TietzFundamentalsOf
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CLINICAL CHEMISTRY AND
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7thEditionByCarlA.Burtis
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TEST BANK , f
,TietzFundamentals of ClinicalChemistry and MolecularDiagnostics 7th Edition TestBank
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Table of contents: ,f ,f
I. Principles Of Laboratory Medicine
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Chapter1. Clinical Chemistry, Molecular Diagnostics, and LaboratoryMedicine
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Chapter2. Selectionand Analytical Evaluation of Methods —With Statistical Techniques
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Chapter3. Clinical Evaluation of Methods
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Chapter4. Evidence-Based LaboratoryMedicine
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Chapter5. Establishment and Useof Reference Values
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Chapter6. SpecimenCollection, Processing, and Other Preanalytical Variables
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Chapter7. QualityManagement ,f ,f ,f
II.Analytical Techniques And Instrumentation
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Chapter8. Principles of Basic Techniques and LaboratorySafety
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Chapter9. Optical Techniques ,f ,f ,f
Chapter10. Electrochemistryand Chemical Sensors
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Chapter11. Electrophoresis ,f ,f
Chapter12. Chromatography ,f ,f
Chapter13. Mass Spectrometry ,f ,f ,f
Chapter14. Enzyme and Rate Analyses ,f ,f ,f ,f ,f
Chapter15. Immunochemical Techniques ,f ,f ,f
Chapter16 Automation ,f ,f
Chapter17.Point-of-Care Instrumentation
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III. Analytes , f
Chapter18. Amino Acids, Peptides, and Proteins
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Chapter19. Serum Enzymes ,f ,f ,f
Chapter20. Tumor Markers and Cancer Genes
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Chapter21. KidneyFunction Tests — Creatinine, GFR, Urea, and UricAcid
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Chapter22. Carbohydrates ,f ,f
Chapter23. Lipids, Lipoproteins, Apolipoproteins,and OtherCardiacRisk Factors
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Chapter24. Electrolytes and Blood Gases
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Chapter25. Hormones ,f ,f
Chapter26. Catecholamines and Serotonin
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Chapter27. Vitamins, Trace Elements, Nutritional Assessment
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Chapter28.Hemoglobin, Iron, and Bilirubin
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Chapter29.Porphyrins and Porphyrias ,f ,f ,f ,f
Chapter30. Therapeutic Drugs and Their Management
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Chapter31. Clinical Toxicology ,f ,f ,f
Chapter32. Toxic Metals ,f , f ,f
IV. Pathophysiology
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Chapter33. Diabetes ,f ,f
,Chapter34. Cardiovascular Disease
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Chapter 35. KidneyDisease
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Chapter36. Physiologyand Disordersof Water, Electrolyte, and Acid-BaseMetabolism
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Chapter37. Liver Disease
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Chapter38. Gastrointestinal and PancreaticDiseases
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Chapter39. Disorders of Bone and Mineral Metabolism
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Chapter40. Disorders of the PituitaryGland
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Chapter41. Disorders of the Adrenal Cortex
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Chapter42. Thyroid Disorders
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Chapter43. Reproduction-Related Disorders
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Chapter44. Pregnancyand Prenatal Testing
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Chapter45. Newborn Screeningand Inborn Errors of Metabolism
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Chapter46. Pharmacogenetics
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V. Molecular Diagnostics
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Chapter47. Principles of Molecular Biology
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Chapter48. Nucleic Acid Techniques and Applications
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Chapter49. Genomes and NucleicAcid Alterations
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, TietzFundamentals ofClinical ChemistryandMolecularDiagnostics,7eBurtis Test Bank
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Chapter01:ClinicalChemistry,MolecularDiagnostics,andLaboratoryMedicineTest Bank
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MULTIPLECHOICE ,f
1. An individual working in a clinical chemistry laboratory is married to a sales representative who
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works for a company that sells chemistry laboratory supplies. When the laboratory manager
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requests alist of needed supplies, cost of supplies,and vendors,this individual only recommends the
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spouse’s company as the vendor. This is considered to be a(n):
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a. accountingissue. ,f
b. possibleconflict ofinterest. ,f ,f ,f
c. maintenanceofconfidentialityissue. ,f ,f ,f
d. problemwithresourceallocation. ,f ,f ,f
ANS: B , f
Concernhasbeenraisedovertheinterrelationshipsbetweenpractitionersinthemedicalfield and ,f ,f ,f ,f ,f ,f ,f ,f ,f ,f ,f ,f ,f
commercial suppliers of drugs, devices, equipment, etc., to the medical profession.
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Similarly, relationships have been scrutinized between clinical laboratorians and manufacturers ,f ,f ,f ,f ,f ,f ,f ,f ,f
and providers of diagnostic equipment and supplies. These concerns led the National Institutes of
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Health (NIH) in 1995 to require official institutional review of financial disclosurebyresearchers
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andmanagement ofsituations inwhichdisclosureindicatespotential conflicts of interest.
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DIF: 1 REF: , f Page 4-5 ,f OBJ: 6 |7 , f ,f ,f
2. A patient visits her physician stating that her prescribed painkiller is not working to reduce
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thepain followingher recent surgery. Afriendof the patient claims thatthesamepainkiller
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“worked wonders” to reduce her pain after the same surgery. The physician states that the
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difference in the effect of the drug might be caused by
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pharmacogenetics.
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a. epidemiology
b. aninheriteddisease ,f ,f
c. aconflictofinterest ,f ,f ,f
d. ageneticvariation in drug-metabolizingenzymes
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ANS: D , f
Pharmacogeneticsis thestudyofthegeneticvariation ofdrugmetabolism between individuals. ,f ,f ,f ,f ,f ,f ,f ,f ,f ,f ,f ,f
DIF: 1 REF: Page 3 , f , f ,f OBJ: 1 , f
3. John works in a molecular diagnostics laboratory and receives a blood sample that has the
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nameofaclosefriend printed onthebar-coded label. Thegenetictest that isordered onthe friend’s
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sample would provide diagnostic information about a disorder that has a poor prognosis, and the
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test is usuallyperformed byJohn. He asks a fellow employee to analyze the sample for him and not
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divulge the results. This ethical issue concerns:
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a. confidentialityofpatient geneticand medical information. ,f ,f ,f ,f ,f ,f
b. aconflict ofinterest. ,f ,f ,f
c. resourceallocation. ,f
d. diagnosticaccuracy. ,f