LATEST UPDATE WGU D027 ADVANCED PAT n n n n n
HOPHARMACOLOGICAL FOUNDATIONS (AC n n
TUAL 2024-2025) QUESTIONS AND ANSWERS
n n n n
Why are aminosalicylates used for in patients with Crohn's di
n n n n n n n n n
sease? - ---answers n - Reduce inflammation
n n n
What are some aminosalicylates that are used to treat Crohn's di
n n n n n n n n n n
sease? - ---answers n - Sulfasalazine
n n
- Mesalamine
Why are corticosteroids used for in patients with Crohn's di
n n n n n n n n n
sease? - ---answers n n- Reduce inflammation n n
- Only used if aminosalicylates are not effective during an e
n n n n n n n n n
xacerbation
What are the sickle cell and parent traits? - ---answers
n n n n n n n n n -
Children who have, 25%
n n n n
- Children who do not have and are not carriers, 25%
n n n n n n n n n
- Children who are carriers, 50% n n n n
What is Huntington's disease? - ---answers
n n n n n -
Autosomal dominant disorder
n n n
- A person only needs one copy of each of the affected gene to de
n n n n n n n n n n n n n
velop the disorder
n n
- Each child has a 50% chance of inheriting the gene that ca
n n n n n n n n n n n
uses the disease
n n
, LATEST UPDATE WGU D027 ADVANCED PAT n n n n n
HOPHARMACOLOGICAL FOUNDATIONS (AC n n
TUAL 2024-2025) QUESTIONS AND ANSWERS
n n n n
- Leads to progressive degeneration of nerve cells that affects m
n n n n n n n n n
ovement, cognitive functions, and emotions
n n n n
What is an example of an autosommal dominant disorder? - --
n n n n n n n n n n
-answers - Huntington's disease n n
What is an example of an autosomal recessive disorder? - ---
n n n n n n n n n n
answers
n - Cystic fibrosis n n
What is cystic fibrosis? - ---answers
n n n n n -
Autosomal recessive disorder
n n n
- The lungs and the digestive system get clogged with mucus
n n n n n n n n n
- Affects the pancreas causing secretions in the lungs
n n n n n n n
- Caused by CTFR mutation n n n
What are some ways that cystic fibrosis affects the different pa
n n n n n n n n n n
rts in the body? - ---answers
n n n - n n
Lungs: block airways causing inflammation and increasing t
n n n n n n n n
he risk of infection, pulmonary hypertension, and tissue dama
n n n n n n n n
ge
- Digestive tract: block secretion of digestive enzymes from the
n n n n n n n n n
pancreases leading to malabsorption and malnutrition, can also l
n n n n n n n n
ead to chronic pancreatitis
n n n
, LATEST UPDATE WGU D027 ADVANCED PAT n n n n n
HOPHARMACOLOGICAL FOUNDATIONS (AC n n
TUAL 2024-2025) QUESTIONS AND ANSWERS n n n n
- Liver: blockage of the bile ducts can interfere with the liver's ab
n n n n n n n n n n n
ility to clear toxins from the blood leading to scarring, gallstones
n n n n n n n n n n
, and cirrhosis
n n
- Reproductive system: structural problems that renders the n n n n n n n
majority of men with this disorder to be infectable
n n n n n n n n
- Endocrine system: blockage of insulin- n n n n
producing cells on the pancreas (islets of Langerhans) can lea
n n n n n n n n n
d to type of diabetes that has characteristics of both type 1 and
n n n n n n n n n n n n
type 2 diabetes
n n n
What are some symptoms of patients with cystic fibrosis? - ---
n n n n n n n n n n
answers
n - Very salty-tasting skin n n n
- Postnasal drip, sinusitis n n
- Shortness of breath n n
- Repeated lung infections n n
- Foul-smelling, bulky greasy stools n n n
- Poor growth n
- Male infertility n
What are some diagnostic tests used to diagnose cystic fibrosis
n n n n n n n n n
? - ---answers
n n -
Sweat test (measures the amount of chloride in sweat)
n n n n n n n n n
, LATEST UPDATE WGU D027 ADVANCED PAT n n n n n
HOPHARMACOLOGICAL FOUNDATIONS (AC n n
TUAL 2024-2025) QUESTIONS AND ANSWERS
n n n n
- Genetic test (detects chromosomal mutations associated with t
n n n n n n n
he disease)
n
What is an example of x-linked dominant disorder? - ---
n n n n n n n n n
answers
n -
Duchenne muscular dystrophy inheritance (DMD)
n n n n n
- Color blindness n
What is Duchenne Muscular Dystrophy? ----- answers
n n n n - X-
n
linked dominant disorder
n n
- Until recently, children with this order did not live beyond th
n n n n n n n n n n
eir teens
n
- Life expectancy now 30's and some into their 40's to 50's
n n n n n n n n n n
- Affects the muscles, leading to muscle wasting that worsens o
n n n n n n n n n
ver time n
- Almost always affects boys and symptoms being early in c
n n n n n n n n n
hildhood
What are some signs and symptoms in patients with Duchenne
n n n n n n n n n n
Muscular Dystrophy? - ---answers -------------------- Difficulty
n n n
standing up, walking, and climbing stairs
n n n n n
- May have heart and lung problems
