Pagef1foff822
TEST BANK f
Katzung's Basic and Clinical Pharma
f f f f
cology, 16th Edition f f f
by Todd W. Vanderah, Chapters 1 - 66
f f f f f f f f
Katzung'sfBasicfandfClinicalfPharmacology
, Pagef2foff822
Table of Contents
f f
1.fIntroduction:fThefNaturefoffDrugsf&fDrugfDevelopmentf&fRegulation
2.fDrugfReceptorsf&fPharmacodynamics
3.fPharmacokineticsf&fPharmacodynamics:fRationalfDosingf&fthefTimefCoursefoffDrugfAction
4.fDrugfBiotransformation
5.fPharmacogenomics
6.fIntroductionftofAutonomicfPharmacology
7.fCholinoceptor-Activatingf&fCholinesterase-InhibitingfDrugs
8.fCholinoceptor-BlockingfDrugs
9.fAdrenoceptorfAgonistsf&fSympathomimeticfDrugs
10.fAdrenoceptorfAntagonistfDrugs
11.fAntihypertensivefAgents
12.fVasodilatorsf&fthefTreatmentfoffAnginafPectoris
13.fDrugsfUsedfinfHeartfFailure
14.fAgentsfUsedfinfCardiacfArrhythmias
15.fDiureticfAgents
16.fHistamine,fSerotonin,f&fthefErgotfAlkaloids
17.fVasoactivefPeptides
18.fThefEicosanoids:fProstaglandins,fThromboxanes,fLeukotrienes,f&fRelatedfCompounds
19.fNitricfOxide
20.fDrugsfUsedfinfAsthma
21.fIntroductionftofthefPharmacologyfoffCNSfDrugs
22.fSedative-HypnoticfDrugs
23.fThefAlcohols
24.fAntiseizurefDrugs
25.fGeneralfAnesthetics
26.fLocalfAnesthetics
27.fSkeletalfMusclefRelaxants
28.fPharmacologicfManagementfoffParkinsonismf&fOtherfMovementfDisorders
29.fAntipsychoticfAgentsf&fLithium
30.fAntidepressantfAgents
31.fOpioidfAgonistsf&fAntagonists
32.fDrugsfoffAbuse
33.fAgentsfUsedfinfCytopenias;fHematopoieticfGrowthfFactors
34.fDrugsfUsedfinfDisordersfoffCoagulation
35.fAgentsfUsedfinfDyslipidemia
36.fNonsteroidalfAnti-InflammatoryfDrugs,fDisease-
ModifyingfAntirheumaticfDrugs,fNonopioidfAnalgesics,f&fDrugsfUsedfinfGout
37.fHypothalamicf&fPituitaryfHormones
Katzung'sfBasicfandfClinicalfPharmacology
, Pagef3foff822
38.fThyroidf&fAntithyroidfDrugs
39.fAdrenocorticosteroidsf&fAdrenocorticalfAntagonists
40.fThefGonadalfHormonesf&fInhibitors
41.fPancreaticfHormonesf&fAntidiabeticfDrugs
42.fAgentsfThatfAffectfBonefMineralfHomeostasis
43.fBeta-Lactamf&fOtherfCellfWall-f&fMembrane-ActivefAntibiotics
44.fTetracyclines,fMacrolides,fClindamycin,fChloramphenicol,fStreptogramins,f&fOxazolidinones
45.fAminoglycosidesf&fSpectinomycin
46.fSulfonamides,fTrimethoprim,f&fQuinolones
47.fAntimycobacterialfDrugs
48.fAntifungalfAgents
49.fAntiviralfAgents
50.fMiscellaneousfAntimicrobialfAgents;fDisinfectants,fAntiseptics,f&fSterilants
51.fClinicalfUsefoffAntimicrobialfAgents
52.fAntiprotozoalfDrugs
53.fClinicalfPharmacologyfoffthefAntihelminthicfDrugs
54.fCancerfChemotherapy
55.fImmunopharmacology
56.fIntroductionftofToxicology:fOccupationalf&fEnvironmental
57.fHeavyfMetalfIntoxicationf&fChelators
58.fManagementfoffthefPoisonedfPatient
59.fSpecialfAspectsfoffPerinatalf&fPediatricfPharmacology
60.fSpecialfAspectsfoffGeriatricfPharmacology
61.fDermatologicfPharmacology
62.fDrugsfUsedfinfthefTreatmentfoffGastrointestinalfDiseases
63.fTherapeuticf&fToxicfPotentialfoffOver-the-CounterfAgents
64.fDietaryfSupplementsf&fHerbalfMedications
65.fRationalfPrescribingf&fPrescriptionfWriting
66.fImportantfDrugfInteractionsf&fTheirfMechanismsf
Katzung'sfBasicfandfClinicalfPharmacology
, Pagef4foff822
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
f f f f f f f f f f f
1.
Afnursefworkingfinfradiologyfadministersfiodineftofafpatientfwhofisfhavingfafc
omputedftomographyf(CT)fscan.fThefnursefworkingfonfthefoncologyfunitfadmin
istersfchemotherapyftofpatientsfwhofhavefcancer.fAtfthefPublicfHealthfDepartme
nt,fafnursefadministersfafmeasles-mumps-rubellaf(MMR)fvaccineftofaf14-month-
oldfchildfasfafroutinefimmunization.fWhichfbranchfoffpharmacologyfbestfdescri
besfthefactionsfoffallfthreef nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ANSWER: B
Feedback:
Pharmacologyfisfthefstudyfoffthefbiologicfeffectsfoffchemicals.fNursesfarefinvol
vedfwithfclinicalfpharmacologyforfpharmacotherapeutics,fwhichfisfafbranchfoffp
harmacologyfthatfdealsfwithfthefusesfoffdrugsftoftreat,fprevent,fandfdiagnosefdis
ease.fThefradiologyfnursefisfadministeringfafdrugftofhelpfdiagnosefafdisease.fThe
foncologyfnurse fisfadministeringfafdrugftofhelpftreatfafdisease.fPharmacoeconom
icsfincludesfanyfcostsfinvolvedfinfdrugf therapy.
Pharmacodynamicsfinvolvesfhowfafdrugfaffectsfthefbodyfandfp
harmacokineticsfisfhowfthefbodyfactsfonfthefbody.
2.
Afphysicianfhasforderedfintramuscularf(IM)finjectionsfoffmorphine,fafnarcoti
c,feveryf4fhoursfasfneededfforfpainfinfafmotorfvehiclefaccidentfvictim.fThefnursef
isfawarefthisfdrugfhasfafhighfabusefpotential.fUnderfwhatfcategoryfwouldfmorph
inefbefclassified?
A) SchedulefI
B) SchedulefII
Katzung'sfBasicfandfClinicalfPharmacology
TEST BANK f
Katzung's Basic and Clinical Pharma
f f f f
cology, 16th Edition f f f
by Todd W. Vanderah, Chapters 1 - 66
f f f f f f f f
Katzung'sfBasicfandfClinicalfPharmacology
, Pagef2foff822
Table of Contents
f f
1.fIntroduction:fThefNaturefoffDrugsf&fDrugfDevelopmentf&fRegulation
2.fDrugfReceptorsf&fPharmacodynamics
3.fPharmacokineticsf&fPharmacodynamics:fRationalfDosingf&fthefTimefCoursefoffDrugfAction
4.fDrugfBiotransformation
5.fPharmacogenomics
6.fIntroductionftofAutonomicfPharmacology
7.fCholinoceptor-Activatingf&fCholinesterase-InhibitingfDrugs
8.fCholinoceptor-BlockingfDrugs
9.fAdrenoceptorfAgonistsf&fSympathomimeticfDrugs
10.fAdrenoceptorfAntagonistfDrugs
11.fAntihypertensivefAgents
12.fVasodilatorsf&fthefTreatmentfoffAnginafPectoris
13.fDrugsfUsedfinfHeartfFailure
14.fAgentsfUsedfinfCardiacfArrhythmias
15.fDiureticfAgents
16.fHistamine,fSerotonin,f&fthefErgotfAlkaloids
17.fVasoactivefPeptides
18.fThefEicosanoids:fProstaglandins,fThromboxanes,fLeukotrienes,f&fRelatedfCompounds
19.fNitricfOxide
20.fDrugsfUsedfinfAsthma
21.fIntroductionftofthefPharmacologyfoffCNSfDrugs
22.fSedative-HypnoticfDrugs
23.fThefAlcohols
24.fAntiseizurefDrugs
25.fGeneralfAnesthetics
26.fLocalfAnesthetics
27.fSkeletalfMusclefRelaxants
28.fPharmacologicfManagementfoffParkinsonismf&fOtherfMovementfDisorders
29.fAntipsychoticfAgentsf&fLithium
30.fAntidepressantfAgents
31.fOpioidfAgonistsf&fAntagonists
32.fDrugsfoffAbuse
33.fAgentsfUsedfinfCytopenias;fHematopoieticfGrowthfFactors
34.fDrugsfUsedfinfDisordersfoffCoagulation
35.fAgentsfUsedfinfDyslipidemia
36.fNonsteroidalfAnti-InflammatoryfDrugs,fDisease-
