National Board of Medical Examiners (NBME)
NBME USMLE (United States Medical Licensing
Examination): USMLE Step 1, 2 and 3
NBME CBSSA & NBME CBSE Comprehensive Basic
Science Self- Assessment and Examination
Course Title and Number: NBME CBSSA, NBME CBSE, and
NBME USMLE Exam
Exam Title: NBME
Exam Date: Exam 2025- 2026
Instructor: ____ [Insert Instructor’s Name] _______
Student Name: ___ [Insert Student’s Name] _____
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Examination
Time: - ____ Hours: ___ Minutes
Instructions:
1. Read each question carefully.
2. Answer all questions.
3. Use the provided answer sheet to mark your responses.
4. Ensure all answers are final before submitting the exam.
5. Please answer each question below and click Submit when you
have completed the Exam.
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Learning Resources.
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CBSSA Exam Review NBME Comprehensive Basic
Science Self- Assessment Exam Review Questions
and Answers | 100% Pass Guaranteed | Graded A+
|
2025- 2026
NBME CBSSA & NBME CBSE Comprehensive
Basic Science Self- Assessment and Examination
NBME USMLE (United States Medical Licensing
Examination): USMLE Step 1, 2 and 3
Read All Instructions Carefully and Answer All the
Questions Correctly Good Luck: -
1. 6yo boy from Russia with unstable gait and incoordination
for 2 weeks. Pale, bulky stools for 4 years and two
episodes of bacterial pneumonia and chronic cough since
age 1 year. 3%ile for height/weight. Neuro exam shows
ataxia, no DTRs, loss of proprioception. Stool shows inc fat
concentration. Vitamin deficient? - =Answer>> Vitamin
E
2. 54yo F 1 week after sudden loss of vision in left eye,
returned within 1 day. 3-month hx of progressive SOB with
exertion. Echocardiography shows mass in the left atrium
of the heart. Lesion is resected, photomicrograph of it is
shown. Which describes the lesion? - =Answer>>
Myxoma (most commonly appear in the LA)
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3. 27yo primigravid woman at 34 weeks' with nausea and
vomiting, and abdominal pain for 12 hours. Everything's
been normal. BP is now 164/102, and right upper quadrant
tenderness. Labs show Hb 7.4, HCT 24%, Platelets 72k, Cr
1.2, total bili 2.3, AST 112, ALT 126. Peripheral blood
smear will show? - =Answer>> Schistocytes
4. 60yo F 3 hours after sudden onset ankle pain. 4-year Hx of
increasing serum creatinine concentrations. Began
furosemide 1 month ago, also takes glipizide. P 120/min,
resp 25/min, BP 150/100. Joint fluid shows negatively
birefringent crystals. Increased risk of which complications
of underlying process causing joint findings? -
=Answer>> Nephrolithiasis
5. 56yo F follow-up 8 weeks after recovering from
pneumococcal pneumonia. Chest X-rays normal. Which
allowed this resolution to occur? - =Answer>>
Maintenance of the BM integrity
6. 29yo F with 5-week hx of fatigue and 4-day hx of heart
palpitations and anxiety. Has primary hypothyroidism Rx
with triiodothyronine, but she has doubled the dose
because of fatigue. TFT will show which? - =Answer>>
TSH: decreased
7. Free thyroxine: decreased (measure of T4--> decreases
when T3 increase)
8. Free triidothyronine: increased (T3)
9. 20yo F has multiple neurofibromas. Mom, uncle, and
brothers with similar lesions. Mode of inheritance? -
=Answer>> AD
10. 45yo M with yellow skin. Drinks eight to ten 12-ounce
cans of beers daily for 10 days. Liver is tender. Serum:
total bili 5.9, Alk Phos 210, AST 110, ALT 69, gamma-
glutamyltransferase 25 (n = 0-30). Liver biopsy will show?
- =Answer>> Mallory hyaline--> alcoholic hepatitis
11. 50yo M smoked 2 packs per day for 34 years, with
SOB on exertion, chronic cough, and wheezing. Increased
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AP diameter, diminished breath sounds, scattered rhonchi.
Which Lab abnormalities is expected? - =Answer>>
Chronic bronchitis--> increased PaCO2--> to compensate,
increase HCO3-
12. 35yo M uses crack cocaine daily, with 2-hour Hx of
substernal chest pain. T 37C, P 110/min, BP 160/100. Most
appropriate next step? - =Answer>> Admit the patient
for possible myocardial ischemia
13. 54yo F with hypertension and bilateral renal artery
stenosis starts taking NSAIDS for back pain. Her Cr
concentration increases from 1.0 to 5.0. Cause is due to
inhibiting which? - =Answer>> Vasodilation of the
afferent arteriole
14. 83yo M brought to ED after being found at home
bedridden and confused. No meds. P 100/min, BP 85/50.
BP unchanged after 1L IV saline. Pulmonary artery
catheter shows: Cardiac output high, PCWP low, systemic
vascular resistance low. Cause of hypotension? -
=Answer>> Early septic shock (only form with
decreased SVR)
15. 32yo M with 3-month hx of swelling and breast
tenderness. Receiving thyroid hormone and steroid
replacements since removal of pituitary adenoma 2 years
ago. Began hCG injections 4 months ago. Most likely
binding site of hCG causing gynecomastia? -
=Answer>> Acts on testes and leads to increased
estrogen
16. 38yo F with 3-day hx of sore throat. Photo shown of
throat. Which nerves is tested by saying "ah," elevating
uvula at tip of the arrow? - =Answer>> Vagus
17. 8yo boy with disruptive behavior, interrupts, always
moving, trouble completing tasks. Drug with which
mechanism is appropriate? - =Answer>> Increased
release of DA and NE
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