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sympathetic stimulation - ✔✔The process that results in preparing the
body for exercise; "fight or flight" mechanism;
- increased heart rate
- dilated pupils
constriction of kidneys and digestive tract
alpha receptors - ✔✔adrenergic receptors that are found in smooth muscles
and constrict arteries when stimulated by norepinephrine and epinephrine;
increases bp and blood flow to heart
A1 receptors - ✔✔involved in smooth muscle contraction;
- contraction of bronchioles, blood vessels, internal urethral sphincter, and
muscular wall
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,A2 receptors - ✔✔-Located on presynaptic axons
-When stimulated, result in inhibition of norepinephrine release in the
synapse; this may be a negative-feedback system
Beta receptors - ✔✔adrenergic receptors that are found in the heart, lungs,
and vascular smooth muscle; involved in the relaxation of cells and dilation
of blood vessels and found on tissues throughout the body
B1 receptors - ✔✔increase cardiac output by increasing heart rate, stroke
volume, and rate of relaxation through dilation
B2 receptors - ✔✔smooth muscle relaxation throughout the body; ex)
relaxation of muscular war and relaxation of internal urethral sphincter
muscarinic ACH receptors - ✔✔Can be stimulated by muscarine (from
poisonous mushrooms)
Found in CNS and plasma membrane of smooth and cardiac muscles and
glands innervated by autonomic motor neurons; triggers parasympathetic
stimulation
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, parasympathetic stimulation - ✔✔'rest and digest'; lowers ventilation rate,
release blood flow to gut and other organs, decrease heart rate and bp
water soluble hormone - ✔✔a lipophobic hormone that binds to a receptor
on or within the plasma membrane to initiate an intracellular signalling
cascade ex) glucagon, insulin, ADH, oxytocin
water soluble hormone steps - ✔✔1. bind to receptors on the surface of the
cell which are coupled to internally anchored G proteins
2. signal transduction: the receptor complex activates second messenged
(cAMP, Ca2+) which initiate cell activity
3. use of second messengers enables the amplification of the initial signal as
more molecules are activated (enzyme cascade)
4. enzyme 3 stimulates the breakdown of glycogen into glucose
lipid soluble hormone - ✔✔liphophilic hormone that can move freely into
membrane and into cell ex) progesterone, estrogen, testosterone
lipid soluble hormone steps - ✔✔1. hormone diffuses through the plasma
membrane of the target cell
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