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HESI pharm practice test 1 ACTUAL EXAM QUESTIONS AND CORRECT DETAILED ANSWERS (VERIFIED ANSWERS) ||ALREADY GRADED A+||NEWEST VERSION ( 2025/2026)

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Get exam-ready with this HESI Pharmacology Practice Test 1 — featuring real HESI-style questions, verified answers, and detailed rationales. Graded A+ and updated for 2025/2026, this PDF study guide helps nursing students master key drug classes, side effects, safe administration, and NCLEX-style questions. Ideal for RN or LPN students preparing for the HESI Pharm Specialty Exam or as a pharmacology refresher. Tags to Use hesi pharmacology practice test 1 hesi pharm questions and answers hesi pharm 2025 verified hesi rn pharmacology test hesi nursing pharm exam hesi pharm a+ graded pharmacology hesi review hesi test 1 pharm 2026 hesi drug questions nursing hesi pdf pharm test hesi pharm practice exam hesi specialty pharmacology HESI Pharmacology Practice Test 1 HESI Pharm Exam Questions 2025 HESI Pharm Verified Answers HESI Pharmacology Study Guide HESI RN Pharmacology Practice Exam HESI Pharm A+ Graded PDF HESI Pharmacology Rationales 2025 HESI Pharm Test Prep Pharmacology HESI RN Exam 2025/2026 HESI Pharm Nursing Test Latest HESI Pharmacology Questions HESI Practice Test 1 Pharm HESI Pharmacology NCLEX-Style Prep HESI pharm practice test 1 ACTUAL EXAM QUESTIONS AND CORRECT DETAILED ANSWERS (VERIFIED ANSWERS) ||ALREADY GRADED A+||NEWEST VERSION ( 2025/2026) Question: The first-pass effect occurs when hepatic metabolism decreases the bioavailability of a drug. Oral forms of medications are processed through the GI tract, absorbed through the small intestines, and undergo the first-pass effect in the liver in which some of the active ingredients are removed from the drug before it reaches the intended site of action. Which route should the nurse clarify with the healthcare provider prior to administering a drug with a high first-pass effect? • Oral • Buccal • Sublingual • Intravenous ️ Correct Answer: Oral ________________________________________ Question: With the loss of exocrine function for a client with chronic pancreatitis, replacement of pancreatic enzymes using pancrelipase (Pancrease) becomes necessary. Diarrhea and steatorrhea (fatty stools) indicate insufficient pancreatic enzymes are present to digest dietary fats and other nutrients, so pancrelipase, a fat-digesting enzyme, should be consumed with any type of food. Which instruction is most important for the nurse to include in this client's teaching? • Avoid prolonged exposure to direct sunlight • Stay away from products containing alcohol • Ingest 8 oz of grapefruit juice with the medication • Take the medication when consuming food ️ Correct Answer: Take the medication when consuming food ________________________________________ Question: Beta-blockers are used to inhibit aqueous humor production, with the goal of reducing intraocular pressure. What is the effect of beta-blocking agents when used for treatment of glaucoma? • Inhibiting aqueous humor production • Enhancing aqueous humor outflow • Increasing intraocular pressure • Preventing extraocular infection ️ Correct Answer: Inhibiting aqueous humor production ________________________________________ Question: The most frequent manifestations of chronic salicylate intoxication in adults are tinnitus and hearing loss. Which findings should the nurse identify in an adult client with possible chronic salicylate intoxication? • Tinnitus and hearing loss • Photosensitivity and nervousness • Acute gastrointestinal bleeding and anorexia • Hyperventilation and central nervous system effects ️ Correct Answer: Tinnitus and hearing loss ________________________________________ Question: Minocycline (Minocin), a tetracycline antibiotic, is used to treat mild cases of rheumatoid arthritis and can cause damage to the vestibular part of the inner ear, so the client should report dizziness or difficulty maintaining balance. A client with rheumatoid arthritis is receiving a prescription for minocycline (Minocin). Which side effect is most important for the nurse to instruct the client to report? • Loss of balance and dizziness • Nausea and vomiting • Headache and mouth sores • Abdominal pain and diarrhea ️ Correct Answer: Loss of balance and dizziness ________________________________________ Question: Recommended medical treatment for Helicobacter pylori includes the use of at least 2 different antibiotics and a proton pump inhibitor to decrease the incidence of antibiotic resistance. The nurse should expect the healthcare provider to prescribe what treatment regimen for a client with peptic ulcer caused by Helicobacter Pylori? (Select all that apply) • Clarithromycin (Biaxin) • Sulfisoxazole (Gantrisin) • Misoprostol (Cytotec) • Omeprazole (Prilosec) • Metronidazole (Flagyl) • Sucralfate (Carafate) ️ Correct Answer: • Clarithromycin (Biaxin) • Omeprazole (Prilosec) • Metronidazole (Flagyl) ________________________________________ Question: Allopurinol (Zyloprim) improves joint function in chronic gouty arthritis by reducing blood uric acid levels to prevent and promote regression of tophi. Low-dose colchicine, an anti-inflammatory agent specific for gout, is used concurrently with allopurinol, which can precipitate an incident of acute gouty arthritis. A client with chronic gouty arthritis takes allopurinol (Zyloprim) and experiences an acute attack of gouty arthritis. The healthcare provider prescribes concurrent low-dose colchicine. What information should the nurse provide the client that best explains the action of the colchicine? • Acts like aspirin to relieve pain. • Facilitates the excretion of uric acid. • Reduces inflammation at the affected site. • Prevents formation of uric acid crystals. ️ Correct Answer: Reduces inflammation at the affected site. ________________________________________ ________________________________________ Question: Lithium carbonate (Eskalith) causes hypothyroidism in 1 to 4% of those clients receiving the medication, so caregivers should assess for signs of hypothyroidism, including fatigue and constipation (early signs) and myxedema or goiter (late symptoms). A resident of a long-term care facility is taking lithium carbonate (Eskalith) to treat bipolar disorder. Which instruction should the nurse provide to this client's caregivers? • Offer the morning dose of the medicine before breakfast. • Have the client chew the pill if it is difficult to swallow. • Encourage high energy fluid intake by providing sports drinks or sodas. • Report symptoms of hypothyroidism such as fatigue and constipation. ️ Correct Answer: Report symptoms of hypothyroidism such as fatigue and constipation.

