Wilkes NURS 533 Test 1 practice questions (GI,
diabetes, mens/womens health, MDD, GAD, Insomnia)
Actual Test Questions with Detailed Verified Answers &
Rationales / Already Graded A
Terms in this set (210)
1. Which one of the Answer: C
following GERD symptom is
considered atypical and Option C: Correct. Wheezing is an atypical symptom and
requires further diagnostic may be a contributing factor in certain patients with
asthma.
evaluation? A. Heartburn
B. Regurgitation
C. Wheezing
D. None of the
abovesymptoms is
considered atypical
Answer: A
2. Which of the following Option A: Correct. Dexlansoprazole can be taken without
represents the correct order regard to meals.
of gastric acid suppression Option B: Incorrect. Lansoprazole should be taken 30 to 60
from most suppression to minutes prior to a meal.
least suppression? Option C: Incorrect. Omeprazole should be taken 30 to 60
a PPI > H2RA > Antacid b minutes prior to a meal.
PPI > Antacid > H2RA c Option D: Incorrect. Pantoprazole should be taken 30 to 60
Antacid > H2RA > PPI d minutes prior to a meal.
H2RA > PPI > Antacid
,3. What would be the best Answer: D
initial pharmacologic option Option A: Incorrect. The patient has symptoms only once a
in addition to lifestyle week, so a twice-daily PPI is not indicated. Option B: Incorrect.
modification for a patient The patient has symptoms only once a week, so a daily PPI is
with typical GERD symptoms not indicated.
1 day per week? Option C: Incorrect. The patient has symptoms only once a
Pantoprazole 20 mg BID week, and this is the initial treatment, so an ondemand PPI
Omeprazole 20 mg daily is not indicated.
Lansoprazole 15 mg daily as Option D: Correct. The patient has symptoms once per week
needed for GERD symptoms and is receiving initial treatment, so an ondemand H2RA is
(on-demand) Famotidine 20 indicated.
mg daily as needed for GERD
symptoms (on-demand)
4. Which one of the following Answer: A
medications may worsen Option A: Correct. Dihydropyridine calcium channel blockers lower
GERD symptoms by LES pressure.
decreasing lower esophageal Option B: Incorrect. Bisphosphonates are direct irritants to
sphincter pressure? esophageal mucosa.
Nifedipine Option C: Incorrect. NSAIDs are direct irritants to esophageal
Alendronate mucosa.
Naproxen Option D: Incorrect. Doxycycline is a direct irritant to esophageal
Doxycycline mucosa.
5. Which of the following
Answer: C
would be the LEAST
Option A: Incorrect. Calcium containing antacids are
appropriate medication for
appropriate initial treatment in mild-to-moderate GERD in
treating GERD in
pregnancy.
pregnancy?
Option B: Incorrect. It is appropriate to use a PPI to treat
Calcium carbonate tablets
GERD in pregnant women with frequent, severe heartburn.
Esomeprazole capsules
Option C: Correct. Magnesium trisilicate-containing antacids
Aluminum
should be avoided in pregnancy.
hydroxide/agnesium
Option D: Incorrect. It is appropriate to use a PPI to treat GERD
trisilicate tablets
in pregnant women with frequent, severe heartburn.
Lansoprazole capsules
,6. PPIs decrease stomach 6. Answer: A
acid by which of the Option A: Correct. This is the mechanism of action of the PPIs.
following mechanisms? Option B: Incorrect. This is the mechanism of action of the
Inhibiting gastric H2RAs.
H+/K+adenosine Option C: Incorrect. This is the mechanism of action of sucralfate.
triphosphatase in gastric Option D: Incorrect. This is the mechanism of action of
parietal cells Inhibiting metoclopramide.
histamine-2 receptors in
gastric parietal cells
Forming a viscous solution
that floats on the surface of
the gastric contents
Increasing GI motility
7. Answer: D
Option A: Incorrect. Prophylactic magnesium supplementation is not
7. Which of the following
indicated.
would be recommended
Option B: Incorrect. Prophylactic sodium bicarbonate
for preventing
supplementation is not indicated.
complications due to PPI
Option C: Incorrect. PPI dementia is not well
use? Magnesium
documented. Memantine would not be appropriate for
supplementation for
this indication.
potential
Option D: Correct. PPI-associated hypocalcemia would not
hypomagnesemia Sodium
require prophylactic calcium supplementation, but it is
bicarbonate reasonable to initiate calcium supplements for documented
supplementation for hypocalcaemia.
potential acute kidney
injury
Memantine prophylaxis
for PPI-associated
dementia
Calcium citrate
supplementation for
documented hypocalcemia
, 8. Which of the following 8. Answer: C
drug classes provides the Option A: Incorrect. Antacids can be useful adjunctive therapy but
most effective relief from are inferior to PPIs.
GERD symptoms? Option B: Incorrect. H2RAs are better than antacids but are
Antacids inferior to PPIs.
H2RAs Option C: Correct. PPIs are the most effective drug class for
PPIs relieving GERD symptoms.
Prokinetics Option D: Incorrect. Prokinetic agents are not routinely
recommended for treating GERD.
