BCACP – Clinical Examtest Questions And
Answers
Which atypical antiPs are approved for maintenance of BPD (vs only acute) - ANSWER-
olanz
quetiapine
Both also ok for acute
Mood stabilizers to avoid in preg - ANSWER- Li
VPA
CBZ
Top - face defect
olanz - increased wt and preeclampsia
Which antiPs are preg B? - ANSWER- clozapine
lurasidone
Which antiPs have greatest risk of hyperprolactinemia - ANSWER- typical APs
risperidone
paliperiodne
which antiPs increase QTc the worst? - ANSWER- thioridazine (BBW)
Pimozide
Haldol (IV)
quetiapine
which drugs have BBW of increased risk of death in dementia - ANSWER- antiPs
which atypical antiPs have high sedation - ANSWER- clozaril
quetiapine
zypeza
which atypical antiPs have highest risk of EPS - ANSWER- cariprazine (Vraylar)
latuda
,important counseling point for Latuda admin - ANSWER- take w/ 350 cal for increased
abs
important counseling point for paliperidone - ANSWER- ghost tab in stool
what ANC is needed to start Clozapine? when should you stop? - ANSWER- 1500 to
start
stop at 1000, but can restart when >1000
stop forever at 500
tx for akathesia (restless/agitation) - ANSWER- low dose propranolol + ativan
or
mirtaz
avoid ACh
tx for TD - ANSWER- stop/change AP
valbenazine (Ingrezza) 40/d x 1 w, then 80/d
avoid ACh
which AP has no metabolic SEs - ANSWER- latuda
which APs have worst wt gain - ANSWER- risp
olanz
cloz
quetiapin
e
BBWs for clozapine - ANSWER- neutropenia
sz (dose-dep)
myocarditis
orthohypoTN
dosing for LA inj, po overlap?
Haldol
Fluphenazine
Risperdal
Paliperidone (Invega)
Zyprexa
, Abilify - ANSWER- Haldol q4w (no PO if load)
Fluphenazine q2w (no PO)
Risperdal q3w (3 w PO overlap, need to fridge & reconstitute)
Paliperidone q4w (sustenna) or q3mo (trinza) (no PO if load)
Zyprexa q2-4w (no PO, but sometimes used)
Abilify q1mo (14 d overlap)
which inj antiP has REMS for post-dose delerium/sedation --> 1st dose in clinic w/ 3 hrs
obs - ANSWER- zyprexa
atomoxetine
- dose
- onset
- GI
- BBW
- use in combo w/ stimulants? - ANSWER- <70 kg: 0.5 m/k/d (1.2 m/k/d)
>70 kg: 40 mg/d (100 mg/d)
onset = 4 weeks
SE = GI <- take w/ food
BBW = SI
more SEs if used with stimulants
buproprion (zyban) for smoking - ANSWER- 150mg/d x 3 days, then 150 BID
varenacline (chantix) for smoking - ANSWER- 0.5/d x 3
0.5 BID x 3 d
1 BID (quit date)
lower dose if CrCl<30
start 8-35 d < quit date
only FDA app med for opioid WD in preg - ANSWER- methadone
buprenorphine for opioid WD
- max dose
- when to start - ANSWER- max 60mg/d
start when mild WD sx start
gonorrhea tx - ANSWER- CTX 250 IM + Azithro 1 g PO x 1
Answers
Which atypical antiPs are approved for maintenance of BPD (vs only acute) - ANSWER-
olanz
quetiapine
Both also ok for acute
Mood stabilizers to avoid in preg - ANSWER- Li
VPA
CBZ
Top - face defect
olanz - increased wt and preeclampsia
Which antiPs are preg B? - ANSWER- clozapine
lurasidone
Which antiPs have greatest risk of hyperprolactinemia - ANSWER- typical APs
risperidone
paliperiodne
which antiPs increase QTc the worst? - ANSWER- thioridazine (BBW)
Pimozide
Haldol (IV)
quetiapine
which drugs have BBW of increased risk of death in dementia - ANSWER- antiPs
which atypical antiPs have high sedation - ANSWER- clozaril
quetiapine
zypeza
which atypical antiPs have highest risk of EPS - ANSWER- cariprazine (Vraylar)
latuda
,important counseling point for Latuda admin - ANSWER- take w/ 350 cal for increased
abs
important counseling point for paliperidone - ANSWER- ghost tab in stool
what ANC is needed to start Clozapine? when should you stop? - ANSWER- 1500 to
start
stop at 1000, but can restart when >1000
stop forever at 500
tx for akathesia (restless/agitation) - ANSWER- low dose propranolol + ativan
or
mirtaz
avoid ACh
tx for TD - ANSWER- stop/change AP
valbenazine (Ingrezza) 40/d x 1 w, then 80/d
avoid ACh
which AP has no metabolic SEs - ANSWER- latuda
which APs have worst wt gain - ANSWER- risp
olanz
cloz
quetiapin
e
BBWs for clozapine - ANSWER- neutropenia
sz (dose-dep)
myocarditis
orthohypoTN
dosing for LA inj, po overlap?
Haldol
Fluphenazine
Risperdal
Paliperidone (Invega)
Zyprexa
, Abilify - ANSWER- Haldol q4w (no PO if load)
Fluphenazine q2w (no PO)
Risperdal q3w (3 w PO overlap, need to fridge & reconstitute)
Paliperidone q4w (sustenna) or q3mo (trinza) (no PO if load)
Zyprexa q2-4w (no PO, but sometimes used)
Abilify q1mo (14 d overlap)
which inj antiP has REMS for post-dose delerium/sedation --> 1st dose in clinic w/ 3 hrs
obs - ANSWER- zyprexa
atomoxetine
- dose
- onset
- GI
- BBW
- use in combo w/ stimulants? - ANSWER- <70 kg: 0.5 m/k/d (1.2 m/k/d)
>70 kg: 40 mg/d (100 mg/d)
onset = 4 weeks
SE = GI <- take w/ food
BBW = SI
more SEs if used with stimulants
buproprion (zyban) for smoking - ANSWER- 150mg/d x 3 days, then 150 BID
varenacline (chantix) for smoking - ANSWER- 0.5/d x 3
0.5 BID x 3 d
1 BID (quit date)
lower dose if CrCl<30
start 8-35 d < quit date
only FDA app med for opioid WD in preg - ANSWER- methadone
buprenorphine for opioid WD
- max dose
- when to start - ANSWER- max 60mg/d
start when mild WD sx start
gonorrhea tx - ANSWER- CTX 250 IM + Azithro 1 g PO x 1
