MSCI 660 Principles of Cellular Biology Quiz: Intracellular
Membrane Traffic and Cellular Sorting Score quiz 125 out
of 125 Liberty University Online Academy
Instructions
The quiz:
• Covers the Learn material from Module 5: Week 5 – Module 6: Week 6.
• Contains 50 multiple-choice questions.
• Is limited to 75 minutes.
• Allows 1 attempt.
• Is worth 125 points.
Submit this assignment by 11:59 p.m. (ET) on Sunday of Module 6: Week 6.
Attempt History
Attempt Time Score
LATEST Attempt 1 59 minutes 125 out of 125
Correct answers are hidden.
Score for this quiz: 125 out of 125
Question 1
2..5 pts
Which of the following is a major consequence of activation of phospholipase C-β (PLCβ) by the
Gq
trimeric GTPase?
Elevation of intracellular cAMP levels, leading to the activation of protein kinase A
Elevation of PIP 3
levels in the plasma membrane, leading to the activation of protein kinase B
Elevation of intracellular Ca
2+
levels, leading to the activation of protein kinase C
Elevation of IP in the plasma membrane, leading to the activation of protein kinase D
3
Elevation of intracellular cGMP levels, leading to the activation of protein kinase G
Question 2
2..5 pts
,Consider the signaling pathway depicted below, which involves two different receptors. Assume
that a protein is active only when it is activated but not inhibited by its upstream signaling
molecules. Activation and inhibition are indicated by normal and blunt arrows, respectively.
Under which of the following conditions is target-gene expression induced?
Only in the presence of both signals (1 and 2)
In the presence of either or both signals (1 or
2)
In the presence of either signal but not both of them
Only in the absence of both signals
Only in the presence of signal 2 but not signal 1
, Question 3
2..5 pts
Indicate true (T) and false (F) statements below regarding receptor-mediated endocytosis of
LDL particles. Your answer would be a four-letter string composed of letters T and F only, e.g.
TTTF. ( ) LDL receptors are normally degraded in the lysosome along with their LDL ligands.
( ) LDL receptors that do not bind to extracellular LDL cannot be internalized in clathrin-coated
vesicles.
( ) A mutation that impairs the attachment of an LDL receptor to a clathrin-coated pit
would cause depletion of blood LDL levels.
( ) LDL receptors at the plasma membrane are usually concentrated in clathrin-coated pits.
TTTF
FTFT
FTTT
TFFT
FFFT
Question 4
2..5 pts
In the following simplified diagram, the activation of a hypothetical allosteric protein is plotted
as a function of effector molecule concentration. Which curve (A to E) do you think
corresponds to a condition in which activation requires the highest number of effector
molecules bound to each protein?
Membrane Traffic and Cellular Sorting Score quiz 125 out
of 125 Liberty University Online Academy
Instructions
The quiz:
• Covers the Learn material from Module 5: Week 5 – Module 6: Week 6.
• Contains 50 multiple-choice questions.
• Is limited to 75 minutes.
• Allows 1 attempt.
• Is worth 125 points.
Submit this assignment by 11:59 p.m. (ET) on Sunday of Module 6: Week 6.
Attempt History
Attempt Time Score
LATEST Attempt 1 59 minutes 125 out of 125
Correct answers are hidden.
Score for this quiz: 125 out of 125
Question 1
2..5 pts
Which of the following is a major consequence of activation of phospholipase C-β (PLCβ) by the
Gq
trimeric GTPase?
Elevation of intracellular cAMP levels, leading to the activation of protein kinase A
Elevation of PIP 3
levels in the plasma membrane, leading to the activation of protein kinase B
Elevation of intracellular Ca
2+
levels, leading to the activation of protein kinase C
Elevation of IP in the plasma membrane, leading to the activation of protein kinase D
3
Elevation of intracellular cGMP levels, leading to the activation of protein kinase G
Question 2
2..5 pts
,Consider the signaling pathway depicted below, which involves two different receptors. Assume
that a protein is active only when it is activated but not inhibited by its upstream signaling
molecules. Activation and inhibition are indicated by normal and blunt arrows, respectively.
Under which of the following conditions is target-gene expression induced?
Only in the presence of both signals (1 and 2)
In the presence of either or both signals (1 or
2)
In the presence of either signal but not both of them
Only in the absence of both signals
Only in the presence of signal 2 but not signal 1
, Question 3
2..5 pts
Indicate true (T) and false (F) statements below regarding receptor-mediated endocytosis of
LDL particles. Your answer would be a four-letter string composed of letters T and F only, e.g.
TTTF. ( ) LDL receptors are normally degraded in the lysosome along with their LDL ligands.
( ) LDL receptors that do not bind to extracellular LDL cannot be internalized in clathrin-coated
vesicles.
( ) A mutation that impairs the attachment of an LDL receptor to a clathrin-coated pit
would cause depletion of blood LDL levels.
( ) LDL receptors at the plasma membrane are usually concentrated in clathrin-coated pits.
TTTF
FTFT
FTTT
TFFT
FFFT
Question 4
2..5 pts
In the following simplified diagram, the activation of a hypothetical allosteric protein is plotted
as a function of effector molecule concentration. Which curve (A to E) do you think
corresponds to a condition in which activation requires the highest number of effector
molecules bound to each protein?