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Uploaded on
April 25, 2025
Number of pages
15
Written in
2024/2025
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Exam (elaborations)
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  • hesi pharm

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HESI pharm practice test 1
Exam Questions with
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Question:
The first-pass effect occurs when hepatic metabolism decreases the
bioavailability of a drug. Oral forms of medications are processed
through the GI tract, absorbed through the small intestines, and
undergo the first-pass effect in the liver in which some of the active
ingredients are removed from the drug before it reaches the intended
site of action. Which route should the nurse clarify with the healthcare
provider prior to administering a drug with a high first-pass effect?
• Oral
• Buccal
• Sublingual
• Intravenous

, Correct Answer:
Oral




Question:
With the loss of exocrine function for a client with chronic pancreatitis,
replacement of pancreatic enzymes using pancrelipase (Pancrease)
becomes necessary. Diarrhea and steatorrhea (fatty stools) indicate
insufficient pancreatic enzymes are present to digest dietary fats and
other nutrients, so pancrelipase, a fat-digesting enzyme, should be
consumed with any type of food. Which instruction is most important
for the nurse to include in this client's teaching?
• Avoid prolonged exposure to direct sunlight
• Stay away from products containing alcohol
• Ingest 8 oz of grapefruit juice with the medication
• Take the medication when consuming food

Correct Answer:
Take the medication when consuming food


Question:
Beta-blockers are used to inhibit aqueous humor production, with the
goal of reducing intraocular pressure. What is the effect of beta-
blocking agents when used for treatment of glaucoma?
• Inhibiting aqueous humor production

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