NU578 - Unit 1 Questions and Correct Detailed Answers (Verified Answers) ||Already Graded A+||Newest Version

NU578 - Unit 1 Questions and Correct Detailed
Answers (Verified Answers) ||Already Graded
A+||Newest Version
Quiz: Schedule I

Ans: Drugs in this schedule have no accepted medical use in the United States and have a
high abuse potential.




Examples are heroin, marijuana, LSD, peyote, etc.



Quiz: Schedule II

Ans: Drugs in this schedule have a high abuse potential with severe psychic or physical
dependence liability. Included are certain narcotic analgesics, stimulants, and depressant
drugs.



Examples are opium, morphine, codeine, hydromorphone, methadone, meperidine,
oxycodone, anileridine, cocaine, amphetamine, methamphetamine, phenmetrazine,
methylphenidate, amobarbital, pentobarbital, secobarbital, methaqualone, and
phencyclidine.



Quiz: Schedule III




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, Ans: Drugs in this schedule have an abuse potential less than those in Schedules I and II
and include compounds containing limited quantities of certain narcotic analgesic drugs,
and other drugs such as barbiturates, glutethimide, methyprylon, and chlorphentemine.



Any suppository dosage form containing amobarbital, secobarbital, or pentobarbital is in
this schedule.



Quiz: Schedule IV

Ans: Drugs in this schedule have an abuse potential less than those listed in Schedule III
and include such drugs as barbital, phenobarbital, chloral hydrate, ethchlorvynol,
meprobabmate, chlordizepoxide, diazepam, oxazepam, chloroazepate, flurazepam, etc.



Quiz: Schedule V

Ans: Drugs in this schedule have an abuse potential less than those listed in Schedule IV
and consist primarily of preparations containing limited quantities of certain narcotic
analgesic drugs used for antitussive and antidiarrheal purposes.



Quiz: Absorption

Ans: Process of drug movement from its site of administration into the blood



Quiz: Most common mechanism for drug absorption

Ans: passive diffusion



Quiz: First-pass effect

(presystemic metabolism)

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, Ans: Rapid hepatic inactivation of certain oral drugs




drug is metabolized (chemically altered) as it passes through either 1) gut wall, and 2) liver.



Quiz: Distribution

Ans: drug movement from the blood to the interstitial space of tissues and from there
into cells



Quiz: Barriers to distribution

Ans: - Blood brain barrier

- Placenta



Quiz: Physiologic Factors Affecting Distribution

Ans: - Perfusion

- Binding of drug to plasma protein

- Specialized Distribution Barriers



Quiz: Albumin

Ans: Binds acidic drugs



Quiz: Protein (albumin) binding




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, Ans: Prevents bound drug molecules from leaving the bloodstream




Prolongs the distribution phase (Increases half-life)



Quiz: alpha-1 acid glycoprotein

Ans: Binds basic drugs



Quiz: Reservoir effect

Ans:



Quiz: Blood-Brain Barrier (BBB)

Ans: no intercellular pores between brain capillary endothelial membranes due to the
presence of tight junctions between cells



Quiz: To gain access to the brain from the capillaries, drugs must

Ans: 1) diffuse across cells (lipid-soluble,

nonionized form)



or




2) or be actively transported by a carrier



Quiz: Placental Barrier


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