Genetics and Genomics in Nursing and Health Care
Theresa A. Beery, M. Linda Workman, and Julia A. Eggert
2nd Edition
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,Table70of70Contents
Chapter700170DNA70Structure70and70Function 1
Chapter700270Protein70Synthesis 9
Chapter700370Genetic70Influence70on70Cell70Division,70Differentiation,70and70Gametogenesis 19
Chapter700470Patterns70of70Inheritance 29
Chapter700570Epigenetic70Influences70on70Gene70Expression 43
Chapter700670Autosomal70Inheritance70and70Disorders 47
Chapter700770Sex70Chromosome70and70Mitochondrial70Inheritance70and70Disorders 55
Chapter700870Family70History70and70Pedigree70Construction 61
Chapter700970Congenital70Anomalies,70Basic70Dysmorphology,70and70Genetic70Assessment 68
Chapter701070Enzyme70and70Collagen70Disorders 74
Chapter701170Common70Childhood-Onset70Genetic70Disorders 84
Chapter701270Common70Adult-Onset70Disorders 95
Chapter701370Cardiovascular70Disorders 103
Chapter701470The70Genetics70of70Cancer 110
Chapter701570Genetic70Contributions70to70Psychiatric70and70Behavioral70Disorders 119
Chapter701670Genetic70and70Genomic70Testing 124
Chapter701770Assessing70Genomic70Variation70in70Drug70Response 129
Chapter701870Health70Professionals70and70Genomic70Care 135
Chapter701970Financial,70Ethical,70Legal,70and70Social70Considerations 140
Chapter702070Genetic70and70Genomic70Variation 144
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70Genetics70and70Genomics70in70Nursing70and70Health70Care,702nd70Edition70(Beery,7
Chapter701:70DNA70Structure70and70Function
02019)
MULTIPLE70CHOICE
1. In70which70body70or70cell70area70are70most70genes70in70humans70located?
a. Nucleus
b. Mitochondrion
c. Cytoplasm
d. Plasma70membrane
ANS:7 0 7 0 A
Most70genes70are70part70of70the70DNA70located70in70the70nucleus70of70body70cells.70Only70a70f
ew70genes70are70located70in70a70cell’s70mitochondrion70or70mitochondria.70There70are70no70gen
es70or70DNA70in70either70the70cytoplasm70or70the70plasma70membranes70of70any70cell.
2. Which70condition70or70statement70exemplifies70the70concept70of70genomics70rather70than70geneti
cs?
a. The70gene70for70insulin70is70located70on70chromosome701170in70all70people.
b. Expression70of70any70single70gene70is70dependent70on70inheriting70two70alleles.
c. Sex-linked70recessive70disorders70affect70males70more70often70than70females.
d. One70allele70for70each70gene70is70inherited70from70the70mother,70and70one70is70inher
ited70from70the70father.
ANS:7 0 7 0 A
Genetics70is70the70study70of70the70general70mechanisms70of70heredity70and70the70variation70
of70inherited70traits.70Genomics70is70the70study70of70the70function70of70all70the70nucleotide70
sequences70present70within70the70entire70genome70of70a70s p e c i e s , Wi nWcW
l u.d iTn B
g 70S
geMn.
esWiS
n70D
NA70coding70regions70and70DNA70noncoding
regions.70Selections70B,70C,70and70D70all70refer70to70mechanisms70of70heredity.70Only70selection
70A70refers
to70the70function70of70a70specific70nucleotide70sequence.
3. What70is70the70purpose70of70phosphorous70in70a70DNA70strand?
a. Linking70the70nucleotides70into70a70strand
b. Holding70complementary70strands70together
c. Ensuring70that70a70purine70is70always70paired70with70a70pyrimidine
d. Preventing70the70separation70of70double-stranded70DNA70into70single-stranded70DNA
ANS:7 0 7 0 A
Each70nucleoside70becomes70a70complete70nucleotide70when70a70phosphate70group70is70attac
hed.70The70phosphates70have70multiple70binding70sites,70and70each70one70can70link70to70two
70nucleotides.70These70linkages70allow70the70nucleotides70to70be70connected70when70placed
70into70the70DNA70strand.70The70nucleotides70within70each70strand70are70held70in70position70
by70the70linked70phosphate70groups,70which70act70like70the70string70holding70a70strand70of70
beads70together,70forming70a70necklace.
4. What70is70the70term70used70to70define70alternative70forms70of70a70gene70that70may70res
ult70in70different70expression70of70the70trait70coded70for70by70that70gene?
a. Alleles
b. Bases
c. Centromeres
d. Diploids
70ANS:7 0
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AGenetics70and70Genomics70in70Nursing70and70Health70Care,702nd70Edition70(Beery,7
70
02019)
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