9. Answer: C
9. In which of the following Option A: Incorrect. This patient is having typical symptoms.
scenarios would endoscopy Option B: Incorrect. This patient appears to be a
be indicated? A 24-year-old "happy spitter."
pregnant woman with daily Option C: Correct. Weight loss is an alarm symptom. Option D:
heartburn symptoms A 2- Incorrect. This patient has typical symptoms of GERD and only
week-old infant who a history of asthma; he does not report wheezing.
regurgitates with every third
feeding
A 67-year-old man with
recent unexplained weight
loss
A 13-year-old boy with a
history of asthma and
heartburn 2 days per week
diabetes, mens/womens health, MDD, GAD, Insomnia)
Actual Test Questions with Detailed Verified Answers &
Rationales / Already Graded A
Terms in this set (210)
1. Which one of the Answer: C
following GERD symptom is
considered atypical and Option C: Correct. Wheezing is an atypical symptom and
requires further diagnostic may be a contributing factor in certain patients with
asthma.
evaluation? A. Heartburn
B. Regurgitation
C. Wheezing
D. None of the
abovesymptoms is
considered atypical
Answer: A
2. Which of the following Option A: Correct. Dexlansoprazole can be taken without
represents the correct order regard to meals.
of gastric acid suppression Option B: Incorrect. Lansoprazole should be taken 30 to 60
from most suppression to minutes prior to a meal.
least suppression? Option C: Incorrect. Omeprazole should be taken 30 to 60
a PPI > H2RA > Antacid b minutes prior to a meal.
PPI > Antacid > H2RA c Option D: Incorrect. Pantoprazole should be taken 30 to 60
Antacid > H2RA > PPI d minutes prior to a meal.
H2RA > PPI > Antacid
,3. What would be the best Answer: D
initial pharmacologic option Option A: Incorrect. The patient has symptoms only once a
in addition to lifestyle week, so a twice-daily PPI is not indicated. Option B: Incorrect.
modification for a patient The patient has symptoms only once a week, so a daily PPI is
with typical GERD symptoms not indicated.
1 day per week? Option C: Incorrect. The patient has symptoms only once a
Pantoprazole 20 mg BID week, and this is the initial treatment, so an ondemand PPI
Omeprazole 20 mg daily is not indicated.
Lansoprazole 15 mg daily as Option D: Correct. The patient has symptoms once per week
needed for GERD symptoms and is receiving initial treatment, so an ondemand H2RA is
(on-demand) Famotidine 20 indicated.
mg daily as needed for GERD
symptoms (on-demand)
4. Which one of the following Answer: A
medications may worsen Option A: Correct. Dihydropyridine calcium channel blockers lower
GERD symptoms by LES pressure.
decreasing lower esophageal Option B: Incorrect. Bisphosphonates are direct irritants to
sphincter pressure? esophageal mucosa.
Nifedipine Option C: Incorrect. NSAIDs are direct irritants to esophageal
Alendronate mucosa.
Naproxen Option D: Incorrect. Doxycycline is a direct irritant to esophageal
Doxycycline mucosa.
5. Which of the following
Answer: C
would be the LEAST
Option A: Incorrect. Calcium containing antacids are
appropriate medication for
appropriate initial treatment in mild-to-moderate GERD in
treating GERD in
pregnancy.
pregnancy?
Option B: Incorrect. It is appropriate to use a PPI to treat
Calcium carbonate tablets
GERD in pregnant women with frequent, severe heartburn.
Esomeprazole capsules
Option C: Correct. Magnesium trisilicate-containing antacids
Aluminum
should be avoided in pregnancy.
hydroxide/agnesium
Option D: Incorrect. It is appropriate to use a PPI to treat GERD
trisilicate tablets
in pregnant women with frequent, severe heartburn.
Lansoprazole capsules
,6. PPIs decrease stomach 6. Answer: A
acid by which of the Option A: Correct. This is the mechanism of action of the PPIs.
following mechanisms? Option B: Incorrect. This is the mechanism of action of the
Inhibiting gastric H2RAs.
H+/K+adenosine Option C: Incorrect. This is the mechanism of action of sucralfate.
triphosphatase in gastric Option D: Incorrect. This is the mechanism of action of
parietal cells Inhibiting metoclopramide.
histamine-2 receptors in
gastric parietal cells
Forming a viscous solution
that floats on the surface of
the gastric contents
Increasing GI motility
7. Answer: D
Option A: Incorrect. Prophylactic magnesium supplementation is not
7. Which of the following
indicated.
would be recommended
Option B: Incorrect. Prophylactic sodium bicarbonate
for preventing
supplementation is not indicated.
complications due to PPI
Option C: Incorrect. PPI dementia is not well
use? Magnesium
documented. Memantine would not be appropriate for
supplementation for
this indication.
potential
Option D: Correct. PPI-associated hypocalcemia would not
hypomagnesemia Sodium
require prophylactic calcium supplementation, but it is
bicarbonate reasonable to initiate calcium supplements for documented
supplementation for hypocalcaemia.
potential acute kidney
injury
Memantine prophylaxis
for PPI-associated
dementia
Calcium citrate
supplementation for
documented hypocalcemia
, 8. Which of the following 8. Answer: C
drug classes provides the Option A: Incorrect. Antacids can be useful adjunctive therapy but
most effective relief from are inferior to PPIs.
GERD symptoms? Option B: Incorrect. H2RAs are better than antacids but are
Antacids inferior to PPIs.
H2RAs Option C: Correct. PPIs are the most effective drug class for
PPIs relieving GERD symptoms.
Prokinetics Option D: Incorrect. Prokinetic agents are not routinely
recommended for treating GERD.
9. Answer: C
9. In which of the following Option A: Incorrect. This patient is having typical symptoms.
scenarios would endoscopy Option B: Incorrect. This patient appears to be a
be indicated? A 24-year-old "happy spitter."
pregnant woman with daily Option C: Correct. Weight loss is an alarm symptom. Option D:
heartburn symptoms A 2- Incorrect. This patient has typical symptoms of GERD and only
week-old infant who a history of asthma; he does not report wheezing.
regurgitates with every third
feeding
A 67-year-old man with
recent unexplained weight
loss
A 13-year-old boy with a
history of asthma and
heartburn 2 days per week
