4/22/25, 8:37 AM NBME CBSE: PUBLIC HEALTH SCIENCES PT. 1 ALL QUESTIONS AND WELL ELABORATED ANSWERS TOP RATED VERSIO…
NBME CBSE: PUBLIC HEALTH SCIENCES PT. 1 ALL
UPDATED QUESTIONS AND WELL DETAILED
ANSWERS COMPLETE DOCUMENT ALREADY GRADED
A+\\ASSURED PASS
What is a case series?
Choose matching definition
Description of clinical
A report on the financial costs
findings/symptoms for several 2 associated with treating multiple
1
patients with the same diagnosis, patients.
treatment, or outcome.
A study that only focuses on one An analysis of laboratory results
3
patient with a unique diagnosis. 4 from various patients without
considering their symptoms.
… 1/17
,4/22/25, 8:38 AM NBME CBSE: PUBLIC HEALTH SCIENCES PT. 1 ALL QUESTIONS AND WELL ELABORATED ANSWERS TOP RATED VERSIO…
Description of clinical findings/symptoms for several
What is a case series? patients with the same diagnosis, treatment, or
outcome.
What is a cross-sectional Assesses the frequency of disease and risk-related
study? factors in the present.
Retrospectively compares a group of people with a
What is a case-control
disease to a group without the disease to determine if
study?
odds of prior exposure/risk factor differ.
Compares a group of people with a given
exposure/risk factor to a group without exposure to
What is a cohort study?
determine if the exposure/risk factor is associated
with later development of disease.
Compares the frequency with which both
What is a twin monozygotic twins vs both dizygotic twins develop
concordance study? the same disease to measure heritability and influence
of environmental factors.
Compares behavioral traits/genetics in siblings raised
What is an adoption
by biological vs adoptive parents to measure
study?
heritability and influence of environmental factors.
Compares the frequency of disease and risk-related
What is an ecological
factors across populations to measure population
study?
data (not applicable to individuals).
What is a clinic therapeutic An experimental study involving humans that
trial? compares the benefits of two or more interventions.
What are the criteria for a Randomized, controlled, and double-blinded
high-quality clinical trial?
What is a crossover clinical Compares the effect of multiple treatments on a
trial? subject
… 2/17
, 4/22/25, 8:38 AM NBME CBSE: PUBLIC HEALTH SCIENCES PT. 1 ALL QUESTIONS AND WELL ELABORATED ANSWERS TOP RATED VERSIO…
To avoid bias
What is the purpose of
randomizing the order of
treatments in a crossover
trial?
A period between treatments to eliminate any
What is a washout period
lingering effects
in a crossover trial?
Subjects serve as their own controls
What is the advantage of
using a crossover trial?
Analyzing all subjects according to their original
What is the intention-to-
assigned treatment
treat analysis?
To avoid bias from attrition, crossover, and
What is the purpose of
noncompliance
intention-to-treat analysis?
May dilute the true effects of the intervention
What is the disadvantage
of intention-to-treat
analysis?
Analyzing subjects according to the treatment they
What is the as-treated
actually received
analysis?
Increases the risk of bias
What is the disadvantage
of as-treated analysis?
Excluding subjects who did not complete the
What is the per-protocol
originally assigned treatment
analysis?
Increases the risk of bias
What is the disadvantage
of per-protocol analysis?
Preclinical, Phase 0, Phase 1, Phase 2, Phase 3, Phase 4
What are the five phases
of clinical trials?
Testing the drug in lab animals and in vitro
What happens in the
preclinical phase of
clinical trials?
Initial assessment of pharmacokinetics and
What happens in Phase 0
pharmacodynamics via microdosing
of clinical trials?
… 3/17
NBME CBSE: PUBLIC HEALTH SCIENCES PT. 1 ALL
UPDATED QUESTIONS AND WELL DETAILED
ANSWERS COMPLETE DOCUMENT ALREADY GRADED
A+\\ASSURED PASS
What is a case series?
Choose matching definition
Description of clinical
A report on the financial costs
findings/symptoms for several 2 associated with treating multiple
1
patients with the same diagnosis, patients.
treatment, or outcome.
A study that only focuses on one An analysis of laboratory results
3
patient with a unique diagnosis. 4 from various patients without
considering their symptoms.
… 1/17
,4/22/25, 8:38 AM NBME CBSE: PUBLIC HEALTH SCIENCES PT. 1 ALL QUESTIONS AND WELL ELABORATED ANSWERS TOP RATED VERSIO…
Description of clinical findings/symptoms for several
What is a case series? patients with the same diagnosis, treatment, or
outcome.
What is a cross-sectional Assesses the frequency of disease and risk-related
study? factors in the present.
Retrospectively compares a group of people with a
What is a case-control
disease to a group without the disease to determine if
study?
odds of prior exposure/risk factor differ.
Compares a group of people with a given
exposure/risk factor to a group without exposure to
What is a cohort study?
determine if the exposure/risk factor is associated
with later development of disease.
Compares the frequency with which both
What is a twin monozygotic twins vs both dizygotic twins develop
concordance study? the same disease to measure heritability and influence
of environmental factors.
Compares behavioral traits/genetics in siblings raised
What is an adoption
by biological vs adoptive parents to measure
study?
heritability and influence of environmental factors.
Compares the frequency of disease and risk-related
What is an ecological
factors across populations to measure population
study?
data (not applicable to individuals).
What is a clinic therapeutic An experimental study involving humans that
trial? compares the benefits of two or more interventions.
What are the criteria for a Randomized, controlled, and double-blinded
high-quality clinical trial?
What is a crossover clinical Compares the effect of multiple treatments on a
trial? subject
… 2/17
, 4/22/25, 8:38 AM NBME CBSE: PUBLIC HEALTH SCIENCES PT. 1 ALL QUESTIONS AND WELL ELABORATED ANSWERS TOP RATED VERSIO…
To avoid bias
What is the purpose of
randomizing the order of
treatments in a crossover
trial?
A period between treatments to eliminate any
What is a washout period
lingering effects
in a crossover trial?
Subjects serve as their own controls
What is the advantage of
using a crossover trial?
Analyzing all subjects according to their original
What is the intention-to-
assigned treatment
treat analysis?
To avoid bias from attrition, crossover, and
What is the purpose of
noncompliance
intention-to-treat analysis?
May dilute the true effects of the intervention
What is the disadvantage
of intention-to-treat
analysis?
Analyzing subjects according to the treatment they
What is the as-treated
actually received
analysis?
Increases the risk of bias
What is the disadvantage
of as-treated analysis?
Excluding subjects who did not complete the
What is the per-protocol
originally assigned treatment
analysis?
Increases the risk of bias
What is the disadvantage
of per-protocol analysis?
Preclinical, Phase 0, Phase 1, Phase 2, Phase 3, Phase 4
What are the five phases
of clinical trials?
Testing the drug in lab animals and in vitro
What happens in the
preclinical phase of
clinical trials?
Initial assessment of pharmacokinetics and
What happens in Phase 0
pharmacodynamics via microdosing
of clinical trials?
… 3/17
