AppliedgPathophysiologygAgConceptualgApproachgtogthegMechanismsgofgDiseaseg3rdgEditiongTestgBan
k
AppliedgPathophysiologygAgConceptualgApproachgtogthegMechani
smsgofgDiseaseg3rdgEditiongBraungTestgBank
Chapterg1IntroductiongtogPathophysiology
1. Thegnucleusg ,gwhichgisgessentialgforgfunctiongandgsurvivalgofgthegcell.
A) isgthegsitegofgproteingsynthesis
B) containsgtheggeneticgcode
C) transformsgcellulargenergy
D) initiatesgaerobicgmetabolism
2. Althoughgenergygisgnotgmadegingmitochondria,gtheygaregknowngasgthegpower
gplantsgofgthegcellgbecausegthey:
A) containgRNAgforgproteingsynthesis.
B) utilizegglycolysisgforgoxidativegenergy.
C) extractgenergygfromgorganicgcompounds.
D) storegcalciumgbondsgforgmusclegcontractions.
3. Althoughgthegbasicgstructuregofgthegcellgplasmagmembranegisgformedgbygaglipid
gbilayer,gmostgofgthegspecificgmembranegfunctionsgaregcarriedgoutgby:
A) boundgandgtransmembranegproteins.
B) complex,glonggcarbohydrategchains.
C) surfacegantigensgandghormonegreceptors.
D) aggatinggsystemgofgselectivegiongchannels.
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, AppliedgPathophysiologygAgConceptualgApproachgtogthegMechanismsgofgDiseaseg3rdgEditiongTestgBan
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4. Togeffectivelygrelaygsignals,gcell-to-
cellgcommunicationgutilizesgchemicalgmessengergsystemsgthat:
A) displacegsurfacegreceptorgproteins.
B) accumulategwithingcellggapgjunctions.
C) bindgtogcontractilegmicrofilaments.
D) releasegsecretionsgintogextracellulargfluid.
5. Aerobicgmetabolism,galsogknowngasgoxidativegmetabolism,gprovidesgenergygby:
A) removinggthegphosphategbondsgfromgATP.
B) combiningghydrogengandgoxygengtogformgwater.
C) activatinggpyruvategstoredgingthegcytoplasm.
D) breakinggdowngglucosegtogformglacticgacid.
6. Exocytosis,gthegreversegofgendocytosis,gisgimportantging
intogthe
extracellulargfluid.
g
A) Engulfinggandgingestinggfluidgandgproteinsgforgtransport
B) Killing,gdegrading,gandgdissolvinggharmfulgmicroorganisms
C) Removinggcellulargdebrisgandgreleasinggsynthesizedgsubstances
D) Destructiongofgparticlesgbyglysosomalgenzymesgforgsecretion
7. Thegprocessgresponsiblegforggeneratinggandgconductinggmembranegpotentialsgis:
A) diffusiongofgcurrent-carryinggions.
B) millivoltagegofgelectricalgpotential.
C) polarizationgofgchargedgparticles.
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, AppliedgPathophysiologygAgConceptualgApproachgtogthegMechanismsgofgDiseaseg3rdgEditiongTestgBan
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D) iongchannelgneurotransmission.
8. Epithelialgtissuesgaregclassifiedgaccordinggtogthegshapegofgthegcellsgandgthegn
umbergofglayers.gWhichgofgthegfollowinggisgagcorrectlygmatchedgdescriptiong
andgtypegofgepithelialgtissue?
A) Simplegepithelium:gcellsgingcontactgwithgintercellulargmatrix;gsomegdognot
gextendgtogsurface
B) Stratifiedgepithelium:gsingleglayergofgcells;gallgcellsgrestgongbasement
gmembrane
C) Glandulargepithelium:garisegfromgsurfacegepitheliagandgunderlying
gconnectivegtissue
D) Pseudostratifiedgepithelium:gmultipleglayersgofgcells;gdeepestglayergrestsgon
gbasementgmembrane
9. Connectivegtissuegcontainsgfibroblastsgthatgaregresponsiblegfor:
A) providinggagfibrousgframeworkgforgcapillaries.
B) synthesisgofgcollagen,gelastin,gandgreticulargfibers.
C) forminggtendonsgandgthegfasciagthatgcoversgmuscles.
