Overview of NUBEQA for Prostate
Cancer Treatment questions with
answers
What is NUBEQA® and what is its primary use? ✅✅NUBEQA (darolutamide) is a
prescription medicine used to treat adults with prostate cancer that has not spread (non-
metastatic castration-resistant prostate cancer or nmCRPC) or that has spread
(metastatic hormone-sensitive prostate cancer or mHSPC), in combination with
docetaxel.
How does NUBEQA® affect overall survival in nmCRPC? ✅✅NUBEQA extended
overall survival by lowering the risk of death in nmCRPC by 31% when added to
hormone therapy compared to hormone therapy alone.
What is the impact of NUBEQA® on survival in mHSPC? ✅✅NUBEQA extended
overall survival by lowering the risk of death in mHSPC by 32% when added to hormone
therapy and docetaxel compared to hormone therapy and chemotherapy alone.
How much longer did men with nmCRPC live without prostate cancer spreading when
taking NUBEQA®? ✅✅Men with nmCRPC who took NUBEQA and hormone therapy
lived more than twice as long without prostate cancer spreading, with a median of 3.4
years compared to 1.5 years for those on hormone therapy alone.
What does hormone therapy include in the context of NUBEQA®? ✅✅Hormone
therapy includes drug treatments or surgery that lowers testosterone.
What are the important safety considerations before taking NUBEQA®? ✅✅Before
taking NUBEQA, inform your healthcare provider about any medical conditions,
including heart problems, high blood pressure, diabetes, dyslipidemia, history of
seizures, brain injury, stroke, kidney or liver problems, and pregnancy.
What is the significance of the term 'median' in the context of NUBEQA® results?
✅✅Median refers to the middle value in a set of numbers, used to describe survival
times in clinical studies.
What type of prostate cancer does NUBEQA® treat? ✅✅NUBEQA treats non-
metastatic castration-resistant prostate cancer (nmCRPC) and metastatic hormone-
sensitive prostate cancer (mHSPC).
What is the role of docetaxel in the treatment with NUBEQA®? ✅✅Docetaxel is used
in combination with NUBEQA for treating metastatic hormone-sensitive prostate cancer
(mHSPC).
, What is the primary location of prostate cancer? ✅✅Prostate cancer occurs in the
prostate, a small gland located below the bladder.
What does it mean for prostate cancer to be metastatic? ✅✅Metastatic prostate
cancer means it has spread to other parts of the body, such as bones, lungs, liver, or
lymph nodes.
What are the pages to refer to for results in mHSPC and nmCRPC? ✅✅Results in
mHSPC can be found on pages 8-9, and results in nmCRPC can be found on pages 10-
11.
What are the side effects associated with NUBEQA®? ✅✅Side effects for NUBEQA
in mHSPC and nmCRPC are discussed in the brochure, specifically in sections
dedicated to side effects.
What is the importance of understanding your diagnosis in prostate cancer?
✅✅Knowing your diagnosis helps you discuss treatment options with your healthcare
provider.
What should you do if you are pregnant or planning to become pregnant before taking
NUBEQA®? ✅✅You should inform your healthcare provider, as NUBEQA can cause
harm to an unborn baby and may lead to miscarriage.
What is the dosage form of NUBEQA®? ✅✅NUBEQA is available in 300 mg tablets.
What is the clinical study in nmCRPC designed to measure? ✅✅The clinical study in
nmCRPC was designed to measure metastasis-free survival (MFS) and overall survival.
What is the significance of the orange color in the brochure? ✅✅Information about
metastatic hormone-sensitive prostate cancer (mHSPC) is colored orange in the
brochure.
What are some medical conditions to disclose before taking NUBEQA®?
✅✅Conditions include heart problems, high blood pressure, diabetes, dyslipidemia,
history of seizures, brain injury, stroke, kidney or liver problems.
Is NUBEQA® known to be safe and effective for women or children? ✅✅It is not
known if NUBEQA is safe and effective in women or children.
What is the primary purpose of the NUBEQA® brochure? ✅✅The brochure provides
information about NUBEQA, its uses, results, side effects, and important safety
information.
