immunodeficiency is: - Accurate answers Chronic Granulomatous Disease.

Which of the following is an autoimmune disease? - Accurate answers Systemic Lupus
Erythematosus (SLE).

Examples: Primary Immunodeficiencies - Accurate answers Chronic granulomatous Disease of
Childhood, DiGeorge Syndrome, Familial Mediterranean fever, Job Syndrome,
Common Variable Immunodeficiency

Examples: Secondary Immunodeficiencies - Accurate answers Human Immunodeficiency Virus,
Pneumocystis Carinii, Pneumonia, Sinus infection, Lung cancer

T/F primary immunodeficiency:
Are less common and occur due to a defect on the development of the immune system. - Accurate
answers true

T/F primary immunodeficiency Conditions where the immune system becomes compromised because of
something else. - Accurate answers false

T/F Sinusitis is considered a primary immunodeficiency. - Accurate answers false

A patient with human immunodeficiency virus (HIV) was admitted to the acute care facility with
difficulty breathing. He is diagnosed with Pneumocytis carinii. Pneumocystis carinii an example of: -
Accurate answers secondary immune disease

, t/f Cancer is a secondary immunodeficiency. - Accurate answers true

Which of the following findings can be used to diagnose Systemic Lupus Erythematosus (SLE)? -
Accurate answers Facial rash confined to the cheeks.

A renal disease most often associated with autoimmunity is: - Accurate answers
Glomerulonephritis.

The major immune system change associated with Sjogren's Syndrome is: - Accurate answers
Autoantibodies and auto-reactive T-cells against apoptotic cells.

Which of the following can depress a person's normal immune function? Exercise, psychological stress,
HTN, high fiber diet - Accurate answers psych stress

t/f The presenting signs and symptoms of an autoimmune disease is similar across all autoimmune
diseases. - Accurate answers false

Which of the following assessment findings would support a diagnosis of Rheumatoid Arthritis (RA)?
-Swollen metacarpophalangeal joints.
-A butterfly rash across the facial cheeks.
-Inflammation in the salivary and lacrimal glands.
-Muscle weakness and ataxia. - Accurate answers Swollen metacarpophalangeal joints.

t/f The presence of a low number of autoantibodies is an indicator that the individual will develop an
autoimmune disease. - Accurate answers false

t/f The following immune components can be involved in autoimmune diseases: T-Cells, B-cells and
autoantibodies. - Accurate answers true

Which of the following indices measures the average size of red blood cells?
-Mean Corpuscular Volume (MCV).
-Mean Corpuscular Hemoglobin Concentration (MCHC).
-Hemoglobin (Hb).
-Reticulocyte count. - Accurate answers Mean Corpuscular Volume (MCV).

Anemia can be caused from which of the following? (Select all that apply.)
-Excessive blood loss.
-Increased red blood cell destruction.
-Impaired red blood cell production. - Accurate answers all the above

Which of the following is characterized as a microcytic, hypochromic anemia?
Hereditary spherocytosis
Iron deficiency
Folate deficiency
B12 deficiency - Accurate answers iron deficiency

Which of the following normocytic anemias is characterized by hyperchromic RBCs?

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