National Board of Medical Examiners (NBME)
NBME USMLE (United States Medical Licensing
Examination): USMLE Step 1, 2 and 3
NBME CBSSA & NBME CBSE Comprehensive Basic
Science Self- Assessment and Examination
Course Title and Number: NBME CBSSA, NBME CBSE, and
NBME USMLE Exam
Exam Title: NBME
Exam Date: Exam 2025- 2026
Instructor: ____ [Insert Instructor’s Name] _______
Student Name: ___ [Insert Student’s Name] _____
Student ID: ____ [Insert Student ID] _____________
Examination
Time: - ____ Hours: ___ Minutes
Instructions:
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2. Answer all questions.
3. Use the provided answer sheet to mark your responses.
4. Ensure all answers are final before submitting the exam.
5. Please answer each question below and click Submit when you
have completed the Exam.
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automatically when the time expires
7. This is Exam which will assess your knowledge on the course
Learning Resources.
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USMLE Step 2 CK (Clinical Knowledge) Exam Review NBME First
Aid for CK, Secrets for CK, and USMLE World Questions and
Answers | 100% Pass Guaranteed | Graded A+ |
2025- 2026
NBME USMLE (United States Medical Licensing Examination)
USMLE Step 1, Step 2 CK (Clinical Knowledge), Step 2 CS
(Clinical Skills - discontinued), & Step 3
NBME CBSSA & NBME CBSE Comprehensive Basic Science Self-
Assessment and Examination
National Board of Medical Examiners (NBME)
Read All Instructions Carefully and Answer All the
Questions Correctly Good Luck: -
steroids - =Answer>> inhibit IL-1 production
methotrexate - =Answer>> folic acid antagonist, inhibits
DHF reductase, S-phase specific, inhibits DNA synthesis
cyclosporine - =Answer>> calcineurin inhibitor; inhibits IL-2
production; nephrotoxic, gum hypertrophy, hursutism
tacrolimus (FK506) - =Answer>> calcineurin inhibitor;
inhibits signaling thru T cell receptor
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mycophenylate mofeil - =Answer>> prevents T cell
activation
azathioprine - =Answer>> antineoplastic; cleaved to
mercaptopurine; inhibits DNA/RNA synthesis; BM suppression
antithymocyte globulin (OKT3) - =Answer>> antibody
against CD3 on T cells; causes pulmonary edema
basiliximab, daclizumab - =Answer>> monoclonal antibody
to IL-2 receptor
fetal heart tones begin at - =Answer>> 10-12 weeks
fetal quickening (movement) occurs at - =Answer>> 17-18
weeks
4 measurements that can be taken from fetal US -
=Answer>> crown-rump length, biparietal diameter, femur
length, abdominal circumference
abdominal circumference - =Answer>> most reliable
parameter for set. fetal weight in cases of fetal growth
restriction
Gestational sac is visible by what gestational age? -
=Answer>> five weeks
b-hCG peaks when? - =Answer>> 10 weeks GA
average increase in weight during pregnancy - =Answer>>
25 lb (11 kg)
additional kcal needed during pregnancy - =Answer>> 100-
300 kcal/day
when should supplemental iron be started in a pregnant
woman? - =Answer>> first prenatal visit
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What 2 supplement to pregnant vegans need? - =Answer>>
Vit D, Vit B12
What cardiovascular parameters DECREASE during pregnancy?
- =Answer>> blood pressure and peripheral vascular
resistance
What happens to electrolytes during pregnancy? -
=Answer>> NOTHING! Remain unchanged.
What causes herpangina? - =Answer>> coxsackievirus (an
enterovirus)
How do you screen for Hep C on the first prenatal visit? What
about Hep B? - =Answer>> Hep C - history. Hep B - HBsAg
When is gestational diabetes screened for in pregnancy? -
=Answer>> weeks 24-28
How are AFP results reported? - =Answer>> multiples of the
median (MoM)
Quad screen shows "pan-low". - =Answer>> trisomy 18 (low
AFP, low estriol, low b-hCG, low inhibin A)
Quad screen shows low AFP, low estriol, high b-hCG, high
inhibin A. - =Answer>> Down syndrome
Risk of fetal loss during chorionic villus sampling -
=Answer>> 1%
Third trimester test used to detect presence of
phosphatidylglycerol - =Answer>> amniocentesis
tetratogen that can cause lack of cranial ossification -
=Answer>> ACEI
tetratogenic defects of streptomycin or kanamycin -
=Answer>> hearing loss; CN VIII damage
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