Rationales for Nursing Practice, 12th Edition
(Frandsen, 2021), Chapters 1 - 61
,
,
, Chapter 1, The Foundation of Pharmacology: Quality and Safety
1. A woman diagnosed with obsessive–compulsive disorder has been
prescribed oral paroxetine hydrochloride. What is the expected effect for
this prescription?
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
ANSWER: B
Rationale: Drugs that produce systemic effects are taken into the body, circulated
through the bloodstream to their sites of action in various body tissues, and
eventually eliminated from the body. Curative agents are given to cure a disease
process. In this case, paroxetine hydrochloride will control the symptoms but not
cure the disorder. Drugs with local effects, such as sunscreen and local anesthetics,
act mainly at the site of application. Paroxetine hydrochloride is not administered
parenterally. Parenteral agents are administered subcutaneously, intramuscularly,
or intravenously.
PTS: 1 REF: p. 3, Introduction OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
substance that has been cheGmRicA
alDlyEm
SoBdOifOieSd.TWhaOt M
.C is another name for this
type of medication?
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototype drug
ANSWER: B
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring
substances that have been chemically modified. Synthetic drugs are more
standardized in their chemical characteristics, more consistent in their effects, and
less likely to produce allergic reactions. Biotechnology drugs involve manipulating
DNA and RNA and recombining genes into hybrid molecules that can be inserted
into living organisms. Prototype drugs are the first drug of a particular group to be
developed.
PTS: 1 REF: p. 3, Drug Sources OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and