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Test bank for Abrams Clinical Drug Therapy 12th edition | Nursing Practice | by Geralyn Frandsen, Sandra Smith Pennington | 2025 updated

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Test bank for Abrams Clinical Drug Therapy 12th edition Complete 2025 edition By Geralyn Frandsen, Sandra Smith Pennington

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,Chapter 1, The Foundation of Pharmacology: Quality and Safety

1. A woman diagnosed with obsessive–compulsive disorder has been prescribed
oral paroxetine hydrochloride. What is the expected effect for this prescription?
A. Curative effect on symptoms
B. Systemic effect on symptoms
C. Local effect on symptoms
D. Parenteral effect on symptoms
ANS: B
Rationale: Drugs that produce systemic effects are taken into the body, circulated through
the bloodstream to their sites of action in various body tissues, and eventually eliminated
from the body. Curative agents are given to cure a disease process. In this case, paroxetine
hydrochloride will control the symptoms but not cure the disorder. Drugs with local effects,
such as sunscreen and local anesthetics, act mainly at the site of application. Paroxetine
hydrochloride is not administered parenterally. Parenteral agents are administered
subcutaneously, intramuscularly, or intravenously.

PTS: 1 REF: p. 3, Introduction OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice

2. A client has been prescribed an antibiotic. This medication is a naturally occurring
substance that has been cheGmRicAalDlyEmSoBdOifOieSd.TW.ChaOt Mi s
another name for this type of medication?
A. Synthetic drug
B. Semisynthetic drug
C. Biotechnology drug
D. Prototype drug
ANS: B
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances
that have been chemically modified. Synthetic drugs are more standardized in their
chemical characteristics, more consistent in their effects, and less likely to produce allergic
reactions. Biotechnology drugs involve manipulating DNA and RNA and recombining
genes into hybrid molecules that can be inserted into living organisms. Prototype drugs are
the first drug of a particular group to be developed.

PTS: 1 REF: p. 3, Drug Sources OBJ: 1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
Therapies TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice

3. Which classification applies to morphine?
A. Central nervous system depressant
B. Central nervous system stimulant




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, C. Anti-inflammatory
D. Antihypertensive
ANS: A
Rationale: Drugs are classified according to their effects on particular body systems, their therapeutic
uses, and their chemical characteristics. Morphine is classified as a central nervous system
depressant and will produce this effect in the client. A central nervous system stimulant
increases attention and raises mood. An anti-inflammatory agent decreases inflammation at
the site of tissue or joint inflammation. An antihypertensive agent reduces blood pressure.

PTS: 1 REF: p. 3, Drug Classifications and Prototypes OBJ:
1
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies TOP:
Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Remember NOT: Multiple Choice

4. A client is administered amoxicillin. The generic name of this medication belongs to
which drug group?
A. Selective serotonin reuptake inhibitors
B. Diuretics
C. Penicillins
D. ACE inhibitors
ANS: C
Rationale: The generic name often indicates the drug group (e.g., drugs with generic names ending in
GRADESBOOST.CO
“cillin” are penicillins). Selective serotonin reuptake inhibitors are medications that have
M
antidepressant effects; SSRI is a broad classification, not a generic name. Diuretics are
medications that increase urine output; diuretic is a broad classification, not a generic name.
ACE inhibitor is the broad classification for the angiotensin receptor blockers, not the
generic name.

PTS: 1 REF: p. 3, Drug Names OBJ: 2
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies TOP:
Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice

5. The administration of diphenhydramine is regulated by which U.S. government agency?
A. Public Health Service
B. Federal Trade Commission
C. Occupational Safety and Health Administration
D. Food and Drug
Administration ANS: D




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, Rationale: The Food and Drug Administration approves drugs for over-the-counter availability,
including the transfer of drugs from prescription to OTC status, and may require clinical
trials to determine the safety and effectiveness of OTC use. The Public Health Service is
regulated by the state to maintain the health of individual citizens of the state. The Federal
Trade Commission regulates imports and exports throughout the nation. The Occupational
Safety and Health Administration regulates safety within the workplace.

PTS: 1 REF: p. 4, Prescription and Nonprescription Drugs OBJ:
4
NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies TOP:
Chapter: 1: The Foundation of Pharmacology: Quality and Safety
KEY: Integrated Process: Nursing Process
BLM: Cognitive Level: Understand NOT: Multiple Choice




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