ModifyingfAntirheumaticfDrugs,fNonopioidfAnalgesics,f&fDrugsfUsedfinfGout
37.fHypothalamicf&fPituitaryfHormones
Katzung'sfBasicfandfClinicalfPharmacology
, Pagef3foff822
38.fThyroidf&fAntithyroidfDrugs
39.fAdrenocorticosteroidsf&fAdrenocorticalfAntagonists
40.fThefGonadalfHormonesf&fInhibitors
41.fPancreaticfHormonesf&fAntidiabeticfDrugs
42.fAgentsfThatfAffectfBonefMineralfHomeostasis
43.fBeta-Lactamf&fOtherfCellfWall-f&fMembrane-ActivefAntibiotics
44.fTetracyclines,fMacrolides,fClindamycin,fChloramphenicol,fStreptogramins,f&fOxazolidinones
45.fAminoglycosidesf&fSpectinomycin
46.fSulfonamides,fTrimethoprim,f&fQuinolones
47.fAntimycobacterialfDrugs
48.fAntifungalfAgents
49.fAntiviralfAgents
50.fMiscellaneousfAntimicrobialfAgents;fDisinfectants,fAntiseptics,f&fSterilants
51.fClinicalfUsefoffAntimicrobialfAgents
52.fAntiprotozoalfDrugs
53.fClinicalfPharmacologyfoffthefAntihelminthicfDrugs
54.fCancerfChemotherapy
55.fImmunopharmacology
56.fIntroductionftofToxicology:fOccupationalf&fEnvironmental
57.fHeavyfMetalfIntoxicationf&fChelators
58.fManagementfoffthefPoisonedfPatient
59.fSpecialfAspectsfoffPerinatalf&fPediatricfPharmacology
60.fSpecialfAspectsfoffGeriatricfPharmacology
61.fDermatologicfPharmacology
62.fDrugsfUsedfinfthefTreatmentfoffGastrointestinalfDiseases
63.fTherapeuticf&fToxicfPotentialfoffOver-the-CounterfAgents
64.fDietaryfSupplementsf&fHerbalfMedications
65.fRationalfPrescribingf&fPrescriptionfWriting
66.fImportantfDrugfInteractionsf&fTheirfMechanismsf
Katzung'sfBasicfandfClinicalfPharmacology
, Pagef4foff822
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
f f f f f f f f f f f
1.
Afnursefworkingfinfradiologyfadministersfiodineftofafpatientfwhofisfhavingfafc
omputedftomographyf(CT)fscan.fThefnursefworkingfonfthefoncologyfunitfadmin
istersfchemotherapyftofpatientsfwhofhavefcancer.fAtfthefPublicfHealthfDepartme
nt,fafnursefadministersfafmeasles-mumps-rubellaf(MMR)fvaccineftofaf14-month-
oldfchildfasfafroutinefimmunization.fWhichfbranchfoffpharmacologyfbestfdescri
besfthefactionsfoffallfthreef nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
ANSWER: B
Feedback:
Pharmacologyfisfthefstudyfoffthefbiologicfeffectsfoffchemicals.fNursesfarefinvol
vedfwithfclinicalfpharmacologyforfpharmacotherapeutics,fwhichfisfafbranchfoffp
harmacologyfthatfdealsfwithfthefusesfoffdrugsftoftreat,fprevent,fandfdiagnosefdis
ease.fThefradiologyfnursefisfadministeringfafdrugftofhelpfdiagnosefafdisease.fThe
foncologyfnurse fisfadministeringfafdrugftofhelpftreatfafdisease.fPharmacoeconom
icsfincludesfanyfcostsfinvolvedfinfdrugf therapy.
Pharmacodynamicsfinvolvesfhowfafdrugfaffectsfthefbodyfandfp
harmacokineticsfisfhowfthefbodyfactsfonfthefbody.
2.
Afphysicianfhasforderedfintramuscularf(IM)finjectionsfoffmorphine,fafnarcoti
c,feveryf4fhoursfasfneededfforfpainfinfafmotorfvehiclefaccidentfvictim.fThefnursef
isfawarefthisfdrugfhasfafhighfabusefpotential.fUnderfwhatfcategoryfwouldfmorph
inefbefclassified?
A) SchedulefI
B) SchedulefII
Katzung'sfBasicfandfClinicalfPharmacology