COMLEX LEVEL 1 EXAM WITH
CORRECT ACTUAL QUESTIONS AND
CORRECTLY WELL DEFINED ANSWERS
LATEST 2025 - 2026 ALREADY GRADED A+
Legionella pneumophila - ANSWERS-aerobic, *facultatively
intracellular*, gram negative rods that contaminate water supplies
and cause atypical pneumonia via infection of alveolar macrophages
25-hydroxycholecalciferol - ANSWERS-if you have kidney issues what
product of vitamin D metabolism will be built up?
Streptococcus sanguinis (S. viridans) - ANSWERS-what causes small
vegetations on the aortic valve after tooth extraction?
posterior limb of internal capsule - ANSWERS-affected in
spontaneous hypertensive hemorrhage and contains the descending
,corticospinal tract of the upper motor neurons for the extremities as
well as all ascending somatosensory pathways for the body and face
gene of the internal capsule - ANSWERS-contains the descending
corticobulbar tract and upper motor neurons for the face
Osteoarthritis (OA) - ANSWERS-Decrease in joint space due to
cartilage erosion and bony sclerosis
affects the PIP( Bouchard's nodes) and DIP (Herberden's nodes)
joints, does not affect the MCPs
affects large, weight bearing joints like the hips and knees
causes morning stiffness lasting approximately 15 minutes
rheumatoid arthritis - ANSWERS-results in inflammatory pannus
formation (anti-CCP antibodies)
affects the MCP and PIP joints and spares the DIP joints ( Swann neck
and boutonniere)
has morning stiffness greater than 30 minutes
,have inflammatory markers such as CRP or ESR
Would there be signs of hypocalcemia--> tetany, paresthesias,
abdominal cramps?
T5-T11 - ANSWERS-where would you find a viserosomatic reflex
resulting in placatory changes of the pancreas?
Deferoxamine (Desferal) - ANSWERS-iron chelating agent used in the
treatment of iron intoxication
short leg syndrome - ANSWERS-when a patient presents with a
flexible scoliotic curve it is important to evaluate for...
inferior trunk--> encompasses broadmann areas 22,39,40 which are
in the temporal region - ANSWERS-Infarct to what trunk of the Left
MCA results in Wernicke's aphasia?
Superior division--> encompasses brooks area, frontal eye field,
primary motor cortex and primary somatosensory cortex - ANSWERS-
Infarct to what trunk of the Left MCA results in Broca's aphasia?
Osteosarcoma - ANSWERS-bone tumor that is present in young adult
males that involves the metaphysis of the long bones
, Ewing's sarcoma t(11;22) - ANSWERS-bone tumor that is present in
young adult males that involves the *diaphysis(mid-shaft)* of the
long bones.
fibrosarcoma - ANSWERS-malignant fibroblasts within a collagenous
matrix
chondrosarcoma - ANSWERS-osseous sarcomas that affect older
patients and has a predilection for flat bones in the *shoulders and
pelvis*
tyrosine, due to a defect in phenylalanine hydroxylase - ANSWERS-
PKU presents as failure to thrive, mental retardation, gapped teeth,
etc. What is the amino acid that needs to be supplemented due to a
defect in what enzyme?
Rib 2 - ANSWERS-where does the posterior scalene attach to?
Paclitaxel - ANSWERS-used in the treatment of breast and ovarian
cancer
MOA: hyper stabilization of polymerized microtubules--> prevents
the breakdown of the mitotic spindle
restrictive barrier - ANSWERS-maximum distance a patient can
actually move a joint, can be pathologic
CORRECT ACTUAL QUESTIONS AND
CORRECTLY WELL DEFINED ANSWERS
LATEST 2025 - 2026 ALREADY GRADED A+
Legionella pneumophila - ANSWERS-aerobic, *facultatively
intracellular*, gram negative rods that contaminate water supplies
and cause atypical pneumonia via infection of alveolar macrophages
25-hydroxycholecalciferol - ANSWERS-if you have kidney issues what
product of vitamin D metabolism will be built up?
Streptococcus sanguinis (S. viridans) - ANSWERS-what causes small
vegetations on the aortic valve after tooth extraction?
posterior limb of internal capsule - ANSWERS-affected in
spontaneous hypertensive hemorrhage and contains the descending
,corticospinal tract of the upper motor neurons for the extremities as
well as all ascending somatosensory pathways for the body and face
gene of the internal capsule - ANSWERS-contains the descending
corticobulbar tract and upper motor neurons for the face
Osteoarthritis (OA) - ANSWERS-Decrease in joint space due to
cartilage erosion and bony sclerosis
affects the PIP( Bouchard's nodes) and DIP (Herberden's nodes)
joints, does not affect the MCPs
affects large, weight bearing joints like the hips and knees
causes morning stiffness lasting approximately 15 minutes
rheumatoid arthritis - ANSWERS-results in inflammatory pannus
formation (anti-CCP antibodies)
affects the MCP and PIP joints and spares the DIP joints ( Swann neck
and boutonniere)
has morning stiffness greater than 30 minutes
,have inflammatory markers such as CRP or ESR
Would there be signs of hypocalcemia--> tetany, paresthesias,
abdominal cramps?
T5-T11 - ANSWERS-where would you find a viserosomatic reflex
resulting in placatory changes of the pancreas?
Deferoxamine (Desferal) - ANSWERS-iron chelating agent used in the
treatment of iron intoxication
short leg syndrome - ANSWERS-when a patient presents with a
flexible scoliotic curve it is important to evaluate for...
inferior trunk--> encompasses broadmann areas 22,39,40 which are
in the temporal region - ANSWERS-Infarct to what trunk of the Left
MCA results in Wernicke's aphasia?
Superior division--> encompasses brooks area, frontal eye field,
primary motor cortex and primary somatosensory cortex - ANSWERS-
Infarct to what trunk of the Left MCA results in Broca's aphasia?
Osteosarcoma - ANSWERS-bone tumor that is present in young adult
males that involves the metaphysis of the long bones
, Ewing's sarcoma t(11;22) - ANSWERS-bone tumor that is present in
young adult males that involves the *diaphysis(mid-shaft)* of the
long bones.
fibrosarcoma - ANSWERS-malignant fibroblasts within a collagenous
matrix
chondrosarcoma - ANSWERS-osseous sarcomas that affect older
patients and has a predilection for flat bones in the *shoulders and
pelvis*
tyrosine, due to a defect in phenylalanine hydroxylase - ANSWERS-
PKU presents as failure to thrive, mental retardation, gapped teeth,
etc. What is the amino acid that needs to be supplemented due to a
defect in what enzyme?
Rib 2 - ANSWERS-where does the posterior scalene attach to?
Paclitaxel - ANSWERS-used in the treatment of breast and ovarian
cancer
MOA: hyper stabilization of polymerized microtubules--> prevents
the breakdown of the mitotic spindle
restrictive barrier - ANSWERS-maximum distance a patient can
actually move a joint, can be pathologic
