Lab
Name
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OL Lab 3: Cellular Respiration: Measuring energy consumption during exercise
Learning Objectives:
• Explain the structural changes of glucose and ATP during glycolysis.
• Analyze blood glucose and lactic acid concentrations of athletes before and
after exercise.
• Determine electron carrier products of the Krebs cycle.
• Understand the role of the electron transport chain in generating ATP.
• Experiment on oxygen consumption in mice at various exercise intensities.
Cellular respiration is a multistep process by which the cells create energy in the form of ATP to
drive its cellular activities. In this simulation, you will learn the differences between aerobic and
anaerobic respiration by studying glucose metabolism. You will explore the three stages of
cellular respiration: glycolysis, the Krebs cycle, and the electron transport chain.
In this simulation, you will use a mouse model to understand the cellular respiration of
basketball players. The experimental exercise data collected from the mouse model and
respirometry will be compared to the blood glucose and lactic acid concentrations of the
basketball players throughout the game. You will also, be able to explore the cellular processes
that occur within the mitochondria and how it contributes to ATP generation. Are you ready to
apply your knowledge on glycolysis, the Krebs’s cycle, and the electron transport chain to help
basketball players perform their best during the game?