D) fillinggspacesgbetweengtissuesgtogkeepgorgansgingplace.
10. Althoughgallgmusclegtissuegcellsghavegsomegsimilarities,gsmoothgmuscleg(also
gknowngasginvoluntarygmuscle)gdiffersgby:
A) havinggdensegbodiesgattachedgtogactingfilaments.
B) containinggsarcomeresgbetweengZglinesgandgMgbands.
C) havinggrapidgcontractionsgandgabundantgcross-striations.
D) contractinggingresponsegtogincreasedgintracellulargcalcium.
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, AppliedgPathophysiologygAgConceptualgApproachgtogthegMechanismsgofgDiseaseg3rdgEditiongTestgBan
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11. Whichgofgthegfollowinggaspectsgofgthegfunctiongofgthegnucleusgisgperformedgby
gribosomalgRNAg(rRNA)?
A) CopyinggandgcarryinggDNAginstructionsgforgproteingsynthesis
B) Carryinggaminogacidsgtogthegsitegofgproteingsynthesis
C) Providinggthegsitegwheregproteingsynthesisgoccurs
D) Regulatinggandgcontrollinggproteingsynthesis
12. Breakdowngandgremovalgofgforeigngsubstancesgandgworn-
outgcellgpartsgaregperformedgbygwhichgofgthegfollowinggorganelles?
A) Lysosomes
B) Golgigapparatus
C) Ribosomes
D) Endoplasmicgreticulumg(ER)
13. Impairmentgingthegfunctiongofgperoxisomesgwouldgresultgin:
A) inadequategsitesgforgproteingsynthesis.
B) anginabilitygtogtransportgcellulargproductsgacrossgthegcellgmembrane.
C) insufficientgenergygproductiongwithingagcell.
D) accumulationgofgfreegradicalsgingthegcytoplasm.
14. Aftergseveralgmonthsgofgtryinggtogconceive,gagcouplegisgundergoinggfertilitygtes
ting.gSemenganalysisgindicatesgthatgthegmansgspermghavegdecreasedgmotility,gag
findinggthatgisgthoughtgtogunderliegthegcouplesginabilitygtogbecomegpregnant.
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k
AppliedgPathophysiologygAgConceptualgApproachgtogthegMechani
smsgofgDiseaseg3rdgEditiongBraungTestgBank
Chapterg1IntroductiongtogPathophysiology
1. Thegnucleusg ,gwhichgisgessentialgforgfunctiongandgsurvivalgofgthegcell.
A) isgthegsitegofgproteingsynthesis
B) containsgtheggeneticgcode
C) transformsgcellulargenergy
D) initiatesgaerobicgmetabolism
2. Althoughgenergygisgnotgmadegingmitochondria,gtheygaregknowngasgthegpower
gplantsgofgthegcellgbecausegthey:
A) containgRNAgforgproteingsynthesis.
B) utilizegglycolysisgforgoxidativegenergy.
C) extractgenergygfromgorganicgcompounds.
D) storegcalciumgbondsgforgmusclegcontractions.
3. Althoughgthegbasicgstructuregofgthegcellgplasmagmembranegisgformedgbygaglipid
gbilayer,gmostgofgthegspecificgmembranegfunctionsgaregcarriedgoutgby:
A) boundgandgtransmembranegproteins.
B) complex,glonggcarbohydrategchains.
C) surfacegantigensgandghormonegreceptors.
D) aggatinggsystemgofgselectivegiongchannels.
TestgBank Pageg1
, AppliedgPathophysiologygAgConceptualgApproachgtogthegMechanismsgofgDiseaseg3rdgEditiongTestgBan
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4. Togeffectivelygrelaygsignals,gcell-to-
cellgcommunicationgutilizesgchemicalgmessengergsystemsgthat:
A) displacegsurfacegreceptorgproteins.
B) accumulategwithingcellggapgjunctions.
C) bindgtogcontractilegmicrofilaments.
D) releasegsecretionsgintogextracellulargfluid.
5. Aerobicgmetabolism,galsogknowngasgoxidativegmetabolism,gprovidesgenergygby:
A) removinggthegphosphategbondsgfromgATP.
B) combiningghydrogengandgoxygengtogformgwater.
C) activatinggpyruvategstoredgingthegcytoplasm.
