Test bank for Tietz Fundamentals of Clinical Chemistry
v v v v v v v
v and Molecular Diagnostics,
v v v
8th Edition by Nader Rifai, PhD
v v v v v
v Chapters 1 - 49v v v
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
v v v v v v v v v v v
Table of contents:
v v
I. Principles Of Laboratory Medicine
v v v v
Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
v v v v v v v v
Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
v v v v v v v v v v v
Chapter 3. Clinical Evaluation of Methods
v v v v v
Chapter 4. Evidence-Based Laboratory Medicine
v v v v
Chapter 5. Establishment and Use of Reference Values
v v v v v v v
Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
v v v v v v v v
Chapter 7. Quality Management
v v v
II. Analytical Techniques And Instrumentation
v v v v
Chapter 8. Principles of Basic Techniques and Laboratory Safety
v v v v v v v v
Chapter 9. Optical Techniques
v v v
Chapter 10. Electrochemistry and Chemical Sensors
v v v v v
Chapter 11. Electrophoresis
v v
Chapter 12. Chromatography
v v
Chapter 13. Mass Spectrometry
v v v
Chapter 14. Enzyme and Rate Analyses
v v v v v
Chapter 15. Immunochemical Techniques
v v v
Chapter 16 Automationv v
Chapter 17. Point-of-Care Instrumentation
v v v
III. Analytes
v
Chapter 18. Amino Acids, Peptides, and Proteins
v v v v v v
Chapter 19. Serum Enzymes
v v v
Chapter 20. Tumor Markers and Cancer Genes
v v v v v v
Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
v v v v v v v v v v v
Chapter 22. Carbohydrates
v v
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
v v v v v v v v v
Chapter 24. Electrolytes and Blood Gases
v v v v v
Chapter 25. Hormones v v
Chapter 26. Catecholamines and Serotonin
v v v v
Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
v v v v v v
Chapter 28. Hemoglobin, Iron, and Bilirubin
v v v v v
Chapter 29. Porphyrins and Porphyrias
v v v v
Chapter 30. Therapeutic Drugs and Their Management
v v v v v v
Chapter 31. Clinical Toxicology
v v v
Chapter 32. Toxic Metals
v v v
IV. Pathophysiology
v
Chapter 33. Diabetes v v
,Chapter 34. Cardiovascular Disease
v v v
Chapter 35. Kidney Disease
v v v
Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
v v v v v v v v v v
Chapter 37. Liver Disease
v v v
Chapter 38. Gastrointestinal and Pancreatic Diseases
v v v v v
Chapter 39. Disorders of Bone and Mineral Metabolism
v v v v v v v
Chapter 40. Disorders of the Pituitary Gland
v v v v v v
Chapter 41. Disorders of the Adrenal Cortex
v v v v v v
Chapter 42. Thyroid Disorders
v v v
Chapter 43. Reproduction-Related Disorders
v v v
Chapter 44. Pregnancy and Prenatal Testing
v v v v v
Chapter 45. Newborn Screening and Inborn Errors of Metabolism
v v v v v v v v
Chapter 46. Pharmacogenetics
v v
V. Molecular Diagnostics
v v
Chapter 47. Principles of Molecular Biology
v v v v v
Chapter 48. Nucleic Acid Techniques and Applications
v v v v v v
Chapter 49. Genomes and Nucleic Acid Alterations
v v v v v v
, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine Test
v v v v v v v v v
Bank
v
MULTIPLE CHOICE v
1. An individual working in a clinical chemistry laboratory is married to a sales representative
v v v v v v v v v v v v v
who works for a company that sells chemistry laboratory supplies. When the laboratory
v v v v v v v v v v v v v
manager requests a list of needed supplies, cost of supplies, and vendors, this individual
v v v v v v v v v v v v v v
onlyrecommends the spouse’s company as the vendor. This is considered to be a(n):
v v v v v v v v v v v v v
a. accounting issue. v
b. possible conflict of interest. v v v
c. maintenance of confidentiality issue. v v v
d. problem with resource allocation. v v v
ANS: B v
Concern has been raised over the interrelationships between practitioners in the medical
v v v v v v v v v v v
fieldand commercial suppliers of drugs, devices, equipment, etc., to the medical profession.
