Nursing pharmacology lee hays
mccuistion chapter 1 drug action
Absorption - ANS-Is the movement of drug particles from the G.I. tract to body fluids by
passive absorption active or Pinocytosis
\Absorption is reduced if - ANS-If the villi are decreased
\Absorption is slower in which tissue - ANS-Subcutaneous tissue
\Active absorption 003 - ANS-Requires a carrier such as an enzyme or protein to move the
drug against the concentration gradient
\Adverse reactions 011 - ANS-A result of drug therapy that is neither intended nor expected
in normal therapeutic use and that causes significant sometimes life-threatening conditions
\Agonists 008 - ANS-Drugs that produce a response
\All drugs have a - ANS-Maximum drug effect or maximum Efficacy
\Antagonists 008 - ANS-Drugs that block a response
\Aspirin, or weak acid, is excreted rapidly in ....... Urine - ANS-Alkaline
\Because of a high first pass metabolism, oral doses could be higher then the same drugs
dose for IV use. True or false - ANS-True
\Bioavailability 004 - ANS-A subcategory of absorption, the percentage of the administer
drugs does it reaches the systemic circulation
\Bloodflow, pain, stress, hunger, fasting, food and pH all - ANS-Effect drug absorption
\Common tests used to determine renal function are - ANS-Creatinine clearance
And blood urea nitrogen BUN
\Creatinine clearance 007 - ANS-The volume of serum or plasma that would be cleared of
creatinine by one minutes excretion of urine
\Disintegration 003 - ANS-The act or process of decaying or disintegrating
\Dissolution 003 - ANS-Is the dissolving of the smaller particles in the G.I. fluid before
absorption
\Distribution 004 - ANS-Is the process by which the drug becomes available to body fluids
and body tissues
\Drug distribution is influenced by - ANS-Bloodflow, the drugs affinity to the tissue, and the
protein-binding effect
\Drugs given IM are absorbed faster and muscles that have what - ANS-More blood vessels
\Drugs that have extensive first pass metabolismare not given orally because - ANS-They're
not given orally because most of the dose would be destroyed by the first pass metabolism
\Duration of action 007 - ANS-Is the length of time the drug has a pharmacologic effect
\Elimination 007 - ANS-The action of the kidneys filtering free unbound drugs, water soluble
drugs, and drugs that are unchanged and in which they leave the body in the urine.
\Enteric coated drugs resist disintegration in the gastric acid of the stomach so disintegration
does not occur until the drug reaches the what - ANS-Disintegration does not occur until the
drug reaches the alkaline environment of the small intestine.
\Enteric coated tablets or capsules and sustained release capsules should not be what -
ANS-They should not be crushed because crushing them would alter the place and time of
absorption
mccuistion chapter 1 drug action
Absorption - ANS-Is the movement of drug particles from the G.I. tract to body fluids by
passive absorption active or Pinocytosis
\Absorption is reduced if - ANS-If the villi are decreased
\Absorption is slower in which tissue - ANS-Subcutaneous tissue
\Active absorption 003 - ANS-Requires a carrier such as an enzyme or protein to move the
drug against the concentration gradient
\Adverse reactions 011 - ANS-A result of drug therapy that is neither intended nor expected
in normal therapeutic use and that causes significant sometimes life-threatening conditions
\Agonists 008 - ANS-Drugs that produce a response
\All drugs have a - ANS-Maximum drug effect or maximum Efficacy
\Antagonists 008 - ANS-Drugs that block a response
\Aspirin, or weak acid, is excreted rapidly in ....... Urine - ANS-Alkaline
\Because of a high first pass metabolism, oral doses could be higher then the same drugs
dose for IV use. True or false - ANS-True
\Bioavailability 004 - ANS-A subcategory of absorption, the percentage of the administer
drugs does it reaches the systemic circulation
\Bloodflow, pain, stress, hunger, fasting, food and pH all - ANS-Effect drug absorption
\Common tests used to determine renal function are - ANS-Creatinine clearance
And blood urea nitrogen BUN
\Creatinine clearance 007 - ANS-The volume of serum or plasma that would be cleared of
creatinine by one minutes excretion of urine
\Disintegration 003 - ANS-The act or process of decaying or disintegrating
\Dissolution 003 - ANS-Is the dissolving of the smaller particles in the G.I. fluid before
absorption
\Distribution 004 - ANS-Is the process by which the drug becomes available to body fluids
and body tissues
\Drug distribution is influenced by - ANS-Bloodflow, the drugs affinity to the tissue, and the
protein-binding effect
\Drugs given IM are absorbed faster and muscles that have what - ANS-More blood vessels
\Drugs that have extensive first pass metabolismare not given orally because - ANS-They're
not given orally because most of the dose would be destroyed by the first pass metabolism
\Duration of action 007 - ANS-Is the length of time the drug has a pharmacologic effect
\Elimination 007 - ANS-The action of the kidneys filtering free unbound drugs, water soluble
drugs, and drugs that are unchanged and in which they leave the body in the urine.
\Enteric coated drugs resist disintegration in the gastric acid of the stomach so disintegration
does not occur until the drug reaches the what - ANS-Disintegration does not occur until the
drug reaches the alkaline environment of the small intestine.
\Enteric coated tablets or capsules and sustained release capsules should not be what -
ANS-They should not be crushed because crushing them would alter the place and time of
absorption