D) breakinggdowngglucosegtogformglacticgacid.
6. Exocytosis,gthegreversegofgendocytosis,gisgimportantging
intogthe
extracellulargfluid.
g
A) Engulfinggandgingestinggfluidgandgproteinsgforgtransport
B) Killing,gdegrading,gandgdissolvinggharmfulgmicroorganisms
C) Removinggcellulargdebrisgandgreleasinggsynthesizedgsubstances
D) Destructiongofgparticlesgbyglysosomalgenzymesgforgsecretion
7. Thegprocessgresponsiblegforggeneratinggandgconductinggmembranegpotentialsgis:
A) diffusiongofgcurrent-carryinggions.
B) millivoltagegofgelectricalgpotential.
C) polarizationgofgchargedgparticles.
TestgBank Pageg2
, AppliedgPathophysiologygAgConceptualgApproachgtogthegMechanismsgofgDiseaseg3rdgEditiongTestgBan
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D) iongchannelgneurotransmission.
8. Epithelialgtissuesgaregclassifiedgaccordinggtogthegshapegofgthegcellsgandgthegn
umbergofglayers.gWhichgofgthegfollowinggisgagcorrectlygmatchedgdescriptiong
andgtypegofgepithelialgtissue?
A) Simplegepithelium:gcellsgingcontactgwithgintercellulargmatrix;gsomegdognot
gextendgtogsurface
B) Stratifiedgepithelium:gsingleglayergofgcells;gallgcellsgrestgongbasement
gmembrane
C) Glandulargepithelium:garisegfromgsurfacegepitheliagandgunderlying
gconnectivegtissue
D) Pseudostratifiedgepithelium:gmultipleglayersgofgcells;gdeepestglayergrestsgon
gbasementgmembrane
9. Connectivegtissuegcontainsgfibroblastsgthatgaregresponsiblegfor:
A) providinggagfibrousgframeworkgforgcapillaries.
B) synthesisgofgcollagen,gelastin,gandgreticulargfibers.
C) forminggtendonsgandgthegfasciagthatgcoversgmuscles.
D) fillinggspacesgbetweengtissuesgtogkeepgorgansgingplace.
10. Althoughgallgmusclegtissuegcellsghavegsomegsimilarities,gsmoothgmuscleg(also
gknowngasginvoluntarygmuscle)gdiffersgby:
A) havinggdensegbodiesgattachedgtogactingfilaments.
B) containinggsarcomeresgbetweengZglinesgandgMgbands.
C) havinggrapidgcontractionsgandgabundantgcross-striations.
D) contractinggingresponsegtogincreasedgintracellulargcalcium.
TestgBank Pageg3
, AppliedgPathophysiologygAgConceptualgApproachgtogthegMechanismsgofgDiseaseg3rdgEditiongTestgBan
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11. Whichgofgthegfollowinggaspectsgofgthegfunctiongofgthegnucleusgisgperformedgby
gribosomalgRNAg(rRNA)?
A) CopyinggandgcarryinggDNAginstructionsgforgproteingsynthesis
B) Carryinggaminogacidsgtogthegsitegofgproteingsynthesis
C) Providinggthegsitegwheregproteingsynthesisgoccurs
D) Regulatinggandgcontrollinggproteingsynthesis
12. Breakdowngandgremovalgofgforeigngsubstancesgandgworn-
outgcellgpartsgaregperformedgbygwhichgofgthegfollowinggorganelles?
A) Lysosomes
B) Golgigapparatus
C) Ribosomes
D) Endoplasmicgreticulumg(ER)
13. Impairmentgingthegfunctiongofgperoxisomesgwouldgresultgin:
A) inadequategsitesgforgproteingsynthesis.
B) anginabilitygtogtransportgcellulargproductsgacrossgthegcellgmembrane.
C) insufficientgenergygproductiongwithingagcell.
D) accumulationgofgfreegradicalsgingthegcytoplasm.
14. Aftergseveralgmonthsgofgtryinggtogconceive,gagcouplegisgundergoinggfertilitygtes
ting.gSemenganalysisgindicatesgthatgthegmansgspermghavegdecreasedgmotility,gag
findinggthatgisgthoughtgtogunderliegthegcouplesginabilitygtogbecomegpregnant.
TestgBank Pageg4