Cancer Treatment questions with
answers
What is NUBEQA® and what is its primary use? ✅✅NUBEQA (darolutamide) is a
prescription medicine used to treat adults with prostate cancer that has not spread (non-
metastatic castration-resistant prostate cancer or nmCRPC) or that has spread
(metastatic hormone-sensitive prostate cancer or mHSPC), in combination with
docetaxel.
How does NUBEQA® affect overall survival in nmCRPC? ✅✅NUBEQA extended
overall survival by lowering the risk of death in nmCRPC by 31% when added to
hormone therapy compared to hormone therapy alone.
What is the impact of NUBEQA® on survival in mHSPC? ✅✅NUBEQA extended
overall survival by lowering the risk of death in mHSPC by 32% when added to hormone
therapy and docetaxel compared to hormone therapy and chemotherapy alone.
How much longer did men with nmCRPC live without prostate cancer spreading when
taking NUBEQA®? ✅✅Men with nmCRPC who took NUBEQA and hormone therapy
lived more than twice as long without prostate cancer spreading, with a median of 3.4
years compared to 1.5 years for those on hormone therapy alone.
What does hormone therapy include in the context of NUBEQA®? ✅✅Hormone
therapy includes drug treatments or surgery that lowers testosterone.
What are the important safety considerations before taking NUBEQA®? ✅✅Before
taking NUBEQA, inform your healthcare provider about any medical conditions,
including heart problems, high blood pressure, diabetes, dyslipidemia, history of
seizures, brain injury, stroke, kidney or liver problems, and pregnancy.
What is the significance of the term 'median' in the context of NUBEQA® results?
✅✅Median refers to the middle value in a set of numbers, used to describe survival
times in clinical studies.
What type of prostate cancer does NUBEQA® treat? ✅✅NUBEQA treats non-
metastatic castration-resistant prostate cancer (nmCRPC) and metastatic hormone-
sensitive prostate cancer (mHSPC).
What is the role of docetaxel in the treatment with NUBEQA®? ✅✅Docetaxel is used
in combination with NUBEQA for treating metastatic hormone-sensitive prostate cancer
(mHSPC).
, What is the primary location of prostate cancer? ✅✅Prostate cancer occurs in the
prostate, a small gland located below the bladder.
What does it mean for prostate cancer to be metastatic? ✅✅Metastatic prostate
cancer means it has spread to other parts of the body, such as bones, lungs, liver, or
lymph nodes.
What are the pages to refer to for results in mHSPC and nmCRPC? ✅✅Results in
mHSPC can be found on pages 8-9, and results in nmCRPC can be found on pages 10-
11.
What are the side effects associated with NUBEQA®? ✅✅Side effects for NUBEQA
in mHSPC and nmCRPC are discussed in the brochure, specifically in sections
dedicated to side effects.
What is the importance of understanding your diagnosis in prostate cancer?
✅✅Knowing your diagnosis helps you discuss treatment options with your healthcare
provider.
What should you do if you are pregnant or planning to become pregnant before taking
NUBEQA®? ✅✅You should inform your healthcare provider, as NUBEQA can cause
harm to an unborn baby and may lead to miscarriage.
What is the dosage form of NUBEQA®? ✅✅NUBEQA is available in 300 mg tablets.
What is the clinical study in nmCRPC designed to measure? ✅✅The clinical study in
nmCRPC was designed to measure metastasis-free survival (MFS) and overall survival.
What is the significance of the orange color in the brochure? ✅✅Information about
metastatic hormone-sensitive prostate cancer (mHSPC) is colored orange in the
brochure.
What are some medical conditions to disclose before taking NUBEQA®?
✅✅Conditions include heart problems, high blood pressure, diabetes, dyslipidemia,
history of seizures, brain injury, stroke, kidney or liver problems.
Is NUBEQA® known to be safe and effective for women or children? ✅✅It is not
known if NUBEQA is safe and effective in women or children.
What is the primary purpose of the NUBEQA® brochure? ✅✅The brochure provides
information about NUBEQA, its uses, results, side effects, and important safety
information.