v v v v v v v v v v v v
Similarly, relationships have been scrutinized between clinical laboratorians and
v v v v v v v v v
manufacturers and providers of diagnostic equipment and supplies. These concerns led the
v v v v v v v v v v v v
National Institutes of Health (NIH) in 1995 to require official institutional review of financial
v v v v v v v v v v v v v v
disclosure by researchers and management of situations in which disclosure indicates
v v v v v v v v v v v
potentialconflicts of interest.
v v v
DIF: 1 REF: v Page 4-5 v OBJ: 6 | 7 v v v
2. A patient visits her physician stating that her prescribed painkiller is not working to
v v v v v v v v v v v v v
reduce the pain following her recent surgery. A friend of the patient claims that the same
v v v v v v v v v v v v v v v v
painkiller“worked wonders” to reduce her pain after the same surgery. The physician
v v v v v v v v v v v v
states that the difference in the effect of the drug might be caused by , which is studied
v v v v v v v v v v v v v v v v v
in pharmacogenetics.
v v
a. epidemiology
b. an inherited disease v v
c. a conflict of interest
v v v
d. a genetic variation in drug-metabolizing enzymes
v v v v v
ANS: D v
Pharmacogenetics is the study of the genetic variation of drug metabolism v v v v v v v v v v
betweenindividuals.
v
DIF: 1 REF: v Page 3 v OBJ: 1 v
3. John works in a molecular diagnostics laboratory and receives a
v v v v v v v v v v v v v v v v v v v
vblood sample that has the name of a close friend printed on the
v v v v v v v v v v v v
v bar-coded label. The genetic test that is ordered on the friend’s sample
v v v v v v v v v v v
v would provide diagnostic information about a disorder that has a poor
v v v v v v v v v v
v prognosis, and the v v
test is usually performed by John. He asks a fellow employee to
v v v v v v v v v v v
analyze the sample for him and not divulge the results. This ethical
v v v v v v v v v v v v
issue concerns:
v v
a. confidentiality of patient genetic and medical information. v v v v v v v v v
b. a conflict of interest.
v v v v
c. resource allocation. v
d. diagnostic accuracy. v
v v v v v v v
v and Molecular Diagnostics,
v v v
8th Edition by Nader Rifai, PhD
v v v v v
v Chapters 1 - 49v v v
,Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics 8th Edition Test Bank
v v v v v v v v v v v
Table of contents:
v v
I. Principles Of Laboratory Medicine
v v v v
Chapter 1. Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine
v v v v v v v v
Chapter 2. Selection and Analytical Evaluation of Methods — With Statistical Techniques
v v v v v v v v v v v
Chapter 3. Clinical Evaluation of Methods
v v v v v
Chapter 4. Evidence-Based Laboratory Medicine
v v v v
Chapter 5. Establishment and Use of Reference Values
v v v v v v v
Chapter 6. Specimen Collection, Processing, and Other Preanalytical Variables
v v v v v v v v
Chapter 7. Quality Management
v v v
II. Analytical Techniques And Instrumentation
v v v v
Chapter 8. Principles of Basic Techniques and Laboratory Safety
v v v v v v v v
Chapter 9. Optical Techniques
v v v
Chapter 10. Electrochemistry and Chemical Sensors
v v v v v
Chapter 11. Electrophoresis
v v
Chapter 12. Chromatography
v v
Chapter 13. Mass Spectrometry
v v v
Chapter 14. Enzyme and Rate Analyses
v v v v v
Chapter 15. Immunochemical Techniques
v v v
Chapter 16 Automationv v
Chapter 17. Point-of-Care Instrumentation
v v v
III. Analytes
v
Chapter 18. Amino Acids, Peptides, and Proteins
v v v v v v
Chapter 19. Serum Enzymes
v v v
Chapter 20. Tumor Markers and Cancer Genes
v v v v v v
Chapter 21. Kidney Function Tests — Creatinine, GFR, Urea, and Uric Acid
v v v v v v v v v v v
Chapter 22. Carbohydrates
v v
Chapter 23. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiac Risk Factors
v v v v v v v v v
Chapter 24. Electrolytes and Blood Gases
v v v v v
Chapter 25. Hormones v v
Chapter 26. Catecholamines and Serotonin
v v v v
Chapter 27. Vitamins, Trace Elements, Nutritional Assessment
v v v v v v
Chapter 28. Hemoglobin, Iron, and Bilirubin
v v v v v
Chapter 29. Porphyrins and Porphyrias
v v v v
Chapter 30. Therapeutic Drugs and Their Management