n n n n n
- Scoliosis
HOPHARMACOLOGICAL FOUNDATIONS (AC n n
TUAL 2024-2025) QUESTIONS AND ANSWERS
n n n n
Why are aminosalicylates used for in patients with Crohn's di
n n n n n n n n n
sease? - ---answers n - Reduce inflammation
n n n
What are some aminosalicylates that are used to treat Crohn's di
n n n n n n n n n n
sease? - ---answers n - Sulfasalazine
n n
- Mesalamine
Why are corticosteroids used for in patients with Crohn's di
n n n n n n n n n
sease? - ---answers n n- Reduce inflammation n n
- Only used if aminosalicylates are not effective during an e
n n n n n n n n n
xacerbation
What are the sickle cell and parent traits? - ---answers
n n n n n n n n n -
Children who have, 25%
n n n n
- Children who do not have and are not carriers, 25%
n n n n n n n n n
- Children who are carriers, 50% n n n n
What is Huntington's disease? - ---answers
n n n n n -
Autosomal dominant disorder
n n n
- A person only needs one copy of each of the affected gene to de
n n n n n n n n n n n n n
velop the disorder
n n
- Each child has a 50% chance of inheriting the gene that ca
n n n n n n n n n n n
uses the disease
n n
, LATEST UPDATE WGU D027 ADVANCED PAT n n n n n
HOPHARMACOLOGICAL FOUNDATIONS (AC n n
TUAL 2024-2025) QUESTIONS AND ANSWERS
n n n n
- Leads to progressive degeneration of nerve cells that affects m
n n n n n n n n n
ovement, cognitive functions, and emotions
n n n n
What is an example of an autosommal dominant disorder? - --
n n n n n n n n n n
-answers - Huntington's disease n n
What is an example of an autosomal recessive disorder? - ---
n n n n n n n n n n
answers
n - Cystic fibrosis n n
What is cystic fibrosis? - ---answers
n n n n n -
Autosomal recessive disorder
n n n
- The lungs and the digestive system get clogged with mucus
n n n n n n n n n
- Affects the pancreas causing secretions in the lungs
n n n n n n n
- Caused by CTFR mutation n n n
What are some ways that cystic fibrosis affects the different pa
n n n n n n n n n n
rts in the body? - ---answers
n n n - n n
Lungs: block airways causing inflammation and increasing t
n n n n n n n n
he risk of infection, pulmonary hypertension, and tissue dama
n n n n n n n n
ge
- Digestive tract: block secretion of digestive enzymes from the
n n n n n n n n n
pancreases leading to malabsorption and malnutrition, can also l
n n n n n n n n
ead to chronic pancreatitis
n n n
, LATEST UPDATE WGU D027 ADVANCED PAT n n n n n
HOPHARMACOLOGICAL FOUNDATIONS (AC n n
TUAL 2024-2025) QUESTIONS AND ANSWERS n n n n
- Liver: blockage of the bile ducts can interfere with the liver's ab
n n n n n n n n n n n
ility to clear toxins from the blood leading to scarring, gallstones
n n n n n n n n n n
, and cirrhosis
n n
- Reproductive system: structural problems that renders the n n n n n n n
majority of men with this disorder to be infectable
n n n n n n n n
- Endocrine system: blockage of insulin- n n n n
producing cells on the pancreas (islets of Langerhans) can lea
n n n n n n n n n
d to type of diabetes that has characteristics of both type 1 and
n n n n n n n n n n n n
type 2 diabetes
n n n
What are some symptoms of patients with cystic fibrosis? - ---
n n n n n n n n n n
answers
n - Very salty-tasting skin n n n
- Postnasal drip, sinusitis n n
- Shortness of breath n n
- Repeated lung infections n n
- Foul-smelling, bulky greasy stools n n n
- Poor growth n
- Male infertility n
What are some diagnostic tests used to diagnose cystic fibrosis
n n n n n n n n n
? - ---answers
n n -
Sweat test (measures the amount of chloride in sweat)
n n n n n n n n n
, LATEST UPDATE WGU D027 ADVANCED PAT n n n n n
HOPHARMACOLOGICAL FOUNDATIONS (AC n n
TUAL 2024-2025) QUESTIONS AND ANSWERS
n n n n
- Genetic test (detects chromosomal mutations associated with t
n n n n n n n
he disease)
n
What is an example of x-linked dominant disorder? - ---
n n n n n n n n n
answers
n -
Duchenne muscular dystrophy inheritance (DMD)
n n n n n
- Color blindness n
What is Duchenne Muscular Dystrophy? ----- answers
n n n n - X-
n
linked dominant disorder
n n
- Until recently, children with this order did not live beyond th
n n n n n n n n n n
eir teens
n
- Life expectancy now 30's and some into their 40's to 50's
n n n n n n n n n n
- Affects the muscles, leading to muscle wasting that worsens o
n n n n n n n n n
ver time n
- Almost always affects boys and symptoms being early in c
n n n n n n n n n
hildhood
What are some signs and symptoms in patients with Duchenne
n n n n n n n n n n
Muscular Dystrophy? - ---answers -------------------- Difficulty
n n n
standing up, walking, and climbing stairs
n n n n n
- May have heart and lung problems
n n n n n
- Scoliosis