Exam Questions with
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Question:
The first-pass effect occurs when hepatic metabolism decreases the
bioavailability of a drug. Oral forms of medications are processed
through the GI tract, absorbed through the small intestines, and
undergo the first-pass effect in the liver in which some of the active
ingredients are removed from the drug before it reaches the intended
site of action. Which route should the nurse clarify with the healthcare
provider prior to administering a drug with a high first-pass effect?
• Oral
• Buccal
• Sublingual
• Intravenous
, Correct Answer:
Oral
Question:
With the loss of exocrine function for a client with chronic pancreatitis,
replacement of pancreatic enzymes using pancrelipase (Pancrease)
becomes necessary. Diarrhea and steatorrhea (fatty stools) indicate
insufficient pancreatic enzymes are present to digest dietary fats and
other nutrients, so pancrelipase, a fat-digesting enzyme, should be
consumed with any type of food. Which instruction is most important
for the nurse to include in this client's teaching?
• Avoid prolonged exposure to direct sunlight
• Stay away from products containing alcohol
• Ingest 8 oz of grapefruit juice with the medication
• Take the medication when consuming food
Correct Answer:
Take the medication when consuming food
Question:
Beta-blockers are used to inhibit aqueous humor production, with the
goal of reducing intraocular pressure. What is the effect of beta-
blocking agents when used for treatment of glaucoma?
• Inhibiting aqueous humor production