v v v v v v
Chapter 31. Clinical Toxicology
v v v
Chapter 32. Toxic Metals
v v v
IV. Pathophysiology
v
Chapter 33. Diabetes v v
,Chapter 34. Cardiovascular Disease
v v v
Chapter 35. Kidney Disease
v v v
Chapter 36. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism
v v v v v v v v v v
Chapter 37. Liver Disease
v v v
Chapter 38. Gastrointestinal and Pancreatic Diseases
v v v v v
Chapter 39. Disorders of Bone and Mineral Metabolism
v v v v v v v
Chapter 40. Disorders of the Pituitary Gland
v v v v v v
Chapter 41. Disorders of the Adrenal Cortex
v v v v v v
Chapter 42. Thyroid Disorders
v v v
Chapter 43. Reproduction-Related Disorders
v v v
Chapter 44. Pregnancy and Prenatal Testing
v v v v v
Chapter 45. Newborn Screening and Inborn Errors of Metabolism
v v v v v v v v
Chapter 46. Pharmacogenetics
v v
V. Molecular Diagnostics
v v
Chapter 47. Principles of Molecular Biology
v v v v v
Chapter 48. Nucleic Acid Techniques and Applications
v v v v v v
Chapter 49. Genomes and Nucleic Acid Alterations
v v v v v v
, Chapter 01: Clinical Chemistry, Molecular Diagnostics, and Laboratory Medicine Test
v v v v v v v v v
Bank
v
MULTIPLE CHOICE v
1. An individual working in a clinical chemistry laboratory is married to a sales representative
v v v v v v v v v v v v v
who works for a company that sells chemistry laboratory supplies. When the laboratory
v v v v v v v v v v v v v
manager requests a list of needed supplies, cost of supplies, and vendors, this individual
v v v v v v v v v v v v v v
onlyrecommends the spouse’s company as the vendor. This is considered to be a(n):
v v v v v v v v v v v v v
a. accounting issue. v
b. possible conflict of interest. v v v
c. maintenance of confidentiality issue. v v v
d. problem with resource allocation. v v v
ANS: B v
Concern has been raised over the interrelationships between practitioners in the medical
v v v v v v v v v v v
fieldand commercial suppliers of drugs, devices, equipment, etc., to the medical profession.
v v v v v v v v v v v v
Similarly, relationships have been scrutinized between clinical laboratorians and
v v v v v v v v v
manufacturers and providers of diagnostic equipment and supplies. These concerns led the
v v v v v v v v v v v v
National Institutes of Health (NIH) in 1995 to require official institutional review of financial
v v v v v v v v v v v v v v
disclosure by researchers and management of situations in which disclosure indicates
v v v v v v v v v v v
potentialconflicts of interest.
v v v
DIF: 1 REF: v Page 4-5 v OBJ: 6 | 7 v v v
2. A patient visits her physician stating that her prescribed painkiller is not working to
v v v v v v v v v v v v v
reduce the pain following her recent surgery. A friend of the patient claims that the same
v v v v v v v v v v v v v v v v
painkiller“worked wonders” to reduce her pain after the same surgery. The physician
v v v v v v v v v v v v
states that the difference in the effect of the drug might be caused by , which is studied
v v v v v v v v v v v v v v v v v
in pharmacogenetics.
v v
a. epidemiology
b. an inherited disease v v
c. a conflict of interest
v v v
d. a genetic variation in drug-metabolizing enzymes
v v v v v
ANS: D v
Pharmacogenetics is the study of the genetic variation of drug metabolism v v v v v v v v v v
betweenindividuals.
v
DIF: 1 REF: v Page 3 v OBJ: 1 v
3. John works in a molecular diagnostics laboratory and receives a
v v v v v v v v v v v v v v v v v v v
vblood sample that has the name of a close friend printed on the
v v v v v v v v v v v v
v bar-coded label. The genetic test that is ordered on the friend’s sample
v v v v v v v v v v v
v would provide diagnostic information about a disorder that has a poor
v v v v v v v v v v
v prognosis, and the v v
test is usually performed by John. He asks a fellow employee to
v v v v v v v v v v v
analyze the sample for him and not divulge the results. This ethical
v v v v v v v v v v v v
issue concerns:
v v
a. confidentiality of patient genetic and medical information. v v v v v v v v v
b. a conflict of interest.
v v v v
c. resource allocation. v
d. diagnostic accuracy. v
