2nd Edition
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Genetics79and79Genomics79in79Nursing79and79Health79Care
,Table79of79Contents
Chapter790179DNA79Structure79and79Function 1
Chapter790279Protein79Synthesis 9
Chapter790379Genetic79Influence79on79Cell79Division,79Differentiation,79and79Gametogenesis 19
Chapter790479Patterns79of79Inheritance 29
Chapter790579Epigenetic79Influences79on79Gene79Expression 43
Chapter790679Autosomal79Inheritance79and79Disorders 47
Chapter790779Sex79Chromosome79and79Mitochondrial79Inheritance79and79Disorders 55
Chapter790879Family79History79and79Pedigree79Construction 61
Chapter790979Congenital79Anomalies,79Basic79Dysmorphology,79and79Genetic79Assessment 68
Chapter791079Enzyme79and79Collagen79Disorders 74
Chapter791179Common79Childhood-Onset79Genetic79Disorders 84
Chapter791279Common79Adult-Onset79Disorders 95
Chapter791379Cardiovascular79Disorders 103
Chapter791479The79Genetics79of79Cancer 110
Chapter791579Genetic79Contributions79to79Psychiatric79and79Behavioral79Disorders 119
Chapter791679Genetic79and79Genomic79Testing 124
Chapter791779Assessing79Genomic79Variation79in79Drug79Response 129
Chapter791879Health79Professionals79and79Genomic79Care 135
Chapter791979Financial,79Ethical,79Legal,79and79Social79Considerations 140
Chapter792079Genetic79and79Genomic79Variation 144
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76Genetics76and76Genomics76in76Nursing76and76Health76Care,762nd76Edition76(Beery,7
Chapter791:79DNA79Structure79and79Function
62019)
MULTIPLE79CHOICE
1. In79which79body79or79cell79area79are79most79genes79in79humans79located?
a. Nucleus
b. Mitochondrion
c. Cytoplasm
d. Plasma79membrane
ANS:7 9 7 9 A
Most79genes79are79part79of79the79DNA79located79in79the79nucleus79of79body79cells.79Only79a79f
ew79genes79are79located79in79a79cell’s79mitochondrion79or79mitochondria.79There79are79no79gen
es79or79DNA79in79either79the79cytoplasm79or79the79plasma79membranes79of79any79cell.
2. Which79condition79or79statement79exemplifies79the79concept79of79genomics79rather79than79geneti
cs?
a. The79gene79for79insulin79is79located79on79chromosome791179in79all79people.
b. Expression79of79any79single79gene79is79dependent79on79inheriting79two79alleles.
c. Sex-linked79recessive79disorders79affect79males79more79often79than79females.
d. One79allele79for79each79gene79is79inherited79from79the79mother,79and79one79is79inher
ited79from79the79father.
ANS:7 9 7 9 A
Genetics79is79the79study79of79the79general79mechanisms79of79heredity79and79the79variation79
of79inherited79traits.79Genomics79is79the79study79of79the79function79of79all79the79nucleotide79
sequences79present79within79the79entire79genome79of79a79s p e c i e s , Wi nWcW
l u.d iTn B
g 79S
geMn.
esWiS
n79D
NA79coding79regions79and79DNA79noncoding
regions.79Selections79B,79C,79and79D79all79refer79to79mechanisms79of79heredity.79Only79selection
79A79refers
to79the79function79of79a79specific79nucleotide79sequence.
3. What79is79the79purpose79of79phosphorous79in79a79DNA79strand?
a. Linking79the79nucleotides79into79a79strand
b. Holding79complementary79strands79together
c. Ensuring79that79a79purine79is79always79paired79with79a79pyrimidine
d. Preventing79the79separation79of79double-stranded79DNA79into79single-stranded79DNA
ANS:7 9 7 9 A
Each79nucleoside79becomes79a79complete79nucleotide79when79a79phosphate79group79is79attac
hed.79The79phosphates79have79multiple79binding79sites,79and79each79one79can79link79to79two
79nucleotides.79These79linkages79allow79the79nucleotides79to79be79connected79when79placed
79into79the79DNA79strand.79The79nucleotides79within79each79strand79are79held79in79position79
by79the79linked79phosphate79groups,79which79act79like79the79string79holding79a79strand79of79
beads79together,79forming79a79necklace.
4. What79is79the79term79used79to79define79alternative79forms79of79a79gene79that79may79res
ult79in79different79expression79of79the79trait79coded79for79by79that79gene?
a. Alleles
b. Bases
c. Centromeres
d. Diploids
79ANS:7 6
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AGenetics76and76Genomics76in76Nursing76and76Health76Care,762nd76Edition76(Beery,7
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62019)
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