BIO 361 ETC & ATP SYNTHASE EXAM
QUESTIONS WITH 100%RATED ANSWERS
2024/2025 LATEST UPDATED/GET A+
(True/False) Complex I provides a pathway for the metabolic use of lactate for production of
glucose - False. Complex one is the oxidation of NADH by CoQ.
(True/False) The inner mitochondrial membrane divides the mitochondrion into the inner
membrane space and the outer membrane space - False.
The Cori cycle is effective because - it allows the use of the lactate generated during anaerobic
glycolysis to produce pyruvate. Lactate is transported out of muscle cells into liver cells, where
is can be used to make glucose.
Which of the following statements is true regarding the movement of protons as electrons are
passed through redox centers of the ETC embedded in the inner mitochondrial membrane? -
Protons are pumped into the intermembrane space from the matrix.
Which of the following is TRUE regarding the complexes within the electron transport system? -
- Inhibition of Complex II would decrease the total number of electrons moving through the
electron transport chain.
- Inhibition of Complex II would not alter the amount of free energy generated from electrons
originating from NADH.
A description of the Cori cycle should include: - Lactate released into the blood from skeletal
muscles can act as a substrate for gluconeogenesis in the liver, but under conditions of enhanced
muscle activity the glucose synthesized in the liver is not used for glycogen synthesis but rather
for export back to the muscles for their use.
(True/False) Complexes I and II each transfer electrons to Coenzyme Q - True. Both complexes
transfer electrons to CoQ, but not in series.
Which of the prosthetic groups listed can accept or donate either one or two electrons due to the
stability of the semiquinone state? - Coenzyme Q, can be reduced by two elections sequentially
due to the stabile one electron semiquinone intermediate.
A poison that prevents the transfer of electrons from the last [Fe-S] cluster of Complex I to
coenzyme Q is added to a suspension of actively respiring mitochondria. Which of the following
will be observed? - ATP production would be reduced due to a decrease in the number of protons
pumped out of the mitochondrial matrix. ATP production can still occur through entry of other
complexes of the ETC.
Rotenone and amytal - I. inhibition can be restored by addition of succinate
QUESTIONS WITH 100%RATED ANSWERS
2024/2025 LATEST UPDATED/GET A+
(True/False) Complex I provides a pathway for the metabolic use of lactate for production of
glucose - False. Complex one is the oxidation of NADH by CoQ.
(True/False) The inner mitochondrial membrane divides the mitochondrion into the inner
membrane space and the outer membrane space - False.
The Cori cycle is effective because - it allows the use of the lactate generated during anaerobic
glycolysis to produce pyruvate. Lactate is transported out of muscle cells into liver cells, where
is can be used to make glucose.
Which of the following statements is true regarding the movement of protons as electrons are
passed through redox centers of the ETC embedded in the inner mitochondrial membrane? -
Protons are pumped into the intermembrane space from the matrix.
Which of the following is TRUE regarding the complexes within the electron transport system? -
- Inhibition of Complex II would decrease the total number of electrons moving through the
electron transport chain.
- Inhibition of Complex II would not alter the amount of free energy generated from electrons
originating from NADH.
A description of the Cori cycle should include: - Lactate released into the blood from skeletal
muscles can act as a substrate for gluconeogenesis in the liver, but under conditions of enhanced
muscle activity the glucose synthesized in the liver is not used for glycogen synthesis but rather
for export back to the muscles for their use.
(True/False) Complexes I and II each transfer electrons to Coenzyme Q - True. Both complexes
transfer electrons to CoQ, but not in series.
Which of the prosthetic groups listed can accept or donate either one or two electrons due to the
stability of the semiquinone state? - Coenzyme Q, can be reduced by two elections sequentially
due to the stabile one electron semiquinone intermediate.
A poison that prevents the transfer of electrons from the last [Fe-S] cluster of Complex I to
coenzyme Q is added to a suspension of actively respiring mitochondria. Which of the following
will be observed? - ATP production would be reduced due to a decrease in the number of protons
pumped out of the mitochondrial matrix. ATP production can still occur through entry of other
complexes of the ETC.
Rotenone and amytal - I. inhibition can be restored by addition of succinate
