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ANCC Family Nurse Practitioner Board Exam Study Guide – Comprehensive Clinical Review (USA, 2025) – Key Medical Concepts and Treatments

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This detailed study guide compiles essential concepts for the ANCC FNP board exam, covering over 90 clinical topics including chronic conditions, pharmacologic treatments, infectious diseases, pediatrics, geriatrics, dermatology, cardiology, endocrinology, and diagnostic criteria. It emphasizes evidence-based guidelines, high-yield facts, and includes key treatments and differentials crucial for advanced practice nurses. The content is ideal for final review and clinical decision-making refinement before exam day.

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ANCC FNP Board Exam Study Guide

Key Concepts in Common Medical
Conditions and Treatments
1. Chronic Bronchitis
 Definition: A type of Chronic Obstructive Pulmonary Disease (COPD)
characterized by inflammation of the bronchi, leading to excess mucus
production.
 Key Characteristics:
o Diagnosis typically after age 35.
o Often associated with obesity.
o Production of copious amounts of purulent sputum.
o Possible elevated Hematocrit (Hct) level.
 Treatment:
o Short-Acting Beta Agonists (SABA): Example: Albuterol.
o Inhaled Anticholinergics: Example: Ipratropium.
 Normal Lung Auscultation Findings:
o Lower Lobes: Vesicular breath sounds (soft and low).
o Upper Lobes: Bronchial breath sounds (louder).


2. Actinic Keratosis
 Patient Profile: Typically affects older to elderly fair-skinned adults.
 Lesion Characteristics: Numerous dry, round, pink to red-colored, slow-
growing lesions that do not heal.
 Common Locations: Sun-exposed areas such as cheeks, nose, face, arms,
and back.
 Significance: Precancerous precursor of squamous cell carcinoma.
 Risk Factor: History of frequent sunburns as a child increases risk.
 Diagnosis: Confirmed with biopsy.
 Treatment:
o Cryotherapy: For a small number of lesions.
o 5-FU (5% Fluorouracil) Cream: For a large number of lesions.
 Follow-up: Essential with a dermatologist.

,3. Seborrheic Keratosis
 Lesion Characteristics: Soft, round, wart-like fleshy growths
predominantly on the trunk (mostly on the back).
 Appearance: Can range in color from light tan to black and appear to be
"pasted on".
 Symptoms: Generally asymptomatic.
 Nature: Benign.

4. Fingernail Hematoma Treatment
 Procedure: Trephination - creating a hole in the nail (through drilling or
piercing) to allow blood to drain.

5. Hypothyroidism
 Primary Hypothyroidism:
o Elevated TSH (Thyroid-Stimulating Hormone).
o Low T4 (Thyroxine).
o Low or normal T3 (Triiodothyronine).
 Subclinical Hypothyroidism:
o Elevated TSH.
o Normal T4.
o Normal T3.
 Common Cause: Hashimoto's thyroiditis (autoimmune).
 Symptoms: Variable, may include fatigue.
 Treatment: Levothyroxine (Synthroid) daily in the AM on an empty
stomach.
 Starting Dose: Typically 25-50 mcg.
 Monitoring: Check TSH every 6-8 weeks to assess treatment effectiveness.

6. Hyperthyroidism
 Primary Hyperthyroidism:
o Low TSH.
o High T4.
o Normal or high T3.
 Subclinical Hyperthyroidism:
o Low TSH.

, o Normal T4.
o Normal T3.
 Most Common Cause: Grave's Disease (autoimmune).
 Common Symptoms: More prevalent in females, rapid weight loss,
increased heart rate, tremors, sweating, irritability, anxiety,
hyperactivity, insomnia, diarrhea, amenorrhea, hypertension,
exophthalmos (protruding eyeballs), heat intolerance, goiter (enlarged
thyroid gland).
 Treatment:
o Propylthiouracil (PTU).
o Methimazole (Tapazole).
o Radioactive Iodine: Often leads to lifelong hypothyroidism and is
contraindicated in pregnancy.
 Thyroid Storm (Thyrotoxicosis):
o Acute worsening of symptoms.
o May be triggered by stress or infection.
o Look for altered level of consciousness (LOC), fever, abdominal
pain.
o Life-threatening condition requiring immediate hospitalization.


7. Increased Risk of Ectopic Pregnancy
 Risk Factors: Previous ectopic pregnancy, salpingitis (inflammation of
the fallopian tubes), tubal surgery, current Intrauterine Device (IUD)
use, previous cervicitis, history of Pelvic Inflammatory Disease (PID).
 Symptoms: Abdominal pain (worsens when supine or with jarring),
vaginal bleeding, amenorrhea, low-grade fever, pain referred to the
right shoulder (may indicate rupture).

8. Hypertension Medications Part 1
 African-American Patients (with or without diabetes): Initial treatment
options include thiazide diuretic or Calcium Channel Blocker (CCB).
 Non-Black Patients (with or without diabetes): Initial treatment options
include thiazide diuretic, CCB, ACE inhibitor, or Angiotensin Receptor
Blocker (ARB).
 Thiazide Diuretics ("-ide"):
o Excellent synergist when used with other antihypertensives.
o Avoid in sulfa allergy.

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