ga ga ga ga ga ga ga ga ga
Test Bank
ga ga
,Psychopharmacology Drugs the Brain And Behavior 3rd Edition meyer Nursing ga ga ga ga ga ga ga ga ga
Test Bank
ga ga
Test Bank ga
to accompany
ga
Psychopharmacology, Third Edition ga ga
Meyer • Quenzer ga ga
Chapter 1: Principles of Pharmacology ga ga ga ga
Multiple Choice ga
1. ga refer(s) to specific molecular changes that occur when a drug binds to a ga ga ga ga ga ga ga ga ga ga ga ga
particular target site or receptor, while
ga are the resulting widespread
ga ga ga ga ga ga ga ga
alterationsin function.
ga ga ga
a. Drug action; therapeutic effects ga ga ga
b. Side effects; drug effects ga ga ga
c. Therapeutic effects; side effects ga ga ga
d. Drug action; drug effects ga ga ga
Answer: d ga
Textbook Reference: Pharmacology: The Science of Drug Action
ga ga ga ga ga ga ga
2. After drug administration has occurred, the amount of drug in the blood that is free
ga ga ga ga ga ga ga ga ga ga ga ga ga ga
tobind at specific target sites is referred to as
ga ga ga ga ga ga ga ga ga ga
a. the therapeutic dose.
ga ga
b. first-pass effects. ga
c. bioavailability.
d. ED50.
Answer: c ga
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ga ga ga ga ga ga
3. The specific molecular changes that occur when a drug binds to a particular target
ga ga ga ga ga ga ga ga ga ga ga ga ga
siteor receptor are referred to as
ga ga ga ga ga ga ga
a. drug effects. ga
b. drug action. ga
c. side effects. ga
d. placebo effects. ga
Answer: b ga
Textbook Reference: Pharmacology: The Science of Drug Action
ga ga ga ga ga ga ga
4. Which of the following is not a possible explanation for placebo effects?
ga ga ga ga ga ga ga ga ga ga ga
a. Pavlovian conditioning ga
b. Genetic variation ga
c. Drug competition ga
d. Expectation of outcome ga ga
Answer: c ga
Textbook Reference: Pharmacology: The Science of Drug Action
ga ga ga ga ga ga ga
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,Psychopharmacology Drugs the Brain And Behavior 3rd Edition meyer Nursing ga ga ga ga ga ga ga ga ga
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ga ga
5. The administration of oxytocin has been proposed as a treatment for autism. ga ga ga ga ga ga ga ga ga ga
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c ga
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ga ga ga ga ga ga
6. Which factor does not affect the pharmacokinetics of a drug?
ga ga ga ga ga ga ga ga ga
a. Route of administration ga ga
b. Lipid solubility ga
c. Depot binding ga
d. Drug action ga
Answer: d ga
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ga ga ga ga ga ga
7. First-pass metabolism occurs when drugs are taken ga ga ga ga ga ga
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a ga
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ga ga ga ga ga ga
8. The area postrema is one area in the brain where the
ga ga is not complete. ga ga ga ga ga ga ga ga ga ga
a. cerebrospinal fluid ga
b. blood–brain barrier ga
c. choroid plexus ga
d. phospholipid membrane ga
Answer: b ga
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ga ga ga ga ga ga
9. First-pass metabolism occurs with orally administered drugs because
ga ga ga ga ga ga ga
a. their absorption is slowed by food.
ga ga ga ga ga
b. drugs absorbed into the bloodstream from the stomach go to the liver on the way
ga ga ga ga ga ga ga ga ga ga ga ga ga ga
togeneral circulation.
ga ga ga
c. drugs must first survive the acidic environment of the stomach.
ga ga ga ga ga ga ga ga ga
d. salivary enzymes in the mouth begin the process of metabolism.
ga ga ga ga ga ga ga ga ga
Answer: b ga
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ga ga ga ga ga ga
10. Toxic substances in the blood trigger a vomiting response by activating the
ga ga ga ga ga ga ga ga ga ga ga
a. blood–brain barrier. ga
b. choroid plexus. ga
c. area postrema.
ga
d. median eminence. ga
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, Psychopharmacology Drugs the Brain And Behavior 3rd Edition meyer Nursing ga ga ga ga ga ga ga ga ga
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ga ga
Answer: c ga
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ga ga ga ga ga ga
11. Drugs administered _ have the most rapid onset of action.
ga ga ga ga ga ga ga ga
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d ga
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ga ga ga ga ga ga
12. Ionization of a drug depends on the of the solution and the
ga ga ga ga ga ga ga ga ga ga of
thedrug.
ga ga
a. pH; pKa ga
b. pKa; pH ga
c. concentration; lipid solubility ga ga
d. pH; concentrationga
Answer: a ga
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ga ga ga ga ga ga
13. The absorption of a drug depends on all of the following except
ga ga ga ga ga ga ga ga ga ga ga
a. lipid solubility. ga
b. ionization.
c. body temperature. ga
d. the concentration of the drug.
ga ga ga ga
Answer: c ga
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ga ga ga ga ga ga
14. Drugs that are should be avoided by women of childbearing age.
ga ga ga ga ga ga ga ga ga
a. teratogenic
b. able to cross the placental barrier
ga ga ga ga ga
c. psychoactive
d. highly lipid-soluble ga
Answer: a ga
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ga ga ga ga ga ga
15. Agents that induce developmental abnormalities in a fetus are known as
ga ga ga ga ga ga ga ga ga ga
a. psychoactive drugs. ga
b. illicit drugs. ga
c. teratogens.
d. placental drugs. ga
Answer: c ga
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
ga ga ga ga ga ga
16. Depot binding is said to occur when drugsga ga ga ga ga ga ga
a. bind to their target sites.
ga ga ga ga
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