NSG 223 | NSG223 Final Exam | Medical-
Surgical Nursing II Final Exam | Questions
and Correct Answers | Rated A+ | Latest
2025/2026 | Herzing
What is NADIR?
- Correct Answer - lowest point to which blood counts drop around 7
days post-chemo; most dangerous time for cancer pt.
What is the pharmacologic class for cyclophosphamide?
- Correct Answer - alkylating agent; nitrogen mustard
What is the action of cyclophosphamide?
- Correct Answer - acts by attaching to DNA and disrupting replication
What are some adverse effects for cyclophosphamide?
- Correct Answer - immunosuppression, bone marrow suppression,
n/v/d (tends to be severe), permanent sterility, haemorrhagic cystitis
What are some nursing considerations for cyclophosphamide?
,- Correct Answer - monitor platelet count prior to IM admin.; monitor
kidney function; increase urinary output to filter drug out; take with
meals; may need G-tube due to n/v/d
What is the pharmacologic class for cisplatin?
- Correct Answer - alkylating agent; platinum compound
What are some adverse effects of cisplatin?
- Correct Answer - ototoxicity, nephrotoxicity, pulmonary fibrosis,
hepatotoxicity, bone marrow suppression
What is the pharmacologic class for mercaptopurine?
- Correct Answer - antimetabolite; purine analog
What is the action mercaptopurine?
- Correct Answer - interrupts the DNA and RNA synthesis of protein
nucleotides
What is mercaptopurine used for?
- Correct Answer - variety of leukemias, non-Hodgkins lymphoma
What are some adverse effects of mercaptopurine?
,- Correct Answer - liver toxicity, mucositis, gastric ulcers, perforation,
reproductive toxicity, bone marrow suppression, GI discomfort, alopecia
What does mercaptopurine negatively interact with?
- Correct Answer - live virus vaccines
What are some nursing considerations for mercarptopurine?
- Correct Answer - monitor lfts, monitor kidney function, monitor for s/s of
GI bleed (coffee ground emesis, black tarry stools), do NOT get
pregnant for 6 months after completion of therapy
What is the lymphatic system?
- Correct Answer - protects the body from pathogens; effective immune
surveillance
What does the lymphatic system consist of?
- Correct Answer - lymphoid cells, tissues, spleen, thymus, tonsils, and
lymph nodes
What immunity is the lymphatic system apart of?
- Correct Answer - innate immunity
What is innate immunity?
, - Correct Answer - non-specific immunity; born with it; unable to
distinguish types of threats; involves skin and mucous membranes
What are cells of innate immunity?
- Correct Answer - neutrophils, macrophages, NK cells, T cells, B cells
What is the complement system?
- Correct Answer - consists of a group of proteins that are present in the
circulation that enables the body to localize and destroy infectious
pathogens
Functions of the complement system include:
- Correct Answer - enhance inflammatory response, increase
phagocytosis, destroy and clear pathogen from the body
What are mediators of innate immunity?
- Correct Answer - cytokines; interleukins, interferons, and tumor
necrosis factor (TNF)
What are the functions of cytokines?
- Correct Answer - produce chemotaxis of leukocytes; inhibiting viral
replication
Surgical Nursing II Final Exam | Questions
and Correct Answers | Rated A+ | Latest
2025/2026 | Herzing
What is NADIR?
- Correct Answer - lowest point to which blood counts drop around 7
days post-chemo; most dangerous time for cancer pt.
What is the pharmacologic class for cyclophosphamide?
- Correct Answer - alkylating agent; nitrogen mustard
What is the action of cyclophosphamide?
- Correct Answer - acts by attaching to DNA and disrupting replication
What are some adverse effects for cyclophosphamide?
- Correct Answer - immunosuppression, bone marrow suppression,
n/v/d (tends to be severe), permanent sterility, haemorrhagic cystitis
What are some nursing considerations for cyclophosphamide?
,- Correct Answer - monitor platelet count prior to IM admin.; monitor
kidney function; increase urinary output to filter drug out; take with
meals; may need G-tube due to n/v/d
What is the pharmacologic class for cisplatin?
- Correct Answer - alkylating agent; platinum compound
What are some adverse effects of cisplatin?
- Correct Answer - ototoxicity, nephrotoxicity, pulmonary fibrosis,
hepatotoxicity, bone marrow suppression
What is the pharmacologic class for mercaptopurine?
- Correct Answer - antimetabolite; purine analog
What is the action mercaptopurine?
- Correct Answer - interrupts the DNA and RNA synthesis of protein
nucleotides
What is mercaptopurine used for?
- Correct Answer - variety of leukemias, non-Hodgkins lymphoma
What are some adverse effects of mercaptopurine?
,- Correct Answer - liver toxicity, mucositis, gastric ulcers, perforation,
reproductive toxicity, bone marrow suppression, GI discomfort, alopecia
What does mercaptopurine negatively interact with?
- Correct Answer - live virus vaccines
What are some nursing considerations for mercarptopurine?
- Correct Answer - monitor lfts, monitor kidney function, monitor for s/s of
GI bleed (coffee ground emesis, black tarry stools), do NOT get
pregnant for 6 months after completion of therapy
What is the lymphatic system?
- Correct Answer - protects the body from pathogens; effective immune
surveillance
What does the lymphatic system consist of?
- Correct Answer - lymphoid cells, tissues, spleen, thymus, tonsils, and
lymph nodes
What immunity is the lymphatic system apart of?
- Correct Answer - innate immunity
What is innate immunity?
, - Correct Answer - non-specific immunity; born with it; unable to
distinguish types of threats; involves skin and mucous membranes
What are cells of innate immunity?
- Correct Answer - neutrophils, macrophages, NK cells, T cells, B cells
What is the complement system?
- Correct Answer - consists of a group of proteins that are present in the
circulation that enables the body to localize and destroy infectious
pathogens
Functions of the complement system include:
- Correct Answer - enhance inflammatory response, increase
phagocytosis, destroy and clear pathogen from the body
What are mediators of innate immunity?
- Correct Answer - cytokines; interleukins, interferons, and tumor
necrosis factor (TNF)
What are the functions of cytokines?
- Correct Answer - produce chemotaxis of leukocytes; inhibiting viral
replication
