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NURS 5315 UTA Exam 2 2024/2025 Exam Questions and Answers | A+ Score Assured

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NURS 5315 UTA Exam 2 2024/2025 Exam Questions and Answers | A+ Score Assured HIV EIA (3rd generation immunoassay) -

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NURS 5315 UTA Exam 2 2024/2025 Exam
Questions and Answers | A+ Score
Assured



HIV EIA (3rd generation immunoassay) - 🧠 ANSWER ✔✔can use urine,

saliva, or serum (most accurate), need to wait until 12 weeks post exposure

to see antibodies, >99% accurate

4th generation immunoassay- "gold standard"

measures P24 antigen

can test 10 days post exposure


Mast cell - 🧠 ANSWER ✔✔Cellular bags of granules located in loose

connective tisssue close to blood vessels. Activation initiates inflammatory

process.


Histamine - 🧠 ANSWER ✔✔Causes vasodilation, increases vascular

permeability, increases blood flow to the site of injury- causes erythema

and swelling.




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,Cytokines - 🧠 ANSWER ✔✔Soluble factors that contribute to the regulation

of innate or adaptive resistance by affecting other neighboring cells. Can be

pro-inflammatory or anti-inflammatory. Can react quickly or be more

delayed.


Leukotrines - 🧠 ANSWER ✔✔Released when mast cells degranulate,

prolong the inflammatory process. Cause vasodilation, attract neutrophils,

monocytes, and eosinophils.target of inhibition for singular.


Prostaglandins - 🧠 ANSWER ✔✔Released when mast cells degranulate,

are produced by the arachidonic pathway. Cause vasodilation, platelet

aggregation at site of injury, pain, and fever.


Chemotactic factors - 🧠 ANSWER ✔✔Biochemical substance that attracts

leukocyte to the site of inflammation


Neutrophils - 🧠 ANSWER ✔✔Predominant leukocyte at work during the

early stages of acute inflammation


Monocytes - 🧠 ANSWER ✔✔Become macrophages when entering the

tissue, responsible for presenting antigens to the CD4 cell which triggers T-

cell immunity and B-cell immunity.

Releases additional cytokines IL1, IL6, TNF.

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, Cytokine IL1 function - 🧠 ANSWER ✔✔Causes fever, activates phagocytes

& lymphocytes and also increases the release of IL6a


Cytokine IL6 function - 🧠 ANSWER ✔✔Stimulates production of acute

phase reactants and promotes growth and stimulation of RBCs


Cytokine TNF function - 🧠 ANSWER ✔✔Causes fever, increases synthesis

of proinflammatory proteins by liver, causes muscle wasting, induces

thrombosis


Cytokine growth factor function - 🧠 ANSWER ✔✔Promotes production and

maturation of neutrophils


Complement - 🧠 ANSWER ✔✔Functions include bacterial lysis,

vasodilation and increased vascular permeability, triggers mast cell

degranulation, chemotaxis, and opsonization.


Kinin - 🧠 ANSWER ✔✔Converted to bradykinin which is responsible for

pain and chemotaxis, and it increases vascular permeability and

vasodilation.


Coagulation cascade - 🧠 ANSWER ✔✔Factor XII activates kinin. Function

is to form fibrin mesh to stop bleeding and trap micro organisms.



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