CHAPTER 1-52 |COMPLETE GUIDE NEWEST VERSION 2023
,Contents
chapter 1- Concepts of Health and Disease ......................................................................... 3
chapter 2- Cell and Tissue Characteristics ......................................................................... 16
chapter 3- Cellular Adaptation, Injury, and Death ............................................................. 29
chapter 4- Genetic Control of Cell Function and Inheritance.............................................. 41
chapter 5- Genetic and Congenital Disorders .................................................................... 53
chapter 6- Neoplasia ........................................................................................................ 66
chapter 7- Stress and Adaptation ..................................................................................... 78
chapter 8- Disorders of Fluid and Electrolyte, and Acid Base Balance ................................ 91
chapter 9- Inflammation, Tissue Repair, and Wound Healing .......................................... 116
chapter 10- Mechanisms of Infectious Disease................................................................ 140
chapter 11- Innate and Adaptive Immunity .................................................................... 152
chapter 12- Disorders of the Immune Response .............................................................. 165
chapter 13- Organization and Control of Neural Function ............................................... 191
chapter 14- Somatosensory Function, Pain, and Temperature ........................................ 205
chapter 15- Disorders of Motor Function ........................................................................ 219
chapter 16- Disorders of Brain Function .......................................................................... 231
chapter 17-Sleep and sleep disturbances ........................................................................ 245
chapter 18- Disorders of Thought, Emotion, and Memory ............................................... 258
chapter 19- Disorders of Visual Function ........................................................................ 271
chapter 20- Disorders of Hearing and Vestibular Function............................................... 284
chapter 21- Blood Cells and the Hematopoietic System .................................................. 297
chapter 22- Disorders of Hemostasis .............................................................................. 309
chapter 23- Disorders of Red Blood Cells ........................................................................ 322
chapter 24- Disorders of White Blood Cells and Lymphoid Tissues .................................. 335
chapter 25- Structure and Function of the Cardiovascular System ................................... 348
chapter 26- Disorders of Blood Flow ............................................................................... 361
chapter 27- Disorders of Cardiac Function ...................................................................... 386
chapter 28 Disorders of Cardiac Conduction and Rhythm ................................................ 414
chapter 29- Structure and Function of the Respiratory System ........................................ 429
, chapter 30- Respiratory Tract Infections and Neoplasms................................................. 453
chapter 31- Disorders of Ventilation and Gas Exchange .................................................. 465
chapter 32- Structure and Function of the Kidney ........................................................... 478
chapter 33- Disorders of Renal Function ......................................................................... 490
chapter 34- Acute Kidney Injury and Chronic Kidney Disease .......................................... 504
chapter 35- Disorders of the Bladder and Lower Urinary Tract ........................................ 516
chapter 36- Structure and Function of the Gastrointestinal System ................................. 530
chapter 37- Disorders of Gastrointestinal Function ......................................................... 543
chapter 38- Disorders of Hepatobiliary and Pancreas Function........................................ 558
chapter 39- Alterations in Nutritional Status................................................................... 572
chapter 40- Mechanisms of Endocrine Control ................................................................ 585
chapter 41-Disorders of Endocrine Control ..................................................................... 597
chapter 42- Structure and Function of the Male Reproductive System ............................ 611
chapter 43- Disorders of the Male Reproductive System ................................................. 623
chapter 44- Structure and Function of the Female Reproductive System ......................... 637
chapter 45- Disorders of the Female Reproductive System ............................................. 650
chapter 46- Sexually Transmitted Infections ................................................................... 663
chapter 47- Structure and Function of the Musculoskeletal System ................................ 676
chapter 48- Disorders of Musculoskeletal Function: Trauma, Infection, Neoplasms ......... 687
chapter 49- Disorders of Musculoskeletal Function: Developmental and ......................... 701
chapter 50- Disorders of Musculoskeletal Function: Rheumatic Disorders ....................... 713
chapter 51- Structure and Function of the Skin ............................................................... 727
chapter 52- Disorders of Skin Integrity and Function ....................................................... 739
chapter 1- Concepts of Health and Disease
1. At an international nursing conference, many
,discussions and breakout sessions focused on the
World Health Organization (WHO) views on health.
Of the following comments made by nurses during a
discussion session, which statements would be
considered a good representation of the WHO
definition? Select all that apply.
A) Interests in keeping the elderly population
engaged in such activities as book reviews and
word games during social time
B)
Increase in the number of chair aerobics classes
provided in the skilled care facilities
C)
Interventions geared toward keeping the elderly
population diagnosed with diabetes mellitus
under tight blood glucose control by providing
in-home cookingclasses
D)
Providing transportation for renal dialysis patients to and from their haemodialysis Sessions
E) Providing handwashing teaching sessions to a group of young children
ANS:A, B, C, E
Feedback:
The WHO definition of health is defined as “a state of complete physical, mental, and
social well-being and not merely the absence of disease and infirmity.” Engaging in
book reviews facilitates mental and social well-being; chair aerobics helps facilitate
physical well-being; and assisting with tight control of diabetes helps with facilitating
physical well-being even though the person has a chronic disease. Handwashing is vital
,in the prevention of disease and spread of germs.
2. A community health nurse is teaching a group of recent graduates about the large
variety of factors that influence an individual's health or lack thereof. The nurse is
referring to the Healthy People 2020 report from the U.S. Department of Health and
Human Services as a teaching example. Of the following aspects discussed, which
would be considered a determinant of health that is outside the focus of this report?
A) The client has a diverse background by being of Asian and Native American
descent and practices various alternative therapies to minimize effects of stress.
