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HESI Pharmacology Exam 2025 - V3 (3 Set Exams) - Questions and Rationalized Answers - (NGN & Case studies) - 100% Verified $20.49
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  5. Pharmacology for NCLEX, ATI and HESI

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HESI Pharmacology Exam 2025 - V3 (3 Set Exams) - Questions and Rationalized Answers - (NGN & Case studies) - 100% Verified
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  • Pharmacology for NCLEX, ATI and HESI
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  • Pharmacology For NCLEX, ATI And HESI

**2025 HESI Pharmacology Exam V3 (3 Set Exams)** Prepare with confidence for your upcoming HESI exams using the comprehensive 2025 HESI Pharmacology Exam V3 (3 Set Exams). This expertly curated package includes three distinct full-length exams designed to mirror the latest HESI Pharmacology test...

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  • March 21, 2025
  • 103
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

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  • Pharmacology for NCLEX, ATI and HESI
  • Pharmacology for NCLEX, ATI and HESI

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HESI PHARMACOLOGY V3 EXAM
(3 Set Exams)
Actual Qs & Ans to Pass the Exam

HESI PHARMACOLOGY V3 EXAM 1………………………………… pg.02
HESI PHARMACOLOGY V3 EXAM 2………………………………… pg.33
HESI PHARMACOLOGY V3 EXAM 3…………………………………pg.68


This hesi test contains:
passing score Guarantee
Each Exam has 55 Ques and Ans
Format Set of Multiple-choice
questions with incorporating Next Generation NCLEX (NGN) and
Case studies questions
Expert-Verified Explanations & Solutions






, HESI PHARMACOLOGY V3 EXAM

──────────────────────────────────────────────────────
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1) CASE STUDY (NGN-Style Question)
──────────────────────────────────────────────────────
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A 54-year-old client with hypertension (HTN) and type 2 diabetes mellitus (T2DM) is
preparing to take the first dose of captopril. His daily medications include spironolactone
25 mg/day, metformin 500 mg twice a day, and insulin glargine 25 units daily. The
nurse outlines several instructions:

Instruction 1: Increase the insulin glargine dose by 3 units on the morning of the first
dose.
Instruction 2: Limit fluids for several days before the first dose.
Instruction 3: Lie down if blood pressure drops quickly after the first dose.
Instruction 4: Monitor blood pressure for several hours after the first dose.
Instruction 5: Hold spironolactone for 3 days prior to the first dose.

Question: For each nursing instruction below, indicate if it is Indicated (safe/appropriate)
or Contraindicated (unsafe/inappropriate) in preparing the client for the first dose of
captopril.

A. 1 and 2 are Indicated; 3, 4, 5 are Contraindicated
B. 1, 2, 5 are Contraindicated; 3, 4 are Indicated
C. 1, 4 are Indicated; 2, 3, 5 are Contraindicated
D. 3, 5 are Indicated; 1, 2, 4 are Contraindicated

Correct Answer: B (1, 2, 5 are Contraindicated; 3, 4 are Indicated)

──────────────────────────────────────────────────────
──
Expert-Verified Explanation:
• Instruction 1 (Increasing insulin glargine by 3 units that morning) is contraindicated.
Adjusting insulin solely for a new antihypertensive without a glycemic trend is


,inappropriate.
• Instruction 2 (Limiting fluids) is contraindicated; dehydration increases hypotensive
risk when starting an ACE inhibitor, which can precipitate acute renal problems.
• Instruction 3 (Lying down if blood pressure drops) is indicated. Captopril can cause
significant first-dose hypotension, so safety measures are appropriate.
• Instruction 4 (Monitoring blood pressure for several hours) is indicated to assess for
first-dose hypotension or orthostatic changes.
• Instruction 5 (Holding spironolactone for 3 days) is contraindicated; there is no routine
recommendation to stop potassium-sparing diuretics for 3 days prior to initiating
captopril unless there is a specific concern such as hyperkalemia.
Thus, #3 and #4 are correct instructions (Indicated), while #1, #2, and #5 are incorrect
(Contraindicated).

──────────────────────────────────────────────────────
──
2)
──────────────────────────────────────────────────────
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A client with major depression is receiving a new prescription for duloxetine. Which
information is MOST important for the nurse to obtain?

A. Family history of mental illness
B. Weight change in the last month
C. Liver function laboratory results
D. Recent use of other antidepressants

Correct Answer: C. Liver function laboratory results

──────────────────────────────────────────────────────
──
Expert-Verified Explanation:
Duloxetine (an SNRI) is potentially hepatotoxic, especially if underlying liver disease
exists (e.g., alcohol abuse, hepatitis). Monitoring hepatic enzymes (ALT, AST) is vital
before starting duloxetine and periodically afterward. While history of mental illness,
current weight, and prior antidepressant use are also important, the highest priority is to
evaluate the client’s liver function status to prevent serious adverse effects.



, ──────────────────────────────────────────────────────
──
3)
──────────────────────────────────────────────────────
──
Which nursing action has the HIGHEST priority when administering a dose of codeine
with acetaminophen to a client?

A. Advise the client that the medication should start working in about 30 minutes
B. Instruct the client to request assistance when ambulating to the bathroom
C. Tell the client to notify the nurse if the pain is not relieved
D. Administer a stool softener or laxative at the same time as the analgesic

Correct Answer: B. Instruct the client to request assistance when ambulating to the
bathroom

──────────────────────────────────────────────────────
──
Expert-Verified Explanation:
Codeine causes central nervous system depression, sedation, and potential orthostatic
hypotension. The highest immediate priority is to prevent injury from falls by ensuring
the client does not ambulate unassisted while medicated. Although all options may be
relevant, client safety is paramount, so instructing the client to request help is the top
priority.

──────────────────────────────────────────────────────
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4) CASE STUDY (NGN-Style, “Select All That Apply”)
──────────────────────────────────────────────────────
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A 54-year-old client with HTN and T2DM has the following lab values. The nurse wants
to ask questions related to possible fluid and electrolyte changes. Which questions
should the nurse ask? Select All That Apply:

• A. “Have you noticed the need to urinate less often?”
• B. “Are you taking any supplements?”
• C. “Do you use any salt substitutes?”

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