UNE MEDICAL BIOCHEMISTRY UNIT 1 TEST QUESTIONS AND ANSWERS
2024/2025 LATEST UPDATED A COMPLETE EXAM ALL ANSWERS 100%
CORRECT BEST RATED A+ FOR SUCCESS
Children with cystinosis have growth delay and renal issues to to accumulation of cysteine in
cellular lysosomes. The defect involves a specific lysosomal membrane receptor that facilitates
cysteine removal from the cell. An effective therapy involves administration of a drug with a
similar structure to cysteine. This therapy reflects the general principle that competitive
inhibitors typically resemble the structure of which of the following?
a) substrates or ligands that bind the active site
b) enzyme or receptor protein
c) enzyme reaction products
d) the cofactor - CORRECT ANSWERS substrates or ligands that bind the active site
A new enzyme is discovered that increases in activity when it is phosphorylated on an exposed
tyrosine. Phosphorylation of this amino acid is classified as which of the following?
a) feedback inhibition
b) transcriptional activation
c) covalent modification
d) increased protein ubiquitination - CORRECT ANSWERS covalent modification
Which of the following is an example of enzyme regulation through covalent modification?
a) binding of GTP to a monomeric G-protein
b) phosphorylation of muscle glycogen
c) digestion of misfolded proteins by lysosomes
d) cleavage of chymotrypsinogen to chymotrypsin - CORRECT ANSWERS
phosphorylation of muscle glycogen phosphorylase
, UNE MEDICAL BIOCHEMISTRY UNIT 1 TEST QUESTIONS AND ANSWERS
2024/2025 LATEST UPDATED A COMPLETE EXAM ALL ANSWERS 100%
CORRECT BEST RATED A+ FOR SUCCESS
Under low energy conditions, AMP will bind to phosphofructokinase I and glycogen
phosphorylase. This is an example of which of the follow types of enzyme regulation?
a) competitive inhibition
b) covalent modification
c) allosteric inhibition
d) allosteric activation - CORRECT ANSWERS allosteric activation
The following represents a series of reactions. As levels of B increase, this will decrease the
conversion of S3 to B. Which of the following best describes this type of regulation in a
biosynthetic pathway?
a) feedback inhibition
b) feedforward activation
c) covalent regulation
d) inducible regulation - CORRECT ANSWERS feedback inhibition
The association of DNA and histones can be modified by histone acetylation. A decrease in
histone acetylation will have which of the following impacts on the assocation of DNA and
histones?
a) increase DNA:histone association
b) decrease DNA:histone association
c) have no effect - CORRECT ANSWERS Increase DNA:histone association
If a mutation is made within the active site of an enzyme resulting in a decrease of it's Km value,
which of the following will be true with respect to enzyme kinetics?
2024/2025 LATEST UPDATED A COMPLETE EXAM ALL ANSWERS 100%
CORRECT BEST RATED A+ FOR SUCCESS
Children with cystinosis have growth delay and renal issues to to accumulation of cysteine in
cellular lysosomes. The defect involves a specific lysosomal membrane receptor that facilitates
cysteine removal from the cell. An effective therapy involves administration of a drug with a
similar structure to cysteine. This therapy reflects the general principle that competitive
inhibitors typically resemble the structure of which of the following?
a) substrates or ligands that bind the active site
b) enzyme or receptor protein
c) enzyme reaction products
d) the cofactor - CORRECT ANSWERS substrates or ligands that bind the active site
A new enzyme is discovered that increases in activity when it is phosphorylated on an exposed
tyrosine. Phosphorylation of this amino acid is classified as which of the following?
a) feedback inhibition
b) transcriptional activation
c) covalent modification
d) increased protein ubiquitination - CORRECT ANSWERS covalent modification
Which of the following is an example of enzyme regulation through covalent modification?
a) binding of GTP to a monomeric G-protein
b) phosphorylation of muscle glycogen
c) digestion of misfolded proteins by lysosomes
d) cleavage of chymotrypsinogen to chymotrypsin - CORRECT ANSWERS
phosphorylation of muscle glycogen phosphorylase
, UNE MEDICAL BIOCHEMISTRY UNIT 1 TEST QUESTIONS AND ANSWERS
2024/2025 LATEST UPDATED A COMPLETE EXAM ALL ANSWERS 100%
CORRECT BEST RATED A+ FOR SUCCESS
Under low energy conditions, AMP will bind to phosphofructokinase I and glycogen
phosphorylase. This is an example of which of the follow types of enzyme regulation?
a) competitive inhibition
b) covalent modification
c) allosteric inhibition
d) allosteric activation - CORRECT ANSWERS allosteric activation
The following represents a series of reactions. As levels of B increase, this will decrease the
conversion of S3 to B. Which of the following best describes this type of regulation in a
biosynthetic pathway?
a) feedback inhibition
b) feedforward activation
c) covalent regulation
d) inducible regulation - CORRECT ANSWERS feedback inhibition
The association of DNA and histones can be modified by histone acetylation. A decrease in
histone acetylation will have which of the following impacts on the assocation of DNA and
histones?
a) increase DNA:histone association
b) decrease DNA:histone association
c) have no effect - CORRECT ANSWERS Increase DNA:histone association
If a mutation is made within the active site of an enzyme resulting in a decrease of it's Km value,
which of the following will be true with respect to enzyme kinetics?