B) The client has a family history of cardiovascular disease related to
hypercholesterolemia and remains noncompliant with the treatment regime.
C) The client has a good career with exceptional preventative health care benefits.
D) The client lives in an affluent, clean, suburban community with access to many
health care facilities.
ANS:B
Feedback:
In Healthy People 2020, the focus is to promote good health to all (such as using
alternative therapies to minimize effects of stress); achieving health equity and
promoting health for all (which includes having good health care benefits); and
promoting good health (which includes living in a clean community with good access to
health care). A client's noncompliance with treatments to control high cholesterol levels
within the presence of a family history of CV disease does not meet the “attaining lives
free of preventable disease and premature death” determinant.
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3. A physician is providing care for a number of patients on a medical unit of a large,
university hospital. The physician is discussing with a colleague the differentiation
,between diseases that are caused by abnormal molecules and diseases that cause disease.
Which of the following patients most clearly demonstrates the consequences of
molecules that cause disease?
A) A 31-year-old woman with sickle cell anemia who is receiving a transfusion of
packed red blood cells
B) A 91-year-old woman who has experienced an ischemic stroke resulting from
familial hypercholesterolemia
C) A 19-year-old man with exacerbation of his cystic fibrosis requiring oxygen
therapy and chest physiotherapy
D) A 30-year-old homeless man who has Pneumocystis carinii pneumonia (PCP) and
is HIV positive.
ANS:D
Feedback:
PCP is an example of the effect of a molecule that directly contributes to disease. Sickle
cell anemia, familial hypercholesterolemia, and cystic fibrosis are all examples of the
effects of abnormal molecules.
4. A member of the health care team is researching the etiology and pathogenesis of a
number of clients who are under his care in a hospital context. Which of the following
aspects of clients' situations bNesUt characterizes pathogeneses rather than etiology?
A) A client who has been exposed to the Mycobacterium tuberculosis bacterium
B) A client who has increasing serum ammonia levels due to liver cirrhosis
C) A client who was admitted with the effects of methyl alcohol poisoning
D) A client with multiple skeletal injuries secondary to a motor vehicle accident
ANS:B
Feedback:
Pathogenesis refers to the progressive and evolutionary course of disease, such as the
increasing ammonia levels that accompany liver disease. Bacteria, poisons, and
traumatic injuries are examples of etiologic factors.
,5. A new myocardial infarction patient requiring angioplasty and stent placement has
arrived to his first cardiac rehabilitation appointment. In this first session, a review of
the pathogenesis of coronary artery disease is addressed. Which statement by the patient
verifies to the nurse that he has understood the nurse's teachings about coronary artery
disease?
A) “All I have to do is stop smoking, and then I won't have any more heart attacks.”
B) “My artery was clogged by fat, so I will need to stop eating fatty foods like
French fries every day.”
C) “Sounds like this began because of inflammation inside my artery that made it
easy to form fatty streaks, which lead to my clogged artery.”
D) “If I do not exercise regularly to get my heart rate up, blood pools in the veins
causing a clot that stops blood flow to the muscle, and I will have a heart attack.”
ANS:C
Feedback:
The true etiology/cause of coronary artery disease (CAD) is unknown; however, the
pathogenesis of the disorder relates to the progression of the inflammatory process from
a fatty streak to the occlusive vessel lesion seen in people with coronary artery disease.
Risk factors for CAD revolve around cigarette smoking, diet high in fat, and lack of
exercise.
6. A 77-year-old man is a hospital inpatient admitted for exacerbation of his chronic
obstructive pulmonary disease (COPD), and a respiratory therapist (RT) is assessing the
client for the first time. WhicNh ofRtheIfolGloTwBin.gCaOspMects of the patient's current state of
health would be best characterized as a symptom rather than a sign?
A) The patient's oxygen saturation is 83% by pulse oxymetry.
B) The patient notes that he has increased work of breathing when lying supine.
C) The RT hears diminished breath sounds to the patient's lower lung fields
bilaterally.
D) The patient's respiratory rate is 31 breaths/minute.
ANS:B
, Feedback:
Symptoms are subjective complaints by the person experiencing the health problem,
such as complaints of breathing difficulty. Oxygen levels, listening to breath sounds,
and respiratory rate are all objective, observable signs of disease.
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7. Which of the following situations would be classified as a complication of a disease or
outcome from the treatment regimen? Select all that apply.
A) Massive pulmonary emboli following diagnosis of new-onset atrial fibrillation
B) Burning, intense incision pain following surgery to remove a portion of colon due
to intestinal ganglionitis
C) Development of pulmonary fibrosis following treatment with bleomycin, an
antibiotic chemotherapy agent used in treatment of lymphoma
D) Gradual deterioration in ability to walk unassisted for a patient diagnosed with
Parkinson disease
E) Loss of short-term memory in a patient diagnosed with Alzheimer disease
ANS:A, C
Feedback:
Development of pulmonary emboli and pulmonary fibrosis following chemotherapy are
both examples of a complication (adverse extensions of a disease or outcome from
treatment). It is normal to expect incisional pain following surgery. As Parkinson
disease progresses, the inability to walk independently is expected. This is a normal
progression for people diagnosed with Parkinson's. Loss of short-term memory in a
patient diagnosed with Alzheimer disease is an expected finding.
8. Laboratory testing is ordered for a male patient during a clinic visit for a routine
follow-up assessment of hypertension. When interpreting lab values, the nurse knows
that
A) a normal value represenNtsUtRheStIesNt reTsuBlts thOat fall within the bell curve.
B) if the lab result is above the 50% distribution, the result is considered elevated.