USA NU578 Exam 3 Questions with Detailed Verified Answers (100% Correct Answers) /Already Graded A+

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USA NU578 Exam 3 Questions with
Detailed Verified Answers (100% Correct
Answers) /Already Graded A+
What is the moa for diuretics?

Ans: Affects Maintenance of ecf volume and composition


What is the Path that urine takes through the nephron

Ans: Glomerulus▶️Prox convol tube▶️Loop of Henle: Descrnding
limb▶️Ascending limb▶️DCT▶️Collecting duct


What is the site of action for osmotic diuretics like

Mannitol?

Ans: Proximal convoluted tubule


What is the Site of action for Thiazide diuretics like

HCTZ?

Ans: Early distal convoluted tubule


What is the (site of action for Potassium sparing diuretics like

Spironolactone?

Ans: Late distal convoluted tubule and collecting duct (distal nephron)

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What is the sote of action for Loop diuretics like

Furosemide?

Ans: Loop of Henle


Loop diuretics cause drug toxicity due to increased Na+ excretion.

Ans: Lithium excretion is decreased with hyponatremia and causes lithium
toxicity.


Nephron order of diuretic action

Ans: Osmotics▶️Loops
▶️Thiazides▶️K+ sparing


PCT (proximal convoluted tubule)

Ans: High resorptive capacity. About 65% of filtered Na+ and Cl resorbed
here. Urine is isotonic


Freely permeable to water

Ans: Descending limb loop of Henle


Na/K exchange: Na+ reabsorbed, K+ excreted stimulated by

Ans: Distal nephron: late DCT/CD


Causes transient deafness

Ans: Furosemide


Only diuretic class that is